scholarly journals Authorship inflation and author gender in pulmonology research

2018 ◽  
Author(s):  
Blake Umberham ◽  
Caleb Smith ◽  
Nolan Henning ◽  
Matt Vassar
Keyword(s):  
Web Of Science ◽  
Medical Literature ◽  
Median Number ◽  
International Committee ◽  
Primary Objective ◽  
Female Authors ◽  
Honorary Authorship ◽  
And Gender ◽  
Author Position ◽  
Number Of Authors

AbstractIntroductionHonorary authorship and equal gender representation are two pressing matters in scientific research. Honorary authorship is the inclusion of authors who do not meet the criteria established by the International Committee of Medical Journal Editors (ICMJE) authorship guidelines. The inclusion of honorary authors in the medical literature has led to an increase of the number of authors on studies and a decrease in single author studies in various fields.MethodsOur primary objective was to assess authorship trends in two major pulmonology journals (selected on the basis of Google Scholar rankings): Thorax and American Journal of Respiratory and Critical Care Medicine. We reviewed all articles published in both journals in the years 1994, 2004, and 2014 using Web of Science and extracted data such as number of authors and gender of the first and last authors.ResultsThe total number of authors steadily increased from 1994 to 2014. The median number of authors grew from about four in 1994 to nearly seven in 2014, which is approximately a 75% increase. When we compiled all the data, we found the percentage of female authors from both journals had increased from 17% to 29.9% during the study period.DiscussionWe found an increase in the average number of authors on pulmonology publications between 1994 and 2014 as well as an increase in the number of females with a lead or main author position. This may be due to a variety of factors, such as increased team science. However, our data in conjunction with data from other areas of medicine, indicate that honorary authorship may be contributing to the trends we identified.

scholarly journals Disequilibrium in Gender Ratios among Authors who Contributed Equally

2017 ◽  
Author(s):  
Nichole A. Broderick ◽  
Arturo Casadevall
Keyword(s):  
Scientific Publication ◽  
Biomedical Literature ◽  
Fair Share ◽  
Concomitant Increase ◽  
The Past ◽  
And Gender ◽  
Author Position ◽  
Mixed Gender ◽  
Equal Contribution ◽  
Number Of Authors

AbstractIn recent decades, the biomedical literature has witnessed an increasing number of authors per article together with a concomitant increase of authors claiming to have contributed equally. In this study, we analyzed over 3000 publications from 1995–2017 claiming equal contributions for authors sharing the first author position for author number, gender, and gender position. The frequency of dual pairings contributing equally was male-male > mixed gender > female-female. For mixed gender pairs males were more often at the first position although the disparity has lessened in the past decade. Among author associations claiming equal contribution and containing three or more individuals, males predominated in both the first position and number of gender exclusive groupings. Our results show a disequilibrium in gender ratios among authors who contributed equally from expected ratios had the ordering been done randomly or alphabetical. Given the importance of the first author position in assigning credit for a publication, the finding of fewer than expected females in associations involving shared contributions raises concerns about women not receiving their fair share of expected credit. The results suggest a need for journals to request clarity on the method used to decide author order among individuals claiming to have made equal contributions to a scientific publication.

Feminist Shakespeares: Adapting Shakespeare for a Modern Audience in the Hogarth Shakespeare Project

2018 ◽  
Author(s):  
Colleen Etman
Keyword(s):  
Margaret Atwood ◽  
Female Characters ◽  
Adaptation Theory ◽  
Contemporary Culture ◽  
The Winter's Tale ◽  
Winter's Tale ◽  
Female Authors ◽  
The Tempest ◽  
And Gender ◽  
Female Characterization

The Hogarth Shakespeare Project presents a way to view Shakespeare’s plays through a different lens. These books allow for a feminist reading of Shakespeare, looking at some of Shakespeare’s ill-treated female characters to construct a new idea of female characterization. Three of the plays adapted, The Winter’s Tale, The Tempest, and The Taming of the Shrew, were adapted by female authors. By investigating how these plays are being adapted for a more contemporary audience, with modern conceptions of feminism and gender roles, we can gain insight as to how these concepts have changed since Shakespeare’s time. By looking at these modern adaptations, we can interrogate how modern audiences as a whole conceptualize and, potentially, idealize Shakespeare, as well as understanding the progression of treatment of women in contemporary culture since Shakespeare’s time. The novels addressed in this project are The Gap of Time by Jeannette Winterson, Hag-Seed by Margaret Atwood, and Vinegar Girl by Anne Tyler. The project concludes that, of the three, Vinegar Girl does the most effective job addressing the problematic aspects of its adapted play in a new way, distinguishing it from previous adaptations of The Taming of the Shrew. This project also investigates the role that adaptation theory plays in addressing Shakespeare adaptations, particularly the Hogarth Shakespeare Project.

