scholarly journals Focal Cryoablation of Prostate: A Review

2008 ◽  
Vol 8 ◽  
pp. 486-491 ◽  
Author(s):  
Duke K. Bahn ◽  
Paul D. Silverman

Current treatment options for men with early localized prostate cancer are either some form of radical therapy or active surveillance. Radical therapy is usually associated with significant adverse effects that might jeopardize a man's quality of life. Some observers believe that PSA screening has resulted in the over diagnosis and over treatment of prostate cancer. Many men are being diagnosed with an early stage, small volume, unifocal or unilateral prostate cancer but are reluctant to accept watchful waiting or active surveillance. Focal cryoablation is the less than complete ablation of the gland with ice. Based on review of the limited amount of material available in the current literature, focal cryoablation can provide acceptable cancer control while preserving sexual potency and urinary continence. Focal cryoablation may fill a void in the therapeutic options available to patients with unifocal or unilateral prostate cancer who have a strong desire to maintain their quality of life.

2012 ◽  
Vol 29 (7) ◽  
pp. 536-540 ◽  
Author(s):  
Hanna A. Zaghloul ◽  
Jose R. Murillo

Chemotherapy treatment options are limited for patients with castration-resistant prostate cancer (CRPC). The purpose of this study is to report treatment use and adverse effects (AEs) within the last three months of life in patients with CRPC. Of the 88 patients identified, 32% received treatment within 3 months of death, and documented AEs occurred in 25% of patients. Of those, neutropenia (18.3%), nausea/vomiting (18.3%), and febrile neutropenia (13.6%) were the most frequent. Results of this study show high treatment utility towards the end-of-life in patients with CRPC, with one fourth of patients experiencing AEs. Attention to health-related quality of life becomes increasingly important as new treatments appear to have small impact on survival, and AEs of those treatments may significantly impact patient quality of life.


2018 ◽  
Vol 73 (6) ◽  
pp. 859-867 ◽  
Author(s):  
Sam J. Egger ◽  
Ross J. Calopedos ◽  
Dianne L. O’Connell ◽  
Suzanne K. Chambers ◽  
Henry H. Woo ◽  
...  

Cancer ◽  
2007 ◽  
Vol 109 (11) ◽  
pp. 2239-2247 ◽  
Author(s):  
Mark S. Litwin ◽  
John L. Gore ◽  
Lorna Kwan ◽  
Judson M. Brandeis ◽  
Steve P. Lee ◽  
...  

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Alyssa Louis ◽  
Stacy Rush ◽  
Shabbir Alibhai ◽  
Andrew Matthew ◽  
Robin Kalnin ◽  
...  

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S8
Author(s):  
L. Venderbos ◽  
R. van den Bergh ◽  
M. Roobol ◽  
F. Schröder ◽  
E. Steyerberg ◽  
...  

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