scholarly journals Automating Morphological Profiling with Generic Deep Convolutional Networks

2016 ◽  
Author(s):  
Nick Pawlowski ◽  
Juan C Caicedo ◽  
Shantanu Singh ◽  
Anne E Carpenter ◽  
Amos Storkey

AbstractMorphological profiling aims to create signatures of genes, chemicals and diseases from microscopy images. Current approaches use classical computer vision-based segmentation and feature extraction. Deep learning models achieve state-of-the-art performance in many computer vision tasks such as classification and segmentation. We propose to transfer activation features of generic deep convolutional networks to extract features for morphological profiling. Our approach surpasses currently used methods in terms of accuracy and processing speed. Furthermore, it enables fully automated processing of microscopy images without need for single cell identification.

2021 ◽  
Author(s):  
Daniel Padilla ◽  
Hatem A. Rashwan ◽  
Domènec Savi Puig

Deep learning (DL) networks have proven to be crucial in commercial solutions with computer vision challenges due to their abilities to extract high-level abstractions of the image data and their capabilities of being easily adapted to many applications. As a result, DL methodologies had become a de facto standard for computer vision problems yielding many new kinds of research, approaches and applications. Recently, the commercial sector is also driving to use of embedded systems to be able to execute DL models, which has caused an important change on the DL panorama and the embedded systems themselves. Consequently, in this paper, we attempt to study the state of the art of embedded systems, such as GPUs, FPGAs and Mobile SoCs, that are able to use DL techniques, to modernize the stakeholders with the new systems available in the market. Besides, we aim at helping them to determine which of these systems can be beneficial and suitable for their applications in terms of upgradeability, price, deployment and performance.


2021 ◽  
Vol 11 (3) ◽  
pp. 846-855
Author(s):  
Hamza Riaz ◽  
Jisu Park ◽  
Peter H. Kim ◽  
Jungsuk Kim

The retina is an important organ of the human body, with a crucial function in the vision mechanism. A minor disturbance in the retina can cause various abnormalities in the eye, as well as complex retinal diseases such as diabetic retinopathy. To diagnose such diseases in early stages, many researchers are incorporating machine learning (ML) technique. The combination of medical science with ML improves the healthcare diagnosis systems of hospitals, clinics, and other providers. Recently, AI-based healthcare diagnosis systems assist clinicians in handling more patients in less time and improves diagnosis accuracy. In this paper, we review cutting-edge AI-based retinal diagnosis technologies. This article also briefly describes the potential of the latest densely connected convolutional networks (DenseNets) to improve the performance of diagnosis systems. Moreover, this paper focuses on state-of-the-art results from comprehensive investigations in retinal diagnosis and the development of AI-based retinal healthcare diagnosis approaches with deep-learning models.


2020 ◽  
Author(s):  
Dean Sumner ◽  
Jiazhen He ◽  
Amol Thakkar ◽  
Ola Engkvist ◽  
Esben Jannik Bjerrum

<p>SMILES randomization, a form of data augmentation, has previously been shown to increase the performance of deep learning models compared to non-augmented baselines. Here, we propose a novel data augmentation method we call “Levenshtein augmentation” which considers local SMILES sub-sequence similarity between reactants and their respective products when creating training pairs. The performance of Levenshtein augmentation was tested using two state of the art models - transformer and sequence-to-sequence based recurrent neural networks with attention. Levenshtein augmentation demonstrated an increase performance over non-augmented, and conventionally SMILES randomization augmented data when used for training of baseline models. Furthermore, Levenshtein augmentation seemingly results in what we define as <i>attentional gain </i>– an enhancement in the pattern recognition capabilities of the underlying network to molecular motifs.</p>


2020 ◽  
Author(s):  
Saeed Nosratabadi ◽  
Amir Mosavi ◽  
Puhong Duan ◽  
Pedram Ghamisi ◽  
Ferdinand Filip ◽  
...  

This paper provides a state-of-the-art investigation of advances in data science in emerging economic applications. The analysis was performed on novel data science methods in four individual classes of deep learning models, hybrid deep learning models, hybrid machine learning, and ensemble models. Application domains include a wide and diverse range of economics research from the stock market, marketing, and e-commerce to corporate banking and cryptocurrency. Prisma method, a systematic literature review methodology, was used to ensure the quality of the survey. The findings reveal that the trends follow the advancement of hybrid models, which, based on the accuracy metric, outperform other learning algorithms. It is further expected that the trends will converge toward the advancements of sophisticated hybrid deep learning models.


