scholarly journals Listening to speech induces coupling between auditory and motor cortices in an unexpectedly rate-restricted manner

2017 ◽  
Author(s):  
M. Florencia Assaneo ◽  
David Poeppel
Keyword(s):  
Perception And Action ◽  
Fundamental Parameter ◽  
Sensorimotor Processing ◽  
Neural Architecture ◽  
A Value ◽  
The Mean ◽  
Underlying Mechanisms ◽  
Measure Synchronization ◽  
Speech Motor ◽  
Motor Interaction

The relation between perception and action remains a fundamental question for neuroscience. In the context of speech, existing data suggest an interaction between auditory and speech-motor cortices, but the underlying mechanisms remain incompletely characterized. We fill a basic gap in our understanding of the sensorimotor processing of speech by examining the synchronization between auditory and speech-motor regions over different speech rates, a fundamental parameter delimiting successful perception. First, using MEG we measure synchronization between auditory and speech-motor regions while participants listen to syllables at various rates. We show, surprisingly, that auditory-motor synchrony is significant only over a restricted range and is enhanced at ~4.5 Hz, a value compatible with the mean syllable rate across languages. Second, neural modeling reveals that this modulated coupling plausibly emerges as a consequence of the underlying neural architecture. The findings suggest that the auditory-motor interaction should be interpreted rather conservatively when considering phase space.

THE EFFECT OF ALTERATION OF THYROXINE BINDING CAPACITY ON THE DIALYZABLE AND ABSOLUTE FRACTIONS OF TRIIODOTHYRONINE IN CIRCULATION

1973 ◽  
Vol 72 (2) ◽  
pp. 265-271 ◽  
Author(s):  
J. H. Dussault ◽  
D. A. Fisher ◽  
J. T. Nicoloff ◽  
V. V. Row ◽  
R. Volpe
Keyword(s):  
Correlation Coefficient ◽  
Inverse Relationship ◽  
Binding Capacity ◽  
Hormone Concentration ◽  
Thyroxine Binding Globulin ◽  
Serum Thyroxine ◽  
A Value ◽  
The Mean ◽  
Male Subjects ◽  
Female Subjects

ABSTRACT In order to determine the effect of alterations in binding capacity of thyroxine binding globulin (TBG) on triiodothyronine (T3) metabolism, studies were conducted in 10 patients with idiopathically low (7 subjects) or elevated (3 subjects) TBG levels and 10 subjects given norethandrolone (7 male subjects) or oestrogen (3 female subjects). Measurements of serum thyroxine (T4) concentration, maximal T4 binding capacity, serum T3 concentration and per cent dialyzable T3 were conducted. Serum T3 was measured both by chemical and radioimmunoassay methods. In patients with idiopathically low TBG, the mean serum T4 concentration was low (2.4 μg/100 ml), the mean serum T3 level low (55 ng/100 ml), the mean per cent dialyzable T3 increased (0.52%), and the calculated free T3 concentration normal (186 pg/100 ml). In patients with idiopathically high TBG levels the mean T4 concentration was high (10.3 μg/100 ml), the mean T3 level slightly elevated (127 ng/100 ml), the% dialyzable T3 low (0.10%) and the calculated free T3 concentration low normal (123 pg/100 ml). The correlation coefficient between the per cent dialyzable T3 and maximal TBG binding capacity in the 20 subjects was 0.68, a value significant at the P < 0.01 level. Thus, alterations in binding capacity of TBG seem to influence T3 and T4 metabolism similarly; the inverse relationship between the % of dialyzable hormone and total hormone concentration tends to keep the absolue levels of free hormones stable.

