scholarly journals Optical Sectioning of Live Mammal with Near-Infrared Light Sheet

2018 ◽  
Author(s):  
Feifei Wang ◽  
Hao Wan ◽  
Jingying Yue ◽  
Mingxi Zhang ◽  
Zhuoran Ma ◽  
...  
Keyword(s):  
Near Infrared ◽  
Optical Excitation ◽  
Light Sheet ◽  
Infrared Light ◽  
Optical Sectioning ◽  
Spatiotemporal Resolution ◽  
Near Infrared Light ◽  
Light Sheet Microscopy ◽  
Non Invasive

AbstractDeep-tissue three-dimensional optical imaging of live mammals in vivo with high spatiotemporal resolution in non-invasive manners has been challenging due to light scattering. Here, we developed near-infrared (NIR) light sheet microscopy (LSM) with optical excitation and emission wavelengths up to ~ 1320 nm and ~ 1700 nm respectively, far into the NIR-II (1000-1700 nm) region for 3D optical sectioning through live tissues. Suppressed scattering of both excitation and emission photons allowed one-photon optical sectioning at ~ 2 mm depth in highly scattering brain tissues. NIR-II LSM enabled non-invasive in vivo imaging of live mice, revealing never-before-seen dynamic processes such as highly abnormal tumor microcirculation, and 3D molecular imaging of an important immune checkpoint protein, programmed-death ligand 1 (PD-L1) receptors at the single cell scale in tumors. In vivo two-color near-infrared light sheet sectioning enabled simultaneous volumetric imaging of tumor vasculatures and PD-L1 proteins in live mammals.

In Vivo Monitoring of Intravenously Injected Gold Nanorods Using Near‐Infrared Light

Small ◽  
2008 ◽  
Vol 4 (7) ◽  
pp. 1001-1007 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Monitoring

Non-invasive neuroimaging using near-infrared light

2002 ◽  
Vol 52 (7) ◽  
pp. 679-693 ◽  
Author(s):  
Gary Strangman ◽  
David A Boas ◽  
Jeffrey P Sutton
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Non Invasive

Near-Infrared Light Emitting Diode Based Non-Invasive Glucose Detection System

2019 ◽  
Vol 19 (10) ◽  
pp. 6187-6191 ◽  
Author(s):  
Seung Ho Lee ◽  
Min Seok Kim ◽  
Ok-Kyun Kim ◽  
Hyung-Hwan Baik ◽  
Ji-Hye Kim
Keyword(s):  
Near Infrared ◽  
Detection System ◽  
Light Emitting Diode ◽  
Infrared Light ◽  
Glucose Detection ◽  
Near Infrared Light ◽  
Light Emitting ◽  
Non Invasive

scholarly journals In vivo performance of near-infrared light transillumination for dentine proximal caries detection in permanent teeth

2020 ◽  
Vol 32 (4) ◽  
pp. 187-193
Author(s):  
Ayşe Dündar ◽  
Mehmet Ertuğrul Çiftçi ◽  
Özlem İşman ◽  
Ali Murat Aktan
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Caries Detection ◽  
Permanent Teeth ◽  
Near Infrared Light ◽  
Proximal Caries

scholarly journals Powering rotary molecular motors with low-intensity near-infrared light

2020 ◽  
Vol 6 (44) ◽  
pp. eabb6165
Author(s):  
Lukas Pfeifer ◽  
Nong V. Hoang ◽  
Maximilian Scherübl ◽  
Maxim S. Pshenichnikov ◽  
Ben L. Feringa
Keyword(s):  
Smart Materials ◽  
Molecular Motors ◽  
Near Infrared ◽  
In Vivo Studies ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Two Photon ◽  
Low Intensity

Light-controlled artificial molecular machines hold tremendous potential to revolutionize molecular sciences as autonomous motion allows the design of smart materials and systems whose properties can respond, adapt, and be modified on command. One long-standing challenge toward future applicability has been the need to develop methods using low-energy, low-intensity, near-infrared light to power these nanomachines. Here, we describe a rotary molecular motor sensitized by a two-photon absorber, which efficiently operates under near-infrared light at intensities and wavelengths compatible with in vivo studies. Time-resolved spectroscopy was used to gain insight into the mechanism of energy transfer to the motor following initial two-photon excitation. Our results offer prospects toward in vitro and in vivo applications of artificial molecular motors.

Near-Infrared Light Dual-Promoted Heterogeneous Copper Nanocatalyst for Highly Efficient Bioorthogonal Chemistry in Vivo

ACS Nano ◽  
2020 ◽  
Vol 14 (4) ◽  
pp. 4178-4187 ◽  
Author(s):  
Yawen You ◽  
Fangfang Cao ◽  
Yajie Zhao ◽  
Qingqing Deng ◽  
Yanjuan Sang ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Bioorthogonal Chemistry ◽  
Near Infrared Light ◽  
Highly Efficient
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