scholarly journals Resting heart rate rapid reduction by moderate exercise evolutionarily encoded

2017 ◽  
Author(s):  
Gábor Pavlik ◽  
Eva Bakács ◽  
Eszter Csajági ◽  
Tibor Bakács ◽  
Judit Noe ◽  
...  

AbstractBackgroundGlobal physical inactivity pandemic is responsible for more than 5 million deaths annually through its effects on non-communicable diseases. This requires urgent intervention.ObjectiveTo investigate associations of physical activity with cardiovascular fitness in a cross-sectional retrospective observational study. Data were collected for 21 years from 2530 healthy volunteers and athletes representing the entire spectrum of physical activity from the totally inactive sedentary persons to the highly trained national athletes.MethodsSimple echocardiographic parameters of cardiovascular fitness were analyzed. Cardiac fitness was characterized by reduced resting heart rate, increased relative left ventricular muscular mass, improved left ventricular diastolic function and peak exercise oxygen consumption.ResultsWe found that even moderate exercise is associated with improved cardiac fitness. The largest improvement of fitness was observed between the inactive and the least active group, whereas fitness decreased in the highly trained national athletes enduring up to 20 training hours per week.ConclusionsOur finding that moderate exercise is associated with positive changes in sedentary persons makes sense only in the light of evolution. Human endurance running performance capabilities that emerged ~2 million years ago are evolutionary coded and seems to be awakened even by moderate exercise. This finding would help physicians to encourage patients for doable and sustainable behavioral change who are currently inactive and find physical exercise intimidating. (Word count: 218)AbbreviationsCV(cardiovascular)CVD(cardiovascular disease)CVH(cardiovascular health)HD(heart disease)BSA(body surface area)LV(left ventricular)RHR(Resting Heart Rate)Key PointsThis cross-sectional retrospective observational echocardiographic study of 2530 healthy volunteers and athletes representing the entire spectrum of physical activity from the totally inactive sedentary persons to the highly trained national athletes found that it is possible to experience cardiovascular benefits soon after the sedentary persons become physically active. This makes sense only in the light of evolution. With increasing performance level cardiovascular fitness is increased up to a point but then decreased in highly trained national athletes.The non-invasive and simple echocardiographic test could be used to monitor exercise induced positive changes. This would help physicians in their efforts to promote the expansive benefits of exercise in all spectrums of society and encourage patients for doable and sustainable behavioral change.

Author(s):  
Giselle Sarganas ◽  
Anja Schienkiewitz ◽  
Jonas D. Finger ◽  
Hannelore K. Neuhauser

AbstractTo track blood pressure (BP) and resting heart rate (RHR) in children and adolescents is important due to its associations with cardiovascular outcomes in the adulthood. Therefore, the aim of this study was to examine BP and RHR over a decade among children and adolescents living in Germany using national examination data. Cross-sectional data from 3- to 17-year-old national survey participants (KiGGS 2003–06, n = 14,701; KiGGS 2014–17, n = 3509) including standardized oscillometric BP and RHR were used for age- and sex-standardized analysis. Measurement protocols were identical with the exception of the cuff selection rule, which was accounted for in the analyses. Different BP and RHR trends were observed according to age-groups. In 3- to 6-year-olds adjusted mean SBP and DBP were significantly higher in 2014–2017 compared to 2003–2006 (+2.4 and +1.9 mm Hg, respectively), while RHR was statistically significantly lower by −3.8 bpm. No significant changes in BP or in RHR were observed in 7- to 10-year-olds over time. In 11- to 13-year-olds as well as in 14- to 17-year-olds lower BP has been observed (SBP −2.4 and −3.2 mm Hg, respectively, and DBP −1.8 and −1.7 mm Hg), while RHR was significantly higher (+2.7 and +3.7 bpm). BP trends did not parallel RHR trends. The downward BP trend in adolescents seemed to follow decreasing adult BP trends in middle and high-income countries. The increase in BP in younger children needs confirmation from other studies as well as further investigation. In school-aged children and adolescents, the increased RHR trend may indicate decreased physical fitness.


2021 ◽  
Vol 35 ◽  
pp. 100830
Author(s):  
Julius C. Heemelaar ◽  
Augustinus D.G. Krol ◽  
Marloes Louwerens ◽  
Saskia L.M.A. Beeres ◽  
Eduard R. Holman ◽  
...  