scholarly journals Kinematic variables of table vault on artistic gymnastics

2016 ◽  
Vol 30 (1) ◽  
pp. 97-107
Author(s):  
Sarah Maria Boldrini FERNANDES ◽  
Paulo CARRARA ◽  
Júlio Cerca SERRÃO ◽  
Alberto Carlos AMADIO ◽  
Luis MOCHIZUKI
Keyword(s):  
Web Of Science ◽  
Body Position ◽  
Meta Analysis ◽  
Technical Level ◽  
Male And Female ◽  
The Real ◽  
Technical Performance ◽  
Comprehensive Information ◽  
Applicable Knowledge ◽  
And Gender

Abstract The table vault is an event of male and female Artistics Gymnastics. Although it can be performed in a variety of rotations and body positions in different phases, it can be separated in three groups: handspring, Yurchenko and Tsukahara. It is believed that kinematic variables of vault may vary according to group of vault or gymnast body position, but few studies compares the real differences among the three groups of vaults, comparing and describing the variables in different phases. Vault kinematic variables could be diversifying according to the approach or position of the vaulting, but little has been studied about the biomechanical differences, comparing and describing behaviours at different stages. The aim of this study was to organize critical, objective and to systematize the most relevant kinematic variables to performance on vaulting. A Meta analysis over the basis Pubmed, Sport Discus and Web of Science were performed about this issue. From the selected references, we described and analyzed the kinematics of the table vault. Vault can be characterized in seven phases of analysis. Most of the studies are descriptive, and some do not descript all phases. Differences among vault variables according to group vaults, technical level and gender were analysed only in recent studies. There still gaps of knowledge about kinematic variables of table vault, in order to provide comprehensive information about all possibilities of vaults in this gymnastic event. It is concluded that kinematic variables of table vault depends upon vault group and may be considered to the improvement of technical performance. More researches are needed to approach the coaching interface with biomechanics applicable knowledge.

scholarly journals Short term momentum profits and their source: a business indicators’ approach

2013 ◽  
Vol 59 (No. 12) ◽  
pp. 563-577
Author(s):  
A. Ejaz ◽  
P. Polak
Keyword(s):  
Stock Markets ◽  
Primary Objective ◽  
Future Research ◽  
Momentum Effect ◽  
Short Term ◽  
Momentum Profits ◽  
The Future ◽  
Secondary Objective ◽  
Number Of Authors ◽  
Starting A Business

The main objective of the paper is to seek the source that can explain the momentum profits because the source of momentum profits has been disputed. The secondary objective of the paper is to affirm the findings of the author about the presence of the short term momentum effect and to reaffirm the notion that CAPM cannot explain the momentum profits supported by a large number of authors. For the primary objective, a set of variables has been chosen, that fall under the category of “Business Indicators”, to explain the momentum profits. It is found that a variable “Starting a Business” could explain the source of the momentum profits whereas other variables may have a negligible or no influence over the momentum profits. It is also reaffirmed that a short term momentum effect has been found in 14 stock markets and the CAPM could not explain the momentum profits. This study is not conclusive due to the limitation of data but it does give a source of the momentum profits and it sheds light on the future research about the sources that can explain momentum profits in a great detail.

scholarly journals Self-skincare knowledge and practice described by elderly persons in the mid-west of Minas Gerais

2016 ◽  
Vol 19 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Juliana Ladeira Garbaccio ◽  
Amanda Domingos Ferreira ◽  
Amanda Laís Gonçalves Gama Pereira
Keyword(s):  
The Elderly ◽  
Median Number ◽  
Cross Sectional Study ◽  
Skin Aging ◽  
Minas Gerais ◽  
Sample Population ◽  
Elderly Persons ◽  
Cross Sectional ◽  
Basic Care ◽  
And Gender

