scholarly journals Hyperoxaluria, Hypocitraturia, Hypomagnesiuria, and Lack of Intestinal Colonization by Oxalobacter formigenes in a Cervical Spinal Cord Injury Patient with Suprapubic Cystostomy, Short Bowel, and Nephrolithiasis

TSW Urology ◽  
2006 ◽  
Vol 1 ◽  
pp. 108-115
Author(s):  
Subramanian Vaidyanathan ◽  
Gerd E. von Unruh ◽  
Ian D. Watson ◽  
Norbert Laube ◽  
Steve Willets ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-4
Author(s):  
Subramanian Vaidyanathan ◽  
Bakul M. Soni ◽  
Tun Oo ◽  
Peter L. Hughes ◽  
Gurpreet Singh

Neuropathic urinary bladder is often colonised by multidrug-resistant bacteria. We report a 64-year-old male spinal cord injury patient with paraplegia, who received gentamicin on empirical basis before undergoing suprapubic cystostomy, as antibiotic sensitivity report of urine was not available. This patient developed fulminate septicaemia. Although appropriate antibiotic therapy (meropenem) was started when this patient manifested features of sepsis, acute renal failure occurred and he expired. Inappropriate initial antimicrobial therapy was the major contributory factor for this patient's mortality. Learning points from this case are (1) never do a cystostomy without prior urine culture and appropriate antibiogram; (2) in a chronic spinal cord injury patient, full blood count, liver function tests, albumin level, and albumin to globulin ratio should be performed before any surgical procedure.


Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
pp. 6866 ◽  
Author(s):  
Subramanian Vaidyanathan ◽  
Peter L Hughes ◽  
Bakul M Soni ◽  
Gurpreet Singh ◽  
Paul Mansour

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Subramanian Vaidyanathan ◽  
Paul Mansour ◽  
Peter L. Hughes ◽  
Fahed Selmi ◽  
Gurpreet Singh ◽  
...  

A male tetraplegic patient with, who had been taking warfarin, developed haematuria. Ultrasound scan revealed no masses, stones, or hydronephrosis. Urinary bladder had normal configuration with no evidence of masses or organised haematoma. Urine cytology revealed no malignant cells. Four months later, CT urography revealed an irregular mass at the base of urinary bladder. Cystoscopic biopsy revealed moderately differentiated adenocarcinoma, which contained goblet cells and pools of mucin showing strongly positive immunostaining for prostatic acid hosphatase and patchy staining for prostate specific antigen. Computed Tomography revealed multiple hypodense hepatic lesions and several osteolytic areas in femoral heads and iliac bone. With a presumptive diagnosis of prostatic carcinoma, leuprorelin acetate 3.75 mg was prescribed. This patient expired a month later.Conclusion. (i) Spinal cord injury patient, who passed blood in urine while taking warfarin, requiresrepeatedinvestigations to look for urinary tract neoplasm. (ii) Anti-androgen therapy should be prescribed for 2 weeks prior to administration of gonadorelin analogue to prevent tumour flare causing bone pain, bladder outlet obstruction, uraemia, and cardiovascular risk due to hypercoagulability associated with a rapid increase in tumour burden. (iii) Spinal cord physicians should adopt a caring and compassionate approach while managing tetraplegic patients with several co-morbidities, as aggressive diagnostic tests and therapeutic procedures may lead to deterioration in the quality of life.


Spinal Cord ◽  
2004 ◽  
Vol 42 (2) ◽  
pp. 134-135 ◽  
Author(s):  
S Vaidyanathan ◽  
J W H Watt ◽  
G Singh ◽  
P L Hughes ◽  
F Selmi ◽  
...  

PM&R ◽  
2012 ◽  
Vol 4 ◽  
pp. S357-S357
Author(s):  
Jackson Cohen ◽  
Junney M. Baeza Dager ◽  
Jamil Bashir ◽  
Kevin L. Dalal ◽  
Alberto Panero ◽  
...  

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