scholarly journals Ctenophore immune cells produce chromatin traps in response to pathogens and NADPH-independent stimulus

2020 ◽  
Author(s):  
Lauren E. Vandepas ◽  
Caroline Stefani ◽  
Nikki Traylor-Knowles ◽  
Frederick W. Goetz ◽  
William E. Browne ◽  
...  
Keyword(s):  
Immune Response ◽  
Immune Cells ◽  
Cellular Immune Response ◽  
Cell Types ◽  
Extracellular Dna ◽  
Response Behavior ◽  
First Response ◽  
Stem Lineage ◽  
Cellular Immune ◽  
Extracellular Dna Traps

AbstractThe formation of extracellular DNA traps (ETosis) is a mechanism of first response by specific immune cells following pathogen encounters. Historically a defining behavior of vertebrate neutrophils, cells capable of ETosis were recently discovered in several invertebrate taxa. Using pathogen and drug stimuli, we report that ctenophores – thought to represent the earliest-diverging animal lineage – possess cell types capable of ETosis, suggesting that this cellular immune response behavior likely evolved early in the metazoan stem lineage.

Humoral and cellular immune response to a crude exo-antigen and purified keratinase of Microsporum canis in experimentally infected guinea pigs

1999 ◽  
Vol 37 (2) ◽  
pp. 123-129 ◽  
Author(s):  
B. R. Mignon ◽  
T. Leclipteux ◽  
CH. Focant ◽  
A. J. Nikkels ◽  
G. E. PIErard ◽  
...  
Keyword(s):  
Immune Response ◽  
Cellular Immune Response ◽  
Guinea Pigs ◽  
Microsporum Canis ◽  
Cellular Immune

The humoral and cellular immune response of sheep against Borna disease virus in endemic and non-endemic areas

2004 ◽  
Vol 146 (4) ◽  
pp. 159-172 ◽  
Author(s):  
D. Müller-Doblies ◽  
S. Baumann ◽  
P. Grob ◽  
A. Hülsmeier ◽  
U. Müller-Doblies ◽  
...  
Keyword(s):  
Immune Response ◽  
Disease Virus ◽  
Cellular Immune Response ◽  
Borna Disease Virus ◽  
Endemic Areas ◽  
Cellular Immune ◽  
Borna Disease

Does gamma knife surgery stimulate cellular immune response to metastatic brain tumors? A histopathological and immunohistochemical study

2005 ◽  
Vol 102 (Special_Supplement) ◽  
pp. 180-184 ◽  
Author(s):  
György T. Szeifert ◽  
Isabelle Salmon ◽  
Sandrine Rorive ◽  
Nicolas Massager ◽  
Daniel Devriendt ◽  
...  
Keyword(s):  
Immune Response ◽  
Brain Tumors ◽  
Gamma Knife ◽  
Cellular Immune Response ◽  
Lymphocytic Infiltration ◽  
Gamma Knife Surgery ◽  
Metastatic Brain Tumors ◽  
Content Type ◽  
Cellular Immune ◽  
Fine Print

Object. The aim of this study was to analyze the cellular immune response and histopathological changes in secondary brain tumors after gamma knife surgery (GKS). Methods. Two hundred ten patients with cerebral metastases underwent GKS. Seven patients underwent subsequent craniotomy for tumor removal between 1 and 33 months after GKS. Four of these patients had one tumor, two patients had two tumors, and one patient had three. Histological and immunohistochemical investigations were performed. In addition to routine H & E and Mallory trichrome staining, immunohistochemical reactions were conducted to characterize the phenotypic nature of the cell population contributing to the tissue immune response to neoplastic deposits after radiosurgery. Light microscopy revealed an intensive lymphocytic infiltration in the parenchyma and stroma of tumor samples obtained in patients in whom surgery was performed over 6 months after GKS. Contrary to this, extensive areas of tissue necrosis with either an absent or scanty lymphoid population were observed in the poorly controlled neoplastic specimens obtained in cases in which surgery was undertaken in patients less than 6 months after GKS. Immunohistochemical characterization demonstrated the predominance of CD3-positive T cells in the lymphoid infiltration. Conclusions. Histopathological findings of the present study are consistent with a cellular immune response of natural killer cells against metastatic brain tumors, presumably stimulated by the ionizing energy of focused radiation.

Cellular Immune Response of SIV‐Infected Rhesus Macaques

1990 ◽  
Vol 19 (3-4) ◽  
pp. 177-187
Author(s):  
Thomas P. McGraw ◽  
Benjamin R. Vowels ◽  
M. Eric Gershwin ◽  
Murray B. Gardner
Keyword(s):  
Immune Response ◽  
Cellular Immune Response ◽  
Rhesus Macaques ◽  
Cellular Immune

HIV-infected patients show impaired cellular immune response to influenza vaccination compared to healthy subjects

Vaccine ◽  
2013 ◽  
Vol 31 (28) ◽  
pp. 2914-2918 ◽  
Author(s):  
Massimiliano Fabbiani ◽  
Letizia Sidella ◽  
Maddalena Corbi ◽  
Rosa Martucci ◽  
Michela Sali ◽  
...  
Keyword(s):  
Immune Response ◽  
Influenza Vaccination ◽  
Cellular Immune Response ◽  
Healthy Subjects ◽  
Cellular Immune
Sign in / Sign up

Export Citation Format

Share Document