scholarly journals The Brain/MINDS 3D digital marmoset brain atlas

2017 ◽  
Author(s):  
Alexander Woodward ◽  
Tsutomu Hashikawa ◽  
Masahide Maeda ◽  
Takaaki Kaneko ◽  
Keigo Hikishima ◽  
...  

AbstractWe present a new 3D digital brain atlas of the non-human primate, common marmoset monkey (Callithrix jacchus), with MRI and coregistered Nissl histology data. To the best of our knowledge this is the first comprehensive digital 3D brain atlas of the common marmoset having normalized multi-modal data, cortical and sub-cortical segmentation, and in a common file format (NIfTI). The atlas can be registered to new data, is useful for connectomics, functional studies, simulation and as a reference.The atlas was based on previously published work but we provide several critical improvements to make this release valuable for researchers. Nissl histology images were processed to remove illumination and shape artifacts and then normalized to the MRI data. Brain region segmentation is provided for both hemispheres. The data is in the NIfTI format making it easy to integrate into neuroscience pipelines, whereas the previous atlas was in an inaccessible file format. We also provide cortical, mid-cortical and white matter boundary segmentations useful for visualization and analysis.

2012 ◽  
Vol 210 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Enrique Garea-Rodríguez ◽  
Christina Schlumbohm ◽  
Boldizsár Czéh ◽  
Jessica König ◽  
Gunther Helms ◽  
...  

2009 ◽  
Vol 62 (1) ◽  
pp. 1-18 ◽  
Author(s):  
John D. Newman ◽  
William M. Kenkel ◽  
Emily C. Aronoff ◽  
Nicholas A. Bock ◽  
Molly R. Zametkin ◽  
...  

2011 ◽  
Vol 411 (2) ◽  
pp. 317-322 ◽  
Author(s):  
Inga Bernemann ◽  
Thomas Mueller ◽  
Rainer Blasczyk ◽  
Birgit Glasmacher ◽  
Nicola Hofmann

Reproduction ◽  
2009 ◽  
Vol 137 (3) ◽  
pp. 517-525 ◽  
Author(s):  
Christina Simon ◽  
Almuth Einspanier

Controversy still exists regarding the involvement of relaxin (RLX) in cervical reorganization throughout parturition in the human, despite its well-known role in facilitating extensive extracellular matrix (ECM) remodeling in diverse organs. Therefore, the aim of the present study was to examine the influence of RLX and estrogen (E2) on the cervical tissue of the common marmoset monkey. Two experimental designs were used: 1)in vivoanalysis of the intracervical diameter under locally applied RLX and 2) ovariectomized (ov) marmosets were treated systemically with either recombinant human (rh) RLX, E2 or rhRLX+E2 to examine their action on the cervix.In vivo-locally applied rhRLX induced a distinct and significant widening of the cervix (before: 4.8±1.1 mm versus after: 5.7±0.9 mm in diameter;P<0.030, MV±s.e.m.). This widening effect was most pronounced in animals without previous pregnancies.In vitroinvestigation of cervical tissue showed significantly increased wet weights after all three hormone treatments (E2: 0.27±0.07 g, RLX: 0.25±0.04 g, E2+RLX: 0.30±0.11 g; allP<0.05; MV±s.e.m.) versus controls (0.10±0.04 g). Furthermore, morphological changes such as loosening of the connective tissue structure and decline in collagen content, an increase in the number of eosinophils, increased the expression of matrix metalloproteinases (MMP1) and MMP2, as well as gene and protein expression of the RLX receptor RXFP1 could be detected in the cervical tissue after all hormone treatments, compared with controls. In summary, RLX has a potent widening effect on the cervix of the common marmoset monkey. Although E2 is not required for this RLX effect, a combined application of E2 and RLX induced the most prominent cervical ripening.


2017 ◽  
Vol 59 (7) ◽  
pp. 807-821 ◽  
Author(s):  
Karla K. Ausderau ◽  
Caitlin Dammann ◽  
Kathy McManus ◽  
Mary Schneider ◽  
Marina E. Emborg ◽  
...  

2013 ◽  
Vol 9 (4) ◽  
pp. 20130409 ◽  
Author(s):  
Sae Gonda ◽  
Shuichi Matsumura ◽  
Shoichiro Saito ◽  
Yasuhiro Go ◽  
Hiroo Imai

The extraoral presence of taste signal transduction proteins has recently been reported in rodents and humans. Here, we report for the first time the presence of these signal transduction proteins in the caecum of a non-human primate, the common marmoset. Quantitative RT-PCR data on the gene expression of taste signal transduction molecules (gustducin and TRPM5) in common marmosets suggested high expression in the caecum, which was not observed in other non-human primates. Immunohistochemical analysis confirmed the specific presence of gustducin and taste receptors in marmoset caecal cells. These results may relate to the specific feeding behaviour of marmosets, which consume plant exudates, primarily gums.


Hippocampus ◽  
2004 ◽  
Vol 14 (5) ◽  
pp. 615-627 ◽  
Author(s):  
Helen H.J. Pothuizen ◽  
Joram Feldon ◽  
Ana L. Jongen-Rêlo

Sign in / Sign up

Export Citation Format

Share Document