scholarly journals Analysis and comparison of genome editing using CRISPResso2

2018 ◽  
Author(s):  
Kendell Clement ◽  
Holly Rees ◽  
Matthew C. Canver ◽  
Jason M. Gehrke ◽  
Rick Farouni ◽  
...  
Keyword(s):  
Genome Editing ◽  
Deep Sequencing ◽  
Sequencing Data ◽  
Editing Efficiency ◽  
Deep Sequencing Data ◽  
Allele Specific

AbstractGenome editing technologies are rapidly evolving, and analysis of deep sequencing data from target or off-target regions is necessary for measuring editing efficiency and evaluating safety. However, no software exists to analyze base editors, perform allele-specific quantification or that incorporates biologically-informed and scalable alignment approaches. Here, we present CRISPResso2 to fill this gap and illustrate its functionality by experimentally measuring and analyzing the editing properties of six genome editing agents.

scholarly journals GenomeGems: evaluation of genetic variability from deep sequencing data

2012 ◽  
Vol 5 (1) ◽  
pp. 338
Author(s):  
Sharon Ben-Zvi ◽  
Adi Givati ◽  
Noam Shomron
Keyword(s):  
Genetic Variability ◽  
Deep Sequencing ◽  
Sequencing Data ◽  
Deep Sequencing Data

Considering DNA damage when interpreting mtDNA heteroplasmy in deep sequencing data

2017 ◽  
Vol 26 ◽  
pp. 1-11 ◽  
Author(s):  
Molly M. Rathbun ◽  
Jennifer A. McElhoe ◽  
Walther Parson ◽  
Mitchell M. Holland
Keyword(s):  
Dna Damage ◽  
Deep Sequencing ◽  
Sequencing Data ◽  
Deep Sequencing Data

scholarly journals Analyzing the microRNA Transcriptome in Plants Using Deep Sequencing Data

Biology ◽  
2012 ◽  
Vol 1 (2) ◽  
pp. 297-310 ◽  
Author(s):  
Xiaozeng Yang ◽  
Lei Li
Keyword(s):  
Deep Sequencing ◽  
Sequencing Data ◽  
Deep Sequencing Data

scholarly journals Discovery of Novel Human Breast Cancer MicroRNAs from Deep Sequencing Data by Analysis of Pri-MicroRNA Secondary Structures

PLoS ONE ◽  
2011 ◽  
Vol 6 (2) ◽  
pp. e16403 ◽  
Author(s):  
Seongho Ryu ◽  
Natasha Joshi ◽  
Kevin McDonnell ◽  
Jongchan Woo ◽  
Hyejin Choi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Deep Sequencing ◽  
Human Breast Cancer ◽  
Secondary Structures ◽  
Human Breast ◽  
Sequencing Data ◽  
Deep Sequencing Data

Noncoding RNA: Current Deep Sequencing Data Analysis Approaches and Challenges

2016 ◽  
Vol 37 (12) ◽  
pp. 1283-1298 ◽  
Author(s):  
Dario Veneziano ◽  
Sebastiano Di Bella ◽  
Giovanni Nigita ◽  
Alessandro Laganà ◽  
Afredo Ferro ◽  
...  
Keyword(s):  
Data Analysis ◽  
Deep Sequencing ◽  
Noncoding Rna ◽  
Sequencing Data ◽  
Deep Sequencing Data ◽  
Sequencing Data Analysis

Deep Sequencing Data Analysis

2018 ◽  
Vol 15 (2) ◽  
pp. 482-483
Author(s):  
Bijoy K. Ghosh ◽  
Aniruddha Datta ◽  
Ranadip Pal
Keyword(s):  
Data Analysis ◽  
Deep Sequencing ◽  
Sequencing Data ◽  
Deep Sequencing Data ◽  
Sequencing Data Analysis
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