The present study aimed to assess the knowledge and practices reported by the elderly in relation to basic care of one's skin. A cross sectional study was performed from November 2011 to August 2012 in Arcos, Minas Gerais, based on a structured questionnaire administered to 250 elderly persons, with answers statistically analyzed. Knowledge and practices of self-skincare were evaluated from the median number of ten questions answered by the elderly. Most of the sample population were women (54.8%), aged between 60 and 69 years (52.4%), with a primary education (71.6%) and working in a job where they were exposed to direct sunlight (58.0%). The majority (76.4%) said they did not use protective sun filter despite considering it important (77.6%). The use of body moisturizing creams was reported by 55.6%. An association (p<0.05) was identified between the variables practice/knowledge and gender and practice outdoor activity. Further studies can be conducted as a result of the present research to clarify factors related to non-adherence to self-skincare, and educational measures should be put in place for the entire population, regardless of age, to prevent pathological skin aging.

‘Female Nectar’: A Study of Hybridity and Gender in Contemporary Tibetan Medical Literature on Menstruation

2012 ◽  
Vol 6 (2) ◽  
pp. 387-420 ◽  
Author(s):  
Jenny Bright
Keyword(s):  
Medical Literature ◽  
Medical Knowledge ◽  
Tibetan Medicine ◽  
Biomedical Knowledge ◽  
Women And Gender ◽  
Cultural Perceptions ◽  
And Gender ◽  
Key Aspects ◽  
Medical Writers

Abstract This essay examines contemporary Tibetan medical literature that deals with menstruation, focusing on the relations among medical, religious and cultural perceptions of women and gender. Present-day medical writers present a hybrid account of menstruation, incorporating key aspects of Tibetan medicine, such as the refining processes of digestion and the red element, with biomedical knowledge, notably the role of hormones. The integration of biomedical thought by Tibetan writers works to substantiate and bolster the validity of Tibetan medical claims, rather than discredit them. Consequently, contemporary writers are able to articulate medical knowledge about women that is as much about Tibetan religious and cultural perceptions of gender and sexed-bodies, as it is ‘scientific’.

Safety and efficacy of the anti-CD73 monoclonal antibody (mAb) oleclumab ± durvalumab in patients (pts) with advanced colorectal cancer (CRC), pancreatic ductal adenocarcinoma (PDAC), or EGFR-mutant non-small cell lung cancer (EGFRm NSCLC).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 9047-9047
Author(s):  
Johanna C. Bendell ◽  
Patricia LoRusso ◽  
Michael J. Overman ◽  
Anne M. Noonan ◽  
Dong-Wan Kim ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Objective Response ◽  
Median Number ◽  
Primary Objective ◽  
Ductal Adenocarcinoma ◽  
Clinical Activity ◽  
Expansion Phase ◽  
Human Dose ◽  
Local Immunosuppression ◽  
Grade 3

9047 Background: Upregulation of CD73 in multiple cancers increases adenosine production, leading to local immunosuppression. Oleclumab, a human IgG1λ mAb, inhibits CD73 function and may increase antitumor immunity. Initial data from a Phase I, first-in-human, dose-escalation and expansion study showed that oleclumab ± durvalumab had manageable safety and encouraging clinical activity in pts with advanced CRC or PDAC. We report updated safety and activity in these cohorts and the first results in an expansion cohort of pts with advanced EGFRm NSCLC. Methods: Previously treated pts with histologically or cytologically confirmed microsatellite stable CRC, PDAC, or EGFRm NSCLC received oleclumab 5–40 mg/kg (escalation) and 40 mg/kg (expansion) IV Q2W, alone (escalation only) or with durvalumab 10 mg/kg IV Q2W. The primary objective was safety; secondary efficacy objectives included objective response (OR) per RECIST v1.1 and duration of response (DoR). Results: 66 pts were enrolled in the escalation phase (35 CRC, 31 PDAC) and 126 in the expansion phase (42 CRC, 42 PDAC, 42 EGFRm NSCLC). At data cutoff (DCO; June 9, 2020), the median number of oleclumab doses was 4 in pts on monotherapy (range 1–26) and 4 in pts on combination therapy across both phases (range 1–76). In the escalation phase, there were no DLTs in pts on monotherapy or combination therapy; treatment-related adverse events (TRAEs) occurred in 54.8% of pts on monotherapy (Grade 3–4 in 7.1%) and 54.2% of pts on combination therapy (Grade 3–4 in 20.8%); fatigue was the most common TRAE with both regimens. No TRAEs resulted in death. In previous interim analyses before this DCO, no ORs were reported in the escalation phase. In the expansion phase, 5 pts were treated for ≥12 mos; 6 pts were ongoing at DCO. TRAEs occurred in 54.0% (Grade 3–5 in 15.1%); the most common TRAEs were fatigue (15.1%), diarrhea (9.5%), and rash (7.1%). One pt had a TRAE resulting in death (systemic inflammatory response syndrome). ORs were seen in 1 CRC pt (DoR 35.9+ mos [+ = ongoing response]), 2 PDAC pts (DoR 22.1+ and 28.6+ mos), and 4 EGFRm NSCLC pts (DoR range 5.6 to 15.7+ mos, median not reached; only 1 of the 4 pts had ≥25% programmed cell death ligand-1 [PD-L1]+ tumor cells). Nine CRC pts, 8 PDAC pts, and 9 EGFRm NSCLC pts had SD. Of 6 pts with matched biopsies who received combination therapy, 5 had increases in CD8+ T cells, PD-L1, and granzyme B. Baseline tumor CD73 expression and association with clinical response will be presented. Conclusions: Oleclumab ± durvalumab had a tolerable safety profile and combination therapy showed promising antitumor activity in EGFRm NSCLC. ORs and SD were durable, even in tumor types that are generally immunotherapy-resistant. Clinical trial information: NCT02503774.

