scholarly journals Accordion-like collagen fibrils suggested by P-SHG image modeling : implication in liver fibrosis

2018 ◽  
Author(s):  
D. Rouède ◽  
E. Schaub ◽  
J-J. Bellanger ◽  
F. Ezan ◽  
F. Tiaho
Keyword(s):  
Liver Fibrosis ◽  
Shot Noise ◽  
Detection System ◽  
A Priori ◽  
Anisotropy Parameter ◽  
Image Modeling ◽  
Mechanical Stiffness ◽  
Molecular Hyperpolarizability ◽  
Collagen Molecules ◽  
Tensor Element

ABSTRACTSecond-order non-linear optical anisotropy parameter ρ = χ33 / χ31 is calculated for collagen-richt issues considering both a single dominant molecular hyperpolarizability tensor element β333 = β at single helix level and a priori known submicrometric triple helical organization of collagen molecules. Modeling is further improved by taking account of Poisson photonic shot noise of the detection system and simple supra-molecular fibrillar arrangements in order to accurately simulate the dispersion of ρ values in collagen-rich tissues such as tendon, skin and liver vessels. From combined P-SHG experiments and modeling, we next correlate experimental and theoretical statistical distributions of ρ. Our results highlight that the dispersion of experimental ρ values is mainly due to (i) Poisson photonic shot noise in tendon and skin, which proves to have a preponderant effect in P-SHG experiments (ii) variance of supercoil angles of accordion-like fibrils in vessels that is further reduced during the development of liver fibrosis therefore contributing to the rigidity of the tissue. These results open new avenue for future modeling correlating the dispersion of ρ values in P-SHG experiments and the fibrillar architecture as well as the mechanical stiffness of patho-physiological extracellular matrices in collagen tissues.

scholarly journals TDMR Detection System with Local Area Influence Probabilistic a Priori Detector

2019 ◽  
Author(s):  
Jinlu Shen ◽  
Xueliang Sun ◽  
Krishnamoorthy Sivakumar ◽  
Benjamin J. Belzer ◽  
Kheong Sann Chan ◽  
...  
Keyword(s):  
Detection System ◽  
A Priori ◽  
Local Area

Multiscale Modeling of Nafion Mechanical Properties

2009 ◽  
Author(s):  
Ursula T. Zangrilli ◽  
Lisa M. Weiland
Keyword(s):  
Multiscale Modeling ◽  
A Priori ◽  
Ionic Polymers ◽  
Mechanical Stiffness ◽  
Response Strategies ◽  
Rotational Isomeric State ◽  
Material Stiffness ◽  
Electromechanical Transduction ◽  
Chain Lengths ◽  
The Impact

Multiscale modeling is used to investigate the mechanical characteristics of ionic polymers with the intent of ultimately expanding understanding of the interplay between multiscale stiffness and electromechanical response. Strategies for manipulating electromechanical transduction of ionic polymers include, but are not limited to: variation of hydration and/or the equivalent weight. In general, variations resulting in increased electroactive response also result in decreased mechanical stiffness and can decrease to the point of limiting mechanical integrity. This effort begins with the supposition that a better understanding of the ionic polymer multiscale material stiffness will enable bypass of this perceived trade-off. Rotational Isomeric State (RIS) theory is used to predict the conformation of a typical polymer hydrophobic backbone for a fully hydrated, sodium exchanged, Nafion 1200 EW case. The RIS method generates a large number of crosslink-to-crosslink chain lengths. The distribution is assessed via Johnson distributions and in turn, employed in a Boltzmann statistical thermodynamics framework to assess mechanical stiffness. The approach explores the impact of morphology on stiffness via imposing as assumed morphology a priori.

Based on the Human Eye Fatigue Detection System of Recognition and FPGA Technology

2014 ◽  
Vol 672-674 ◽  
pp. 1995-1998 ◽  
Author(s):  
Jun Wang ◽  
Qiang Liu ◽  
Hang Zhao
Keyword(s):  
High Speed ◽  
Detection System ◽  
A Priori ◽  
Color Space ◽  
Gaussian Model ◽  
Region Growing ◽  
Detection Algorithm ◽  
Detection Accuracy ◽  
Threshold Detection ◽  
Human Eye

This paper introduces the field programmable gate array (fpga) application in high-speed visual inspection system.ALTERA EP1K30QC208-2 are used in the system for system calculation and control of the core, to perform high-speed real-time visual detection algorithm, this paper adopts a yawning based on eye closure and to detect driver fatigue, the method of in YCr, Cb in the color space using gaussian model skin detection of human face area, in the face of a gray binarization figure using a priori knowledge of facial features geometry in rough positioning the human eye, eye contour are obtained by region growing and morphological operation and calculation of the closure of the eye;Best threshold detection lips when using lip color roughly locate the lips, on the basis of accurate positioning lips by face grey value characteristics, and then through the mouth level to determine whether a driver yawn;Based on the two characteristics of driving fatigue, experiments show that this system detection speed, excellent versatility, and can improve the detection accuracy.