PENGARUH PENDIDIKAN KESEHATAN REPRODUKSI PADA PEER GROUP (TEMAN SEBAYA) TERHADAP PENGETAHUAN DAN PERSEPSI REMAJA TENTANG PENDEWASAAN USIA PERKAWINAN DI SMA NEGERI 1 KECAMATAN NAMORAMBE KAB. DELI SERDANG 2018

2020 ◽  
Vol 1 (2) ◽  
pp. 56-66
Author(s):  
Irma Linda
Keyword(s):  
Standard Deviation ◽  
Health Education ◽  
Reproductive Health ◽  
Peer Group ◽  
Peer Groups ◽  
A Value ◽  
Significant Difference ◽  
Reproductive Health Education ◽  
The Mean ◽  
Adolescent Perceptions

Background: Early marriages are at high risk of marital failure, poor family quality, young pregnancies at risk of maternal death, and the risk of being mentally ill to foster marriage and be responsible parents. Objective: To determine the effect of reproductive health education on peer groups (peers) on the knowledge and perceptions of adolescents about marriage age maturity. Method: This research uses the Quasi experimental method with One group pre and post test design, conducted from May to September 2018. The statistical analysis used in this study is a paired T test with a confidence level of 95% (α = 0, 05). Results: There is an average difference in the mean value of adolescent knowledge between the first and second measurements is 0.50 with a standard deviation of 1.922. The mean difference in mean scores of adolescent perceptions between the first and second measurements was 4.42 with a standard deviation of 9.611. Conclusion: There is a significant difference between adolescent knowledge on the pretest and posttest measurements with a value of P = 0.002, and there is a significant difference between adolescent perceptions on the pretest and posttest measurements with a value of p = 0.001. Increasing the number of facilities and facilities related to reproductive health education by peer groups (peers) in adolescents is carried out on an ongoing basis at school, in collaboration with local health workers as prevention of risky pregnancy.

The evolution of star formation in QSOs according to WISE

2020 ◽  
Vol 15 (S359) ◽  
pp. 33-34
Author(s):  
K. A. Cutiva-Alvarez ◽  
R. Coziol ◽  
J. P. Torres-Papaqui ◽  
H. Andernach ◽  
A. C. Robleto-Orús
Keyword(s):  
Star Formation ◽  
Gradual Increase ◽  
A Value ◽  
Star Formation Activity ◽  
The Mean ◽  
Lower Redshift

AbstractUsing WISE data, we calibrated the W2-W3 colors in terms of star formation rates (SFRs) and applied this calibration to a sample of 1285 QSOs with the highest flux quality, covering a range in redshift from z ˜ 0.3 to z ˜ 3.8. According to our calibration, the SFR increases continuously, reaching a value at z ˜ 3.8 about 3 times higher on average than at lower redshift. This increase in SFR is accompanied by an increase of the BH mass by a factor 100 and a gradual increase of the mean Eddington ratio from 0.1 to 0.3 up to z ˜ 1.5 – 2.0, above which the ratio stays constant, despite a significant increase in BH mass. Therefore, QSOs at high redshifts have both more active BHs and higher levels of star formation activity.

scholarly journals Demyelination and remyelination detected in an alternative cuprizone mouse model of multiple sclerosis with 7.0 T multiparameter magnetic resonance imaging

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shuang Ding ◽  
Yu Guo ◽  
Xiaoya Chen ◽  
Silin Du ◽  
Yongliang Han ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Mouse Model ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Blue Staining ◽  
Resonance Imaging ◽  
The Mean ◽  
Underlying Mechanisms

