scholarly journals Genetic determinants of trehalose utilization are not associated with severe Clostridium difficile infection

2019 ◽  
Author(s):  
Katie Saund ◽  
Krishna Rao ◽  
Vincent B. Young ◽  
Evan S. Snitkin

ABSTRACTIn a case-control study of patients with C. difficile infection we found no statistically significant association between the presence of trehalose utilization variants in infecting C. difficile strains and development of severe infection. These results do not support trehalose utilization conferring enhanced virulence in the context of human C. difficile infections.

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Katie Saund ◽  
Krishna Rao ◽  
Vincent B Young ◽  
Evan S Snitkin

Abstract In a case–control study of patients with Clostridium difficile infection, we found no statistically significant association between the presence of trehalose utilization variants in infecting C. difficile strains and development of severe infection outcome. These results do not support trehalose utilization conferring enhanced virulence in the context of human C. difficile infections.


2011 ◽  
Vol 124 (3) ◽  
pp. 276.e1-276.e7 ◽  
Author(s):  
Susanna Naggie ◽  
Becky A. Miller ◽  
Kimberly B. Zuzak ◽  
Brian W. Pence ◽  
Ashley J. Mayo ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Thorsten Fuereder ◽  
Danjel Koni ◽  
Andreas Gleiss ◽  
Michael Kundi ◽  
Athanasios Makristathis ◽  
...  

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