scholarly journals Phase I clinical trial of the combination of eribulin and everolimus in patients with metastatic triple-negative breast cancer

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Jin Sun Lee ◽  
Susan E. Yost ◽  
Suzette Blanchard ◽  
Daniel Schmolze ◽  
Hongwei Holly Yin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Phase I ◽  
Dose Level ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Median Number ◽  
Primary Objective ◽  
Best Response ◽  
Grade 3 ◽  
Number Of Cycles

Abstract Background Alteration of the PI3K/AKT/mTOR pathway is a common genomic abnormality detected in triple-negative breast cancer (TNBC). Everolimus acts synergistically with eribulin in TNBC cell lines and xenograft models. This phase I trial was designed to test the safety and tolerability of combining eribulin and everolimus in patients with metastatic TNBC. Methods The primary objective of this study was to evaluate the safety and toxicities of the combination. Patients with metastatic TNBC who had up to four lines of prior chemotherapies were enrolled. The combination of eribulin and everolimus was tested using three dosing levels: A1 (everolimus 5 mg daily; eribulin 1.4 mg/m2 days 1 and 8 every 3 weeks), A2 (everolimus 7.5 mg daily; eribulin 1.4 mg/m2, days 1 and 8 every 3 weeks), and B1 (everolimus 5 mg daily; eribulin 1.1 mg/m2 days 1 and 8 every 3 weeks). Results Twenty-seven patients with median age 55 years were enrolled. Among 8 evaluable patients who received dose level A1, 4 had dose-limiting toxicities (DLTs). Among 3 evaluable patients treated with dose level A2, 2 had DLTs. Among 12 evaluable patients who received dose level B1, 4 had DLTs. The DLTs were neutropenia, stomatitis, and hyperglycemia. Over the study period, 59% had a ≥ grade 3 toxicity, 44% had ≥ grade 3 hematologic toxicities, and 22% had grade 4 hematologic toxicities. The most common hematological toxicities were neutropenia, leukopenia, and lymphopenia. Thirty-three percent had grade 3 non-hematologic toxicities. The most common non-hematological toxicities were stomatitis, hyperglycemia, and fatigue. The median number of cycles completed was 4 (range 0–8). Among 25 eligible patients, 9 patients (36%) achieved the best response as partial response, 9 (36%) had stable disease, and 7 (28%) had progression. The median time to progression was 2.6 months (95% CI [2.1, 4.0]), and median overall survival (OS) was 8.3 months (95% CI [5.5, undefined]). Conclusion Eribulin 1.1 mg/m2 days 1 and 8 every 3 weeks with everolimus 5 mg daily was defined as the highest dose with acceptable toxicity (RP2D). The combination is safe, and efficacy is modest. A post hoc analysis showed that participants that used dexamethasone mouthwash stayed on treatment for one additional cycle. Trial registration ClinicalTrials.gov, NCT02120469. Registered 18 April 2014

scholarly journals Variables psicológicas asociadas a la corrupción: una revisión sistemática