AbstractThe aim of this study was to investigate the mechanisms underlying demyelination and remyelination with 7.0 T multiparameter magnetic resonance imaging (MRI) in an alternative cuprizone (CPZ) mouse model of multiple sclerosis (MS). Sixty mice were divided into six groups (n = 10, each), and these groups were imaged with 7.0 T multiparameter MRI and treated with an alternative CPZ administration schedule. T2-weighted imaging (T2WI), susceptibility-weighted imaging (SWI), and diffusion tensor imaging (DTI) were used to compare the splenium of the corpus callosum (sCC) among the groups. Prussian blue and Luxol fast blue staining were performed to assess pathology. The correlations of the mean grayscale value (mGSV) of the pathology results and the MRI metrics were analyzed to evaluate the multiparameter MRI results. One-way ANOVA and post hoc comparison showed that the normalized T2WI (T2-nor), fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD) values were significantly different among the six groups, while the mean phase (Φ) value of SWI was not significantly different among the groups. Correlation analysis showed that the correlation between the T2-nor and mGSV was higher than that among the other values. The correlations among the FA, RD, MD, and mGSV remained instructive. In conclusion, ultrahigh-field multiparameter MRI can reflect the pathological changes associated with and the underlying mechanisms of demyelination and remyelination in MS after the successful establishment of an acute CPZ-induced model.

scholarly journals The fate of Si and Fe while nuclear glass alters with steel and clay

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
C. Carriere ◽  
P. Dillmann ◽  
S. Gin ◽  
D. Neff ◽  
L. Gentaz ◽  
...  
Keyword(s):  
Dissolution Rate ◽  
Protective Layer ◽  
Glass Dissolution ◽  
A Value ◽  
Waste Forms ◽  
Controlling Mechanism ◽  
Geological Repository ◽  
The Mean ◽  
High Level ◽  
Initial Dissolution Rate

AbstractThe French concept developed to dispose high-level radioactive waste in geological repository relies on glassy waste forms, isolated from the claystone host rock by steel containers. Understanding interactions between glass and surrounding materials is key for assessing the performance of a such system. Here, isotopically tagged SON68 glass, steel and claystone were studied through an integrated mockup conducted at 50 °C for 2.5 years. Post-mortem analyses were performed from nanometric to millimetric scales using TEM, STXM, ToF-SIMS and SEM techniques. The glass alteration layer consisted of a crystallized Fe-rich smectite mineral, close to nontronite, supporting a dissolution/reprecipitation controlling mechanism for glass alteration. The mean glass dissolution rate ranged between 1.6 × 10−2 g m−2 d−1 to 3.0 × 10−2 g m−2 d−1, a value only 3–5 times lower than the initial dissolution rate. Thermodynamic calculations highlighted a competition between nontronite and protective gel, explaining why in the present conditions the formation of a protective layer is prevented.

scholarly journals Snow density along the route traversed by the Japanese-Swedish Antarctic Expedition 2007/08

2012 ◽  
Vol 58 (209) ◽  
pp. 529-539 ◽  
Author(s):  
Shin Sugiyama ◽  
Hiroyuki Enomoto ◽  
Shuji Fujita ◽  
Kotaro Fukui ◽  
Fumio Nakazawa ◽  
...  
Keyword(s):  
Wind Speed ◽  
Surface Wind ◽  
Coastal Region ◽  
Snow Density ◽  
Syowa Station ◽  
Near Surface ◽  
A Value ◽  
Surface Snow ◽  
The Mean ◽  
The Antarctic

AbstractDuring the Japanese-Swedish Antarctic traverse expedition of 2007/08, we measured the surface snow density at 46 locations along the 2800 km long route from Syowa station to Wasa station in East Antarctica. The mean snow density for the upper 1 (or 0.5) m layer varied from 333 to 439 kg m-3 over a region spanning an elevation range of 365-3800 ma.s.l. The density variations were associated with the elevation of the sampling sites; the density decreased as the elevation increased, moving from the coastal region inland. However, the density was relatively insensitive to the change in elevation along the ridge on the Antarctic plateau between Dome F and Kohnen stations. Because surface wind is weak in this region, irrespective of elevation, the wind speed was suggested to play a key role in the near-surface densification. The results of multiple regression performed on the density using meteorological variables were significantly improved by the inclusion of wind speed as a predictor. The regression analysis yielded a linear dependence between the density and the wind speed, with a coefficient of 13.5 kg m-3 (m s-1)-1. This relationship is nearly three times stronger than a value previously computed from a dataset available in Antarctica. Our data indicate that the wind speed is more important to estimates of the surface snow density in Antarctica than has been previously assumed.