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Yuksel Cavusoglu ◽  
Omer Kozan ◽  
Ahmet Temizhan ◽  
Serdar Kucukoglu

Purpose: Resting heart rate (HR), health related quality of life (HQoL) and NYHA functional capacity are referred as important determinants of prognosis and targets of therapy in heart failure (HF). REALITY HF (Resting Heart Rate and Real Life Treatment Modality in Outpatients with Left Ventricular Systolic Dysfunction) study data were analyzed for the evaluation of any relationship of resting HR with HQoL assessed by Kansas City Cardiomyopathy Questionnaire (KCCQ) and NYHA functional class. Methods: REALITY HF was a multicenter, prospective registry designed to evaluate HF patients’ characteristics and effects of treatment modalities on resting HR and enrolled 1057 patients (age 61±12 years) with LVEF <40%. 781 (74%) patients in sinus rhythm were included in this analysis. Patients were classified into 4 groups according to the quartiles of HR: Q1:<68 bpm (n=234), Q2:69-75 bpm (n=189), Q3:76-87 bpm (n=194) and Q4:>87 bpm (n=164). KCCQ was completed in a random sample of 320 (Q1:n=27, Q2:n=99, Q3:n=125, Q4:n=69) patients, in which higher scores show better patient’s health status. Results: During enrollment, 82% of patients were receiving ≥2 drugs including ACE[[Unable to Display Character: &#304;]]/ARB, beta blocker, aldosterone blocker, diuretic or digoxin. Resting HR was 76±14 bpm and 68% of patients had a resting HR ≥70 bpm. KCCQ overall summary score (OSC) was found to be 75.7±13.2 in those in Q1, 65.5±20.8 in Q2, 64.4±20.6 in Q3 and 58.3±21.2 in Q4 (p=0.004) and KCCQ clinical summary score (CSS) was 80.4±15.7 in those in Q1, 70.0±22.4 in Q2, 69.9±21.9 in Q3 and 63.8±23.3 in Q4 (p=0.016). Also, there was a significant negative correlation between resting HR and OSC (p=0.008) or CSS (p=0.031). The distribution of NYHA-I patients for Q1, Q2, Q3 and Q4 were 40.7%, 22.8%, 23.8% and 12.7%, NYHA-II patients-30.8%, 23.1%, 27.2% and 18.9%, NYHA-III patients-21.2%, 23.9%, 24.3% and 30.6% and NYHA-IV patients-22.7%, 34.1%, 22.7% and 20.5%, respectively (p<0.001). Also, resting HR were found to gradually and significantly increase across NYHA categories (72.8±12 bpm in NYHA-I, 76.1±13 bpm in NYHA-II, 80.2±15 bpm in NYHA-III and 78.9±16 bpm in NYHA-IV, p<0.001). Conclusions: These results suggest that elevated resting HR in HF patients is associated with impaired HQoL and worse NYHA functional capacity.


Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Ramtin Anousheh ◽  
David E Krummen ◽  
Navinder S Sawhney ◽  
Wei Chung Chen ◽  
Linda Tone ◽  
...  

To investigate the association between resting heart rate (HR) and defibrillation threshold (DFT) in patients (pts) undergoing ICD implantation. DFT testing is usually considered standard of care during ICD implantation. However, the risk factors for high DFTs remain ill defined and the extent of testing required at implant has not been well defined. Baseline HR has been associated with higher DFTs in prior studies. We studied 128 pts undergoing ICD implantation. Baseline HR and DFTs were determined. HR was determined using ECGs obtained in the resting position on the day of ICD implantation. DFT testing was done during ICD implantation. We excluded 13 pts who were on amiodarone. The baseline characteristics of pts in the study are shown below in the table below (values in parenthesis represents standard error of the mean): First, a multivariate analysis of the association between baseline HR and DFT was performed, adjusting for left ventricular ejection fraction (LVEF), gender, body surface area (BSA) and beta blocker therapy. For every 10 beat increase in heart rate, DFT increased by 1 joule (p=0.02). Gender and beta blocker therapy did not effect this association. Second, pts were dichotomized based on DFTs to low (<15 joules) and high (≥15 joules). Mean resting HR was significantly higher among pts with high DFT (79 bpm) compared to those with low DFT (70 bpm) after adjusting for LVEF and BSA (p=0.01). Baseline resting HR is a risk factor for high DFT and may help define a higher risk pt population undergoing DFT testing.


Author(s):  
Kyle R Sochacki ◽  
David Dong ◽  
Leif Peterson ◽  
Patrick C McCulloch ◽  
Kevin Lisman ◽  
...  