2020 ◽  
Vol 36 (2) ◽  
pp. 330-339 ◽  
Author(s):  
Martín Julián ◽  
Tomás Bonavia
Keyword(s):  
Web Of Science ◽  
Cultural Beliefs ◽  
Empirical Support ◽  
Psychological Variables ◽  
Political Issues ◽  
Organizational Variables ◽  
Revisión Sistemática ◽  
Bibliographic Search ◽  
And Gender ◽  
Personality Features

En la actualidad, la corrupción constituye uno de los principales problemas psicológicos, sociales, económicos y políticos a nivel mundial. El objetivo del presente estudio es analizar las variables psicológicas asociadas a la corrupción a través de una revisión sistemática de las publicaciones entre 2008 y 2018. Tras realizar una búsqueda en las bases de datos Psycinfo, Web of Science y Dialnet, se encontraron 41 artículos que cumplían con los criterios de selección propuestos. Los grandes núcleos encontrados fueron la ética organizacional, creencias y valores culturales, moral y normas percibidas, y personalidad y variables relacionadas. En general, los resultados apuntan a que variables organizacionales como la percepción de la conducta de sus dirigentes o las estrategias de justificación están relacionadas con la corrupción. Valores culturales meritocráticos y materialistas también han sido ligados a la conducta corrupta, como ocurre en el caso de la percepción de un entorno corrupto y de las normas sociales. En cuanto a la personalidad, rasgos como el narcisismo y la psicopatía se encuentran íntimamente ligados a este fenómeno. Por otra parte, variables como la percepción del poder o el sexo de los participantes han recibido un sustento empírico ambiguo. Nowadays, corruption is one of the most important psychological, social, economic and political issues worldwide. The present paper aims to analyse psychological variables related to corruption through a systematic review of publications from 2008 to 2018. After carrying out a bibliographic search in scientific databases such as Psycinfo, Web of Science and Dialnet, 41 papers were found to match selection criteria. Core topics haven been organizational ethics, cultural beliefs and values, perceived norms and moral, and personality and related variables. Overall, results have shown that organizational variables such as leaders’ behaviour and justification strategies are linked to corruption. Meritocratic and materialist values have also been linked to corrupt behaviour, just like perceiving a corrupt environment and social norms. In regard to personality, features such as narcissism and psychopathy are deeply connected with this phenomenon. On the other side, perception of power and gender have a mixed empirical support.

scholarly journals Uso do telefone para adesão de pessoas vivendo com HIV/AIDS à terapia antirretroviral: revisão sistemática

2019 ◽  
Vol 24 (9) ◽  
pp. 3407-3416
Author(s):  
Vanessa da Frota Santos ◽  
Ana Karoline Bastos Costa ◽  
Ivana Cristina Vieira de Lima ◽  
Herta de Oliveira Alexandre ◽  
Elucir Gir ◽  
...  
Keyword(s):  
Retrieval System ◽  
Web Of Science ◽  
Medical Literature ◽  
Cell Phones ◽  
Literature Analysis ◽  
Highly Active ◽  
Acquired Immunodeficiency ◽  
Terapia Antirretroviral ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

Resumo O objetivo deste artigo é avaliar a eficácia do uso do telefone para adesão de pessoas com HIV/AIDS à terapia antirretroviral. Realizou-se uma revisão sistemática, nas bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs/Bireme), Scopus, Medical Literature Analysis and Retrieval System Online (Medline/PubMed), Web of Science; e nas bibliotecas Scientific Eletronic Library Online (SciELO) e Cochrane, com uso dos seguintes descritores: “HIV”, “Cell Phones”, “Acquired Immunodeficiency Syndrome” e “Antiretroviral Therapy, Highly Active”. Obteve-se uma amostra de 17 artigos. As intervenções com uso de telefones celulares propostas foram: uso de aplicativos de celulares, Serviço de Mensagem Curta e chamadas telefônicas. Na maioria dos estudos, o uso do telefone trouxe impacto significativo sobre a adesão ao tratamento. A avaliação dos estudos apontou boa qualidade metodológica e sigilo de alocação adequado. Acerca dos métodos de mensuração da adesão destacou-se a autorrelatada. A utilização de telefone celular foi eficaz para a melhoria da adesão à terapia antirretroviral de pessoas vivendo com HIV.

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