Normal levels of vitamin A in tissues of the Syrian hamster (Mesocricetus auratus) determined colorimetrically

1988 ◽  
Vol 22 (2) ◽  
pp. 117-121 ◽  
Author(s):  
M. E. Robinson ◽  
A. M. Verrinder Gibbins ◽  
M. H. Hardy
Keyword(s):  
Vitamin A ◽  
Syrian Hamster ◽  
Cheek Pouch ◽  
Standard Diet ◽  
Male And Female ◽  
Mean Values ◽  
A Value ◽  
Significant Difference ◽  
Wet Weight ◽  
The Mean

Vitamin A levels in tissues of 20 normal adult hamsters on a standard diet were measured colorimetrically. No significant difference between male and female animals was found for any of the tissues sampled. The mean vitamin A value for blood plasma in 20 animals was 53·4 μg/dl. Mean values for liver, kidneys, flank skin and cheek pouch were 813, 1·29, 1·84 and 1·31 mg/g wet weight, respectively. The vitamin assay was less suitable for small organs such as trachea.

scholarly journals Predictive value of resistive index in graft survival after kidney transplant

2014 ◽  
Vol 86 (4) ◽  
pp. 325 ◽  
Author(s):  
Saverio Forte ◽  
Pasquale Martino ◽  
Silvano Palazzo ◽  
Matteo Matera ◽  
Floriana Giangrande ◽  
...  
Keyword(s):  
Graft Survival ◽  
Predictive Value ◽  
Roc Analysis ◽  
Resistance Index ◽  
Resistive Index ◽  
A Value ◽  
Calculated Parameter ◽  
The Status ◽  
The Mean

Introduction: The intrarenal resistance index (RI) is a calculated parameter for the assessment of the status of the graft during the follow-up ultrasound of the transplanted kidney. Currently it is still unclear the predictive value of RI, also in function of the time. Materials and Methods: We retrospectively investigated the correlation between the RI and the graft survival (GS) and the overall survival (OS) after transplantation. We evaluated 268 patients transplanted between 2003 and 2011, the mean followup was 73 months (12-136). The RI was evaluated at 8 days, 6 months, 1 year and 3 years. The ROC analysis was used to calculate the predictive value of RI and the Kaplan Mayer curves was used to evaluated the OS and PS. Results: The ROC analysis, correlated to the GS, identified a value of RI equal to 0.75 as a cut-off. All patients was stratified according to the RI at 8 days (RI ≤ 0,75: 212 vs RI &gt; 0.75: 56), at 6 months (RI ≤ 0.75: 237 vs RI &gt; 0.75: 31), at 1 year (RI ≤ 0.75: 229 vs RI &gt; 0.75: 39) and at 3 years (RI ≤ 0.75: 224 vs RI &gt; 0.75: 44). The RI showed statistically significant differences between the two groups in favor of those who had an RI ≤ 0.75 only at 8 days and at 6 moths (p = 0.0078 and p = 0.02 to 8 days to 6 months) on the GS. On the contrary, we observed that the RI estimated at 1 year and 3 years has not correlated with the GS. The same RI cut-off was correlate with PS after transplantation. We observed that there are no correlations between the RI and OS. Conclusions: The RI proved to be a good prognostic factor on survival organ when it was evaluated in the first months of follow- up after transplantation. This parameter does not appear, however, correlate with OS of the transplanted subject.

