scholarly journals Noise Gated by Dendrosomatic Interactions Increases Information Transmission

2017 ◽  
Author(s):  
Richard Naud ◽  
Alexandre Payeur ◽  
André Longtin

We study how noise in active dendrites affects information transmission. A mismatch of both noise and refractoriness between a dendritic compartment and a somatic compartment is shown to lead to an input-dependent exchange of leadership, where the dendrite entrains the soma for weak stimuli and the soma entrains the dendrite for strong stimuli. Using this simple mechanism, the noise in the dendritic compartment can boost weak signals without affecting the output of the neuron for strong stimuli. We show that these mechanisms give rise to a noise-induced increase of information transmission by neural populations.

2020 ◽  
Author(s):  
Carl van Vreeswijk ◽  
Farzada Farkhooi

Dendrites play an essential role in the integration of highly fluctuating input into neurons across all nervous systems. Nevertheless, they are often studied under the conditions where inputs to dendrites are sparse. Up to date, the dynamic properties of active dendrites facing in-vivo-like fluctuating input remains elusive. In this paper, we uncover fundamentally new dynamics in a canonical model of a dendritic compartment with active calcium channels, receiving in-vivo-like fluctuating input. We show in-vivo-like noise induces non-monotonic or bistable dynamics in the input-output relation of a dendritic compartment, both of which are absent in a noiseless condition. Our analysis shows that the timescales of the activation gating variable of the dendritic calcium dynamics determine noise-induced spontaneous order in the system. Noise can induce non-monotonicity or bistability with fast or slow calcium activation respectively. We characterize these noise-induced phenomena and their influence on the input-output relation. Furthermore, we show that timescales of the emerging stochastic bistable dynamics go far beyond a deterministic system due to stochastic switching between the solutions. Our results reveal that noise contributes to sustained dendritic nonlinearities, and it could be considered a principal component of the dendritic input integration strategies.


Author(s):  
C J R Sheppard

The confocal microscope is now widely used in both biomedical and industrial applications for imaging, in three dimensions, objects with appreciable depth. There are now a range of different microscopes on the market, which have adopted a variety of different designs. The aim of this paper is to explore the effects on imaging performance of design parameters including the method of scanning, the type of detector, and the size and shape of the confocal aperture.It is becoming apparent that there is no such thing as an ideal confocal microscope: all systems have limitations and the best compromise depends on what the microscope is used for and how it is used. The most important compromise at present is between image quality and speed of scanning, which is particularly apparent when imaging with very weak signals. If great speed is not of importance, then the fundamental limitation for fluorescence imaging is the detection of sufficient numbers of photons before the fluorochrome bleaches.


1964 ◽  
Author(s):  
Edwin C. Carterette ◽  
Morton P. Friedman ◽  
Robert Cosmujes

2019 ◽  
pp. 52-56
Author(s):  
V. V. Tarapata

The article describes the prerequisites for the use of educational robotics in the school course of informatics, the history of the development of its directions and the normative basis for its use in modern school education. A typical model of an educational robotic project for the organization of research and project activities of students has been proposed. The technological chart of the lesson as an example of the implementation of a robotic project in the framework of the research activities on informatics is considered. Approaches to the organization of educational activities, teaching tools and ways of evaluation in informatics class on the theme “Information processes. Information transmission” when using the project approach are described.


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