scholarly journals Severe Irritant Contact Dermatitis Causing Skin Ulceration Secondary to a Testosterone Patch

2009 ◽  
Vol 9 ◽  
pp. 333-338 ◽  
Author(s):  
Nathan Lawrentschuk ◽  
Neil Fleshner
Keyword(s):  
Contact Dermatitis ◽  
Side Effects ◽  
Management Strategies ◽  
Topical Administration ◽  
Older Men ◽  
Testosterone Replacement ◽  
Testosterone Replacement Therapy ◽  
Irritant Contact Dermatitis ◽  
The Past ◽  
Low Testosterone

Testosterone replacement has undergone somewhat of a revolution in the past decade with the introduction of topical administration techniques, including patches and gels, as well as an increasing interest in the treatment of older men with low testosterone levels for what is now termed andropause. Increasingly, testosterone replacement therapy is being individually tailored. Side effects to skin patches have been reported with irritant contact dermatitis being the most common. However, ulceration has previously not been reported. Herein, we present a case that highlights testosterone transdermal therapies, their potential side effects and management strategies, and broadens our knowledge as we approach an era where these types of treatments are likely to be more common.

Testosterone replacement in normal and pathologic prostate

2012 ◽  
Vol 11 (3) ◽  
Author(s):  
Mohit Khera
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Replacement Therapy ◽  
Rapid Growth ◽  
Prostatic Hyperplasia ◽  
Testosterone Replacement ◽  
Testosterone Replacement Therapy ◽  
The Past ◽  
The Usa ◽  
Low Testosterone

AbstractThe testosterone replacement therapy (TRT) market has grown rapidly over the past 5 years. Exogenous testosterone in various forms is now the fastest-growing medication prescribed in the USA. From 2005 to 2009, spending on testosterone jumped 115.5%, and the number of prescriptions filled increased 64.5%. One of the main reasons for this rapid growth in the TRT market is decreased concern that TRT can lead to prostate cancer. Other reasons are decreased concerns that testosterone can lead to worsening of benign prostatic hyperplasia (BPH) symptoms. In fact, recent studies suggest that TRT may improve BPH symptoms. Although there have been marked increases in the treatment of low testosterone, lingering concerns about prostate cancer have hindered progress. There are many theories, such as the prostate saturation theory, that may help us understand why testosterone may be safely administered in men with hypogonadism with normal and pathologic prostatic disease.

scholarly journals Fluctuating Palmar Erythema in a Toddler during COVID-19 Pandemic: Do You Know the Offender?

2021 ◽  
Vol 67 (1) ◽  
Author(s):  
Prateek Kumar Panda ◽  
Indar Kumar Sharawat
Keyword(s):  
Contact Dermatitis ◽  
Atypical Presentation ◽  
Irritant Contact Dermatitis ◽  
History Taking ◽  
Hand Sanitizer ◽  
The Past ◽  
Palmar Erythema ◽  
Complete Reversal ◽  
Bright Color ◽  
Careful History

Abstract Palmar erythema in children can be due to various reasons, such as chronic liver disease, rheumatological disorders, medications, irritant contact dermatitis and atopic dermatitis. Recently, there are few reports about contact dermatitis caused by frequent, daily use of hand sanitizers during this COVID-19 pandemic. A 3-year-old toddler brought with the concern of waxing-waning bilateral palmar erythema for the past 2 weeks. The parents revealed that the child liked the bright color of a recently bought hand sanitizer bottle so much he used to wash his hands every 20–30 min throughout the day. The atypical presentation of contact dermatitis might be because the child was using the sanitizer more frequently during the daytime. The dermatitis resolved with stopping excessive use of the hand sanitizer by the toddler. Clinicians should be aware of contact dermatitis during these pandemic times. Instead of investigating them extensively, careful history taking and merely advising them to judicially utilize the sanitizer can lead to complete reversal of symptoms.

Cardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study

2019 ◽  
Vol 132 (9) ◽  
pp. 1069-1077.e4 ◽  
Author(s):  
Simone Y. Loo ◽  
Laurent Azoulay ◽  
Rui Nie ◽  
Sophie Dell’Aniello ◽  
Oriana Hoi Yun Yu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Replacement Therapy ◽  
Testosterone Replacement ◽  
Testosterone Replacement Therapy ◽  
Testosterone Levels ◽  
Aging Men ◽  
Low Testosterone
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