The roles of acidosis and lactate in the behavioral hypothermia of exhausted lizards

1999 ◽  
Vol 202 (3) ◽  
pp. 325-331
Author(s):  
E.L. Wagner ◽  
D.A. Scholnick ◽  
T.T. Gleeson
Keyword(s):  
Blood Lactate ◽  
Thermal Gradient ◽  
Elevated Blood ◽  
Body Temperatures ◽  
Exhausting Exercise ◽  
A Value ◽  
Arterial Ph ◽  
Injection Control ◽  
The Mean ◽  
Lactate Levels

We conducted this study to determine whether two of the physiological changes associated with non-sustainable exercise, elevated blood lactate levels and decreased arterial pH, contribute to the behavioral hypothermia exhibited by exhausted lizards. Dipsosaurus dorsalis were placed in a thermal gradient and their body temperatures were recorded from 08:00 to 14:00 h. At 14:00 h, animals were subjected to different experimental regimens. In the exercise (E) regimen, animals at 40 degrees C were forced to exercise maximally for 5 min on a treadmill. In the lactate (L) regimen, animals were infused with 11.5 ml kg-1 of 250–500 mmol l-1 sodium lactate. In the osmolarity control (O) regimen, animals were injected with 11.5 ml kg-1 of 500 mmol l-1 NaCl, and in the injection control (I) regimen, animals were injected with 11.5 ml kg-1 of 150 mmol l-1 NaCl. In the hypercapnia (H) regimen, the thermal gradient was flushed with a gas mixture containing 10 % CO2, 21 % O2 and 69 % N2, a treatment that lowers the arterial pH of D. dorsalis to a value comparable with that imposed by exhaustive exercise. A group of control (C) animals was left undisturbed in the thermal gradient for 24 h. Animals in all experimental groups were returned to the thermal gradient, and their cloacal temperatures were monitored until 08:00 h the following morning. The mean cloacal temperature of E animals underwent a significant decrease of 4–7 degrees C, relative to control animals, which persisted for 7 h. The mean cloacal temperatures of animals subjected to 2 h of regimen H also decreased by 3.5-9 degrees C and remained depressed for 12 h following the beginning of the treatment. L, O and I animals did not undergo a significant change in body temperature following treatment, and their mean body temperatures did not differ from those of C animals at any time during the experiment. The results of this study suggest that the metabolic acidosis, but not the elevated blood lactate level, that follows exhausting exercise might play a role in the behavioral hypothermia that follows exhausting exercise in D. dorsalis.

scholarly journals The Relationship Between Digital Egg Coloration and Egg Survival in Landlocked Fall Chinook

2018 ◽  
Vol 7 (1) ◽  
pp. 31
Author(s):  
Holiday Robley ◽  
Michael E. Barnes
Keyword(s):  
South Dakota ◽  
Chinook Salmon ◽  
Color Index ◽  
Oncorhynchus Tshawytscha ◽  
Egg Survival ◽  
A Value ◽  
The Mean ◽  
The Relationship ◽  
Egg Coloration

Digital color values were collected from the eggs of 128 spawns from individual landlocked fall Chinook salmon Oncorhynchus tshawytscha females from Lake Oahe, South Dakota, USA, in 2008, 2009, 2015 and 2016. For all spawns, the mean (SE) a* value, a measure of red-green chromaticness, was 10.99 (0.27), and ranged from 3.98 to 18.71. Mean (SE) b* (yellow-green) was 20.27 (0.32), and ranged from 9.28 to 28.50. Mean (SE) L* (white-black) was 20.73 (0.48), and ranged from 3.98 to 18.71. Egg total color index also showed considerable variation, with a mean (SE) of 23.05 (0.37) and range from 11.70 to 31.64. Egg survival to the eyed-stage was weakly, but significantly, correlated to b* (r = 0.206), L* (r = 0.185), Chroma (r = 0.211), and Entire Color Index (r = 0.211). Spawns with no egg survival had eggs with significantly lower a* values compared to spawns where at least some of the eggs survived to the eyed stage. L*, a*, b*, Chroma, and Entire Color Index varied significantly among the years, but Hue and egg survival to the eyed stage did not. The results of this study indicate a possible link between egg color and landlocked fall Chinook salmon egg survival, possibly due to differences in the diets of feral broodstock females or their ability to deposit bodily carotenoids in the developing eggs.

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