SPIN-DEPENDENT SHOT NOISE IN APERIODIC SEMICONDUCTOR MULTILAYERS HETEROSTRUCTURES

2012 ◽  
Vol 26 (30) ◽  
pp. 1250200
Author(s):  
AILI QIN ◽  
DE LIU
Keyword(s):  
Electric Field ◽  
Shot Noise ◽  
Detection System ◽  
Electronic Devices ◽  
Fano Factor ◽  
Orbit Interaction ◽  
Spin Orbit ◽  
Spin Orbit Interaction ◽  
External Bias ◽  
Rashba Spin

We investigated the spin-dependent shot noise in aperiodic semiconductor multilayers heterostructures in the presence of the Rashba spin-orbit interaction and an electric field. The results indicate that the shot noise and Fano factor are strongly spin-dependent and can be greatly modulated not only by the external bias voltage and Rashba spin-orbit interaction but also by the thicknesses of block A and B. Our investigations may provide away to design the detection system electronic devices.

Application of ert method for identification of electric anisotropy in the Kluchi field area

2020 ◽  
Author(s):  
Aleksandr E. Shalaginov ◽  
◽  
Nina N. Nevedrova ◽  
Aidisa M. Sanchaa ◽  
Ilya O. Shaparenko ◽  
...  
Keyword(s):  
A Priori ◽  
Anisotropy Parameter ◽  
Environmental Problems ◽  
Nature Management ◽  
Electrical Tomography ◽  
Geoelectric Model ◽  
Electric Anisotropy ◽  
Well Data ◽  
Field Area ◽  
Exploration And Development

The article presents the results of the measurements by electrical tomography methods in the area of the Kluchi polygon. Taking into account a priori well data, the parameters of the geoelectric model and the anisotropic characteristics of the reference geoelectric horizon, represented by shale, are determined. The anisotropy parameter can be used in priority tasks of nature management for the exploration and development of minerals, in environmental problems, to prevent dangerous natural and man–made phenomena.

Development of Prototype Video-Based Sensor for Vehicle Detection from Stand-Still Images

1997 ◽  
Vol 1570 (1) ◽  
pp. 202-210
Author(s):  
Anthony Tzes ◽  
William R. McShane
Keyword(s):  
Detection System ◽  
A Priori ◽  
Vehicle Detection ◽  
Field Studies ◽  
Wide Area ◽  
Prototype System ◽  
Design Development ◽  
Still Images ◽  
Observation Area ◽  
Traffic Detection

The design, development, and testing of a prototype wide-area traffic detection system are described. The video-based sensor computes the approximate number of vehicles present within an a priori defined observation area from stand-still images. This sensor is mostly oriented toward the traffic detection in congested intersections, in which sensors using existing radar, acoustic, and video-based technology are faced with critical obstacles caused by the automobile stoppage. The prototype system has been tested and found to perform satisfactorily in field studies.

Analysis of electron-diffraction intensity profiles using a photodiode-array detection system

1983 ◽  
Vol 41 ◽  
pp. 322-323
Author(s):  
J. B. Warren
Keyword(s):  
Electron Diffraction ◽  
Diffraction Pattern ◽  
Detection System ◽  
High Energy ◽  
Photographic Emulsion ◽  
Diffraction Intensity ◽  
Silicon Photodiode ◽  
Photodiode Array Detection ◽  
Analog To Digital ◽  
Photodiode Array

Electron diffraction intensity profiles have been used extensively in studies of polycrystalline and amorphous thin films. In previous work, diffraction intensity profiles were quantitized either by mechanically scanning the photographic emulsion with a densitometer or by using deflection coils to scan the diffraction pattern over a stationary detector. Such methods tend to be slow, and the intensities must still be converted from analog to digital form for quantitative analysis. The Instrumentation Division at Brookhaven has designed and constructed a electron diffractometer, based on a silicon photodiode array, that overcomes these disadvantages. The instrument is compact (Fig. 1), can be used with any unmodified electron microscope, and acquires the data in a form immediately accessible by microcomputer.Major components include a RETICON 1024 element photodiode array for the de tector, an Analog Devices MAS-1202 analog digital converter and a Digital Equipment LSI 11/2 microcomputer. The photodiode array cannot detect high energy electrons without damage so an f/1.4 lens is used to focus the phosphor screen image of the diffraction pattern on to the photodiode array.

Data Acquisition and Handling Unit for a Quantitative Use of Electron Energy Loss Spectroscopy

1977 ◽  
Vol 35 ◽  
pp. 232-233 ◽  
Author(s):  
P. Trebbia ◽  
P. Ballongue ◽  
C. Colliex
Keyword(s):  
Electron Microscope ◽  
Energy Loss ◽  
Electron Energy ◽  
Electron Energy Loss Spectroscopy ◽  
Single Channel ◽  
Detection System ◽  
Surface Barrier ◽  
Solid State Detector ◽  
Electrostatic Mirror ◽  
Electron Energy Loss

An effective use of electron energy loss spectroscopy for chemical characterization of selected areas in the electron microscope can only be achieved with the development of quantitative measurements capabilities.The experimental assembly, which is sketched in Fig.l, has therefore been carried out. It comprises four main elements.The analytical transmission electron microscope is a conventional microscope fitted with a Castaing and Henry dispersive unit (magnetic prism and electrostatic mirror). Recent modifications include the improvement of the vacuum in the specimen chamber (below 10-6 torr) and the adaptation of a new electrostatic mirror.The detection system, similar to the one described by Hermann et al (1), is located in a separate chamber below the fluorescent screen which visualizes the energy loss spectrum. Variable apertures select the electrons, which have lost an energy AE within an energy window smaller than 1 eV, in front of a surface barrier solid state detector RTC BPY 52 100 S.Q. The saw tooth signal delivered by a charge sensitive preamplifier (decay time of 5.10-5 S) is amplified, shaped into a gaussian profile through an active filter and counted by a single channel analyser.

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