scholarly journals A novel bioactive molecule 5-β-Hydroxyltridecanyl benzoate identified in Pedalium Murex L. (Gokhru) fruit extracts showed antifungal activity against Sclerotinia sclerotiorum

2018 ◽  
Author(s):  
Gulshan Chaudhary ◽  
Nutan Kaushik ◽  
Pallavolu Maheswara Reddy

AbstractFruits of Pedalium murex known as, ‘Gokhru’ is predominantly used in Ayurveda for its aphrodisiac properties and use in treatment of urological orders. However till now, bioactivity of this fruit has not been documented for plant protection against phytopathogenes, Hence in this regard, we investigated antimicrobial activity of P. murex fruit extracts (isolated from the different agro climatic zones of India) were tested against twelve microbial phytopathogens. From 29 fruit extracts, only 13 were found to be active against three pathogens viz. Botrytis cinerea, Rhizoctonia solani, and Sclerotinia sclerotiorum. Among the nine TLC fractions only one showed presence of a single peak, thus presence of a single compound in the crude extract. Based on lower IC50 value (328 μg/ml) the crude fruit extract collected from Indore region was further characterized. Evaluation against screened phytopathogens indicates its activity. Further, structural characterization of this compound using FTIR and NMR revealed it to be a novel compound i.e. 5-β-Hydroxyl tridecanyl benzoate. Our study paves a way to investigate effective dose of P. murex fruit extracts to utilize in plant protection programs. In future, a better method is required to scale up the process of bioactive molecule (5-β-Hydroxyl tridecayl benzoate) extraction from P. murex or for its chemical synthesis.

Molecules ◽  
2020 ◽  
Vol 25 (20) ◽  
pp. 4735
Author(s):  
Maša Knez Hrnčič ◽  
Darija Cör ◽  
Jana Simonovska ◽  
Željko Knez ◽  
Zoran Kavrakovski ◽  
...  

Phytochemical research based on ethnopharmacology is gaining interest in industries such as functional food, nutraceuticals, cosmetics and pharmaceutical industries. Plants and plant extracts are a rich source of bioactive secondary metabolites. These compounds are often involved in plant protection against biotic or abiotic stresses. The exploitation of available technologies should be oriented and intensified to extend and enhance the continued usefulness of the plants as renewable sources of chemicals, especially medicinal compounds. This current contribution is focused on extraction and analytical techniques for their isolation from the oregano species, their characterization and their potential antioxidative, as well as their antimicrobial, antifungal and anticarcinogenic properties. The work is structured rendering to the different steps involved in the research; starting with extraction and sample preparation, followed by discussing the analytical techniques employed for the isolation and identification of compound/s responsible for the biological activity and methods and techniques for biological activity assessment.


2004 ◽  
Vol 41 (8) ◽  
pp. 754-765 ◽  
Author(s):  
Rugang Li ◽  
Roger Rimmer ◽  
Lone Buchwaldt ◽  
Andrew G Sharpe ◽  
Ginette Séguin-Swartz ◽  
...  

2016 ◽  
Vol 219 ◽  
pp. 92-99 ◽  
Author(s):  
Kunfei Li ◽  
Dan Zheng ◽  
Jiasen Cheng ◽  
Tao Chen ◽  
Yanping Fu ◽  
...  

Author(s):  
Md. Rabiul Islam ◽  
Abdul Mannan Akanda ◽  
Md. Mofazzal Hossain ◽  
Md. Motaher Hossain

Author(s):  
Sajib Aninda Dhar ◽  
Rashedul Alam Chowdhury ◽  
Shaon Das ◽  
Md. Khalid Nahian ◽  
Dipa Islam ◽  
...  

Author(s):  
Jichun Jia ◽  
Fan Mu ◽  
Yanping Fu ◽  
Jiasen Cheng ◽  
Yang Lin ◽  
...  

Author(s):  
Viral K. Patel ◽  
Frederick Kyle Reed ◽  
Roger Kisner ◽  
Chang Peng ◽  
Saeed Moghaddam ◽  
...  

Abstract Fabric drying is an energy-intensive process, which generally involves blowing hot dry air across tumbling wet fabric to facilitate evaporation and moisture removal. Most of the energy supplied is used to overcome the enthalpy of vaporization for water. Although this process tends to be inefficient, it is fairly simple and forms the basis for the majority of existing clothes dryer technology today. To address the relatively low efficiency, a new method of drying called “direct contact ultrasonic fabric drying” is proposed. The process involves using high-frequency vibration introduced by piezoelectric transducers, which are in contact with wet fabric. The vibration is used to extract water droplets from the fabric mechanically. In this study, a total of 24 individual transducers are used in a module to dry a 142 cm2 sized fabric. The performance characterization of this single module has enabled successful scale-up of the system to a midscale prototype dryer, which can be used to ultrasonically dry clothing-sized fabric (∼750 cm2). The first-generation ultrasonic fabric dryer fabricated uses as little as 17% of the energy needed by traditional evaporation-based drying techniques. In addition to experimental data, this paper presents the results of a kinetic and scaling analysis that provides some important insights into ultrasonic drying.


2019 ◽  
Vol 54 (1) ◽  
pp. 96-111
Author(s):  
Guilherme Fowler A. Monteiro

Purpose This paper aims to conduct an extensive review and advances a framework for the literature of high-growth firms (HGFs) and scale-ups. Design/methodology/approach This paper takes the form of a literature review. Findings The author makes three specific contributions. First, he presents a broad review of high growth in firms, shedding light on the different levels of analysis. Second, he advances a characterization of scale-up companies to enable a better basis for discussion. Finally, he identifies gaps in the existing literature and suggest paths for future research. Originality/value The interest in HGFs and those referred to as scale-ups has increased considerably in recent years. Despite this trend, existing studies still have conceptual divergences and a gap separating theoretical inputs from the actual experiences of entrepreneurs.


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