ObjectivesThe purpose of this study was to determine orthopaedic surgery residents’ and attending surgeons’ resting heart rate (RHR) and heart rate variability (HRV) and if there is a correlation between subject-specific variables (age, attending surgeon, resident, postgraduate year (PGY) level, gender, number of calls, total hours worked, and total hours of sleep) and surgeon RHR and HRV.MethodsOrthopaedic surgery residents and attending surgeons at a single institution were prospectively enrolled and provided a validated wearable device to determine hours of sleep, RHR and HRV. Demographic information, hours worked and overnight calls were recorded. Bivariate correlations were determined using the Spearman rank correlation. Multiple linear regression models were constructed to determine the effect of relevant variables. All p values were reported, and a significance level of α=0.05 was used (p<0.05).ResultsTwenty-one of 26 enrolled subjects completed the 4-week study. The average RHR and HRV for orthopaedic surgeons was 61.8+10.0 bpm and 42.96+21.2ms, respectively. Residents had a significantly higher RHR (66.4+8.4 vs 55.6+8.9, p=0.011) compared with attending surgeons. Overnight calls had the strongest association with decreased HRV (r=−0.447; p=0.038), moderate positive correlation with RHR (r=0.593; p=0.005) and weak negative correlation with HRV (r=−0.469; p=0.032). There was no significant correlation between PGY level, gender, total hours worked and total hours of sleep with RHR or HRV.ConclusionOrthopaedic surgeons have poor RHR and HRV. Additionally, the number of overnight calls had the strongest correlation with worse RHR and HRV.Level of evidenceLevel II; diagnostic, individual cross-sectional study with a consistently applied reference standard.


Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 310
Author(s):  
Kevin J. Scully ◽  
Laura T. Jay ◽  
Steven Freedman ◽  
Gregory S. Sawicki ◽  
Ahmet Uluer ◽  
...  

Measures of body fat and lean mass may better predict important clinical outcomes in patients with cystic fibrosis (CF) than body mass index (BMI). Little is known about how diet quality and exercise may impact body composition in these patients. Dual X-ray absorptiometry (DXA) body composition, 24-h dietary recall, and physical activity were assessed in a cross-sectional analysis of 38 adolescents and adults with CF and 19 age-, race-, and gender-matched healthy volunteers. Compared with the healthy volunteers, participants with CF had a lower appendicular lean mass index (ALMI), despite no observed difference in BMI, and their diets consisted of higher glycemic index foods with a greater proportion of calories from fat and a lower proportion of calories from protein. In participants with CF, pulmonary function positively correlated with measures of lean mass, particularly ALMI, and negatively correlated with multiple measures of body fat after controlling for age, gender, and BMI. Higher physical activity levels were associated with greater ALMI and lower body fat. In conclusion, body composition measures, particularly ALMI, may better predict key clinical outcomes in individuals with CF than BMI. Future longitudinal studies analyzing the effect of dietary intake and exercise on body composition and CF-specific clinical outcomes are needed.


2021 ◽  
pp. 1-20
Author(s):  
Yume Imahori ◽  
Davide L. Vetrano ◽  
Petter Ljungman ◽  
Chengxuan Qiu

Background: Markers of altered cardiac function might predict cognitive decline and dementia. Objective: This systematic review aims to review the literature that examines the associations of various electrocardiogram (ECG) markers with cognitive decline and dementia in middle-aged and elderly populations. Methods: We searched PubMed, Embase, and Web of Science through 1 July 2020 for literature and conducted a systematic literature review. We included studies examining the associations of ECG markers (e.g., left ventricular hypertrophy [LVH], spatial QRS-T angle, and QT prolongation) with cognitive function and dementia in adult populations regardless of study setting and design, but excluded studies examining atrial fibrillation and heart rate variability. Results: Fourteen community-based cross-sectional and longitudinal studies were identified. ECG markers were investigated in association with dementia in four prospective studies, and with cognitive decline in ten prospective studies. ECG-assessed LVH was associated with dementia in one study while five heterogeneous prospective studies yielded inconsistent associations with cognitive decline. Regarding ventricular repolarization markers, spatial QRS-T angle was associated with cognitive decline in one study while another study found no association between QT prolongation and cognitive decline. High resting heart rate was associated with both dementia and cognitive decline in one study but not associated with dementia in another study. P-wave abnormality was significantly associated with incident dementia and cognitive decline in one prospective study. Conclusion: Some ECG markers were associated with incident dementia and cognitive decline. However, limited number of heterogeneous studies did not allow us to make firm conclusions. Further studies are needed.


2020 ◽  
Vol 44 (2) ◽  
pp. 149-157
Author(s):  
Duke D. Biber ◽  
Chrissy Knoll

The primary objective was to (a) test the effectiveness of an Exercise Is Medicine® on Campus (EIM-OC) program in a university setting and (b) compare the baseline levels of physical activity, mental health, and physical health with post-EIM-OC levels. Referred and consenting students ( n = 9) participated in a 12-week program. At pre- and postprogram, participants completed measures of current health behaviors, obstacles to physical activity, health goals, physical activity history, biometric screening (resting heart rate, blood pressure (BP), waist-to-hip ratio, body composition percentage via bioelectrical impedance, cardiovascular and muscular endurance baseline, and flexibility), perceived stress, and self-compassion. All of the participants adhered to 100% of the program. Participants experienced a decrease in resting heart rate, body composition, and BP and an increase in sleep, physical activity, and self-compassion. The program will be implemented with a larger sample of referred students with the goal of reducing risk or prevalence of chronic disease.


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