scholarly journals Prospective Study of Antibiotic Prophylaxis for Prostate Biopsy Involving >1100 Men

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Rustom P. Manecksha ◽  
Gregory J. Nason ◽  
Ivor M. Cullen ◽  
Jérôme P. Fennell ◽  
Elizabeth McEvoy ◽  
...  
Keyword(s):  
Prospective Study ◽  
Antibiotic Prophylaxis ◽  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Multidrug Resistant ◽  
Infection Rates ◽  
Ultrasound Guided ◽  
E Coli ◽  
Positive Urine ◽  
Febrile Episodes

We aimed to compare infection rates for two 3-day antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy (TRUSgbp) and demonstrate local microbiological trends. In 2008, 558 men and, in 2009, 625 men had TRUSgpb. Regimen 1 (2008) comprised 400 mg Ofloxacin immediately before biopsy and 200 mg 12-hourly for 3 days. Regimen 2 (2009) comprised Ofloxacin 200 mg 12-hourly for 3 days commencing 24 hours before biopsy. 20/558 (3.6%) men had febrile episodes with regimen 1 and 10/625 (1.6%) men with regimen 2 ().E. coliwas the most frequently isolated organism. Overall, 7/13 (54%) of positive urine cultures were quinolone resistant and (5/13) 40% were multidrug resistant. Overall, 5/9 (56%) patients with septicaemia were quinolone resistant. All patients were sensitive to Meropenem. There was 1 (0.2%) death with regimen 1. Commencing Ofloxacin 24 hours before TRUSgpb reduced the incidence of febrile episodes significantly. We observed the emergence of quinolone and multidrug-resistantE. coli. Meropenem should be considered for unresolving sepsis.

scholarly journals Quinolone Prophylaxis in Transrectal Ultrasound Guided Prostate Biopsy: An Eight-Year Single Center Experience

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Bing-Juin Chiang ◽  
Yeong Shiau Pu ◽  
Shiu-Dong Chung ◽  
Shih-Ping Liu ◽  
Hong-Jeng Yu ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Infectious Complications ◽  
Pipemidic Acid ◽  
Ultrasound Guided ◽  
E Coli ◽  
Single Center Experience ◽  
Significant Difference ◽  
Group A ◽  
Group B

We retrospectively evaluated the efficacy of prophylaxis with pipemidic acid and levofloxacin in transrectal ultrasound guided prostate biopsy (TRUSP-Bx). From January 2002 to December 2004, patients receiving oral pipemidic acid 500 mg twice daily for three days with or without a preoperative intravenous cefazolin 1 gm injection comprised group A. Between January 2005 and December 2009, patients receiving oral levofloxacin 500 mg one hour before biopsy comprised group B. We calculated the annual febrile urinary tract infection (fUTI) rates. Patients’ characteristics, including age, prophylactic antibiotics, biopsy core numbers, pathologic results, PSA, and the spectrums and susceptibility of pathogens, were also evaluated. A total of 1313 (35.5%) patients belonged to group A, while 2381 (64.5%) patients belonged to group B. Seventy-three patients experienced postoperative infectious complications. There was a significant difference in the fUTI rate between groups A and B (3.7% versus 1.0%,P<0.001). The yearly fUTI rates varied from 0.6 to 3.9% between 2002 and 2009. Of the 73 patients with fUTI, those receiving levofloxacin prophylaxis were more likely to harbor fluoroquinolone-resistant pathogens (P<0.001).E. coliwas the most common pathogen in both groups. Levofloxacin remains effective and appears superior to pipemidic acid based prophylaxis.

Rectal Cultures Before Transrectal Ultrasound-guided Prostate Biopsy Reduce Post-prostatic Biopsy Infection Rates

Urology ◽  
2012 ◽  
Vol 79 (3) ◽  
pp. 556-563 ◽  
Author(s):  
Christopher A. Duplessis ◽  
Mary Bavaro ◽  
Mark P. Simons ◽  
Charles Marguet ◽  
Michael Santomauro ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Infection Rates ◽  
Ultrasound Guided ◽  
Prostatic Biopsy

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

2006 ◽  
Vol 16 (4) ◽  
pp. 939-943 ◽  
Author(s):  
Jordi Puig ◽  
Anna Darnell ◽  
Patricia Bermúdez ◽  
Antoni Malet ◽  
Guadalupe Serrate ◽  
...  
Keyword(s):  
Antibiotic Prophylaxis ◽  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Ultrasound Guided

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

2006 ◽  
Vol 30 (5) ◽  
pp. 374-375
Author(s):  
J. Puig ◽  
A. Darnell ◽  
P. Bermúdez ◽  
A. Malet ◽  
G. Serrate ◽  
...  
Keyword(s):  
Antibiotic Prophylaxis ◽  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Ultrasound Guided

MP25-03 FOSFOMYCIN FOR ANTIBIOTIC PROPHYLAXIS PRIOR TO TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY

2015 ◽  
Vol 193 (4S) ◽  
Author(s):  
Andrew Colhoun ◽  
Jay Sulek ◽  
Zachary McDowell ◽  
Michael Climo ◽  
B. Mayer Grob
Keyword(s):  
Antibiotic Prophylaxis ◽  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Ultrasound Guided
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