2021 ◽  
Vol 13 (8) ◽  
pp. 1602
Author(s):  
Qiaoqiao Sun ◽  
Xuefeng Liu ◽  
Salah Bourennane

Deep learning models have strong abilities in learning features and they have been successfully applied in hyperspectral images (HSIs). However, the training of most deep learning models requires labeled samples and the collection of labeled samples are labor-consuming in HSI. In addition, single-level features from a single layer are usually considered, which may result in the loss of some important information. Using multiple networks to obtain multi-level features is a solution, but at the cost of longer training time and computational complexity. To solve these problems, a novel unsupervised multi-level feature extraction framework that is based on a three dimensional convolutional autoencoder (3D-CAE) is proposed in this paper. The designed 3D-CAE is stacked by fully 3D convolutional layers and 3D deconvolutional layers, which allows for the spectral-spatial information of targets to be mined simultaneously. Besides, the 3D-CAE can be trained in an unsupervised way without involving labeled samples. Moreover, the multi-level features are directly obtained from the encoded layers with different scales and resolutions, which is more efficient than using multiple networks to get them. The effectiveness of the proposed multi-level features is verified on two hyperspectral data sets. The results demonstrate that the proposed method has great promise in unsupervised feature learning and can help us to further improve the hyperspectral classification when compared with single-level features.


Author(s):  
J.M. Murray ◽  
P. Pfeffer ◽  
R. Seifert ◽  
A. Hermann ◽  
J. Handke ◽  
...  

Objective: Manual plaque segmentation in microscopy images is a time-consuming process in atherosclerosis research and potentially subject to unacceptable user-to-user variability and observer bias. We address this by releasing Vesseg a tool that includes state-of-the-art deep learning models for atherosclerotic plaque segmentation. Approach and Results: Vesseg is a containerized, extensible, open-source, and user-oriented tool. It includes 2 models, trained and tested on 1089 hematoxylin-eosin stained mouse model atherosclerotic brachiocephalic artery sections. The models were compared to 3 human raters. Vesseg can be accessed at https://vesseg .online or downloaded. The models show mean Soerensen-Dice scores of 0.91±0.15 for plaque and 0.97±0.08 for lumen pixels. The mean accuracy is 0.98±0.05. Vesseg is already in active use, generating time savings of >10 minutes per slide. Conclusions: Vesseg brings state-of-the-art deep learning methods to atherosclerosis research, providing drastic time savings, while allowing for continuous improvement of models and the underlying pipeline.


2021 ◽  
Author(s):  
Phongsathorn Kittiworapanya ◽  
Kitsuchart Pasupa ◽  
Peter Auer

<div>We assessed several state-of-the-art deep learning algorithms and computer vision techniques for estimating the particle size of mixed commercial waste from images. In waste management, the first step is often coarse shredding, using the particle size to set up the shredder machine. The difficulty is separating the waste particles in an image, which can not be performed well. This work focused on estimating size by using the texture from the input image, captured at a fixed height from the camera lens to the ground. We found that EfficientNet achieved the best performance of 0.72 on F1-Score and 75.89% on accuracy.<br></div>


2021 ◽  
Author(s):  
Noor Ahmad ◽  
Muhammad Aminu ◽  
Mohd Halim Mohd Noor

Deep learning approaches have attracted a lot of attention in the automatic detection of Covid-19 and transfer learning is the most common approach. However, majority of the pre-trained models are trained on color images, which can cause inefficiencies when fine-tuning the models on Covid-19 images which are often grayscale. To address this issue, we propose a deep learning architecture called CovidNet which requires a relatively smaller number of parameters. CovidNet accepts grayscale images as inputs and is suitable for training with limited training dataset. Experimental results show that CovidNet outperforms other state-of-the-art deep learning models for Covid-19 detection.


2020 ◽  
Author(s):  
Saeed Nosratabadi ◽  
Amir Mosavi ◽  
Puhong Duan ◽  
Pedram Ghamisi ◽  
Filip Ferdinand ◽  
...  

Abstract This paper provides the state of the art of data science in economics. Through a novel taxonomy of applications and methods advances in data science are investigated. The data science advances are investigated in three individual classes of deep learning models, ensemble models, and hybrid models. Application domains include stock market, marketing, E-commerce, corporate banking, and cryptocurrency. Prisma method, a systematic literature review methodology is used to ensure the quality of the survey. The findings revealed that the trends are on advancement of hybrid models as more than 51% of the reviewed articles applied hybrid model. On the other hand, it is found that based on the RMSE accuracy metric, hybrid models had higher prediction accuracy than other algorithms. While it is expected the trends go toward the advancements of deep learning models.


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