scholarly journals The Role of the MRG Gene Family in Replicative Senescence and Immortalization

2001 ◽  
Vol 1 ◽  
pp. 66-66
Author(s):  
James K. Leung ◽  
Patricia Pardo ◽  
Olivia M. Pereira-Smith
Keyword(s):  
Gene Family ◽  
Replicative Senescence

scholarly journals THE ROLE OF THE MRG GENE FAMILY IN REPLICATIVE SENESCENCE AND IMMORTALIZATION

2001 ◽  
Vol 1 (S3) ◽  
pp. 66-66
Author(s):  
James K. Leung ◽  
Patricia Pardo ◽  
Olivia M. Pereira-Smith
Keyword(s):  
Gene Family ◽  
Replicative Senescence

scholarly journals Role of the Candida albicans MNN1 gene family in cell wall structure and virulence

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
Steven Bates ◽  
Rebecca A Hall ◽  
Jill Cheetham ◽  
Mihai G Netea ◽  
Donna M MacCallum ◽  
...  
Keyword(s):  
Cell Wall ◽  
Candida Albicans ◽  
Gene Family ◽  
Cell Wall Structure ◽  
Wall Structure

scholarly journals Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.

1990 ◽  
Vol 10 (2) ◽  
pp. 549-560 ◽  
Author(s):  
S A Nadin-Davis ◽  
A Nasim
Keyword(s):  
Gene Family ◽  
Fission Yeast ◽  
Mating Type ◽  
Growth Cycle ◽  
Yeast Cells ◽  
Null Alleles ◽  
Northern Analysis ◽  
Gene Transcript ◽  
Type Gene

We have further investigated the function of the ras1 and byr1 genes, which were previously shown to be critical for sexual differentiation in fission yeast cells. Several physiological similarities between strains containing null alleles of these genes supports the idea that ras1 and byr1 are functionally closely related. Furthermore, we have found that byr1 is allelic to ste1, one of at least 10 genes which when mutated can cause sterility. Since ras1 had previously been found to be allelic to ste5, both ras and byr genes are now clearly shown to be a part of the ste gene family, thus confirming their close functional relationship. The observation that the mating-type loci could overcome the sporulation block of ras1 and byr1 mutant strains prompted investigation of the role of the ras-byr pathway in the induction of the mating-type gene transcripts upon nitrogen starvation. By Northern analysis of RNA preparations from strains carrying wild-type or mutant ras1 alleles and grown to different stages of the growth cycle, we have shown that ras1 plays an important role in inducing the Pi transcript of the mating-type loci and the mei3 gene transcript. These observations provide a molecular basis for the role of the ste gene family, including ras1 and byr1, in meiosis and indicate that further characterization of other ste genes would be very useful for elucidating the mechanism of ras1 function in fission yeast cells.

Investigating the role of EGF-CFC gene family in recurrent pregnancy loss through bioinformatics and molecular approaches

2021 ◽  
pp. 1-13
Author(s):  
João Matheus Bremm ◽  
Juliano André Boquett ◽  
Marcus Silva Michels ◽  
Thayne Woycinck Kowalski ◽  
Flávia Gobetti Gomes ◽  
...  
Keyword(s):  
Gene Family ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Molecular Approaches

Role of CCN, a vertebrate specific gene family, in development

2008 ◽  
Vol 51 (1) ◽  
pp. 55-67 ◽  
Author(s):  
Ken-ichi Katsube ◽  
Kei Sakamoto ◽  
Yoshihiro Tamamura ◽  
Akira Yamaguchi
Keyword(s):  
Gene Family ◽  
Specific Gene

Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes

1990 ◽  
Vol 10 (2) ◽  
pp. 549-560
Author(s):  
S A Nadin-Davis ◽  
A Nasim
Keyword(s):  
Gene Family ◽  
Fission Yeast ◽  
Mating Type ◽  
Growth Cycle ◽  
Yeast Cells ◽  
Null Alleles ◽  
Northern Analysis ◽  
Gene Transcript ◽  
Type Gene

We have further investigated the function of the ras1 and byr1 genes, which were previously shown to be critical for sexual differentiation in fission yeast cells. Several physiological similarities between strains containing null alleles of these genes supports the idea that ras1 and byr1 are functionally closely related. Furthermore, we have found that byr1 is allelic to ste1, one of at least 10 genes which when mutated can cause sterility. Since ras1 had previously been found to be allelic to ste5, both ras and byr genes are now clearly shown to be a part of the ste gene family, thus confirming their close functional relationship. The observation that the mating-type loci could overcome the sporulation block of ras1 and byr1 mutant strains prompted investigation of the role of the ras-byr pathway in the induction of the mating-type gene transcripts upon nitrogen starvation. By Northern analysis of RNA preparations from strains carrying wild-type or mutant ras1 alleles and grown to different stages of the growth cycle, we have shown that ras1 plays an important role in inducing the Pi transcript of the mating-type loci and the mei3 gene transcript. These observations provide a molecular basis for the role of the ste gene family, including ras1 and byr1, in meiosis and indicate that further characterization of other ste genes would be very useful for elucidating the mechanism of ras1 function in fission yeast cells.

Sign in / Sign up

Export Citation Format

Share Document