scholarly journals Effect of Magnesium Supplementation on the Distribution Patterns of Zinc, Copper, and Magnesium in Rabbits Exposed to Prolonged Cadmium Intoxication

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Zorica Bulat ◽  
Danijela Đukić-Ćosić ◽  
Biljana Antonijević ◽  
Petar Bulat ◽  
Dragana Vujanović ◽  
...  

The present study is designed to investigate whether magnesium (Mg) supplementation may prevent Cd-induced alterations in zinc (Zn), copper (Cu), and magnesium (Mg) status in rabbits. For this purpose, the concentrations of Zn, Cu, and Mg were estimated in blood, urine, and organs (brain, heart, lungs, liver, kidney, spleen, pancreas, skeletal muscle, and bone) of rabbits given Cd (10 mg/kg b.w.) and rabbits cotreated with Mg (40 mg/kg b.w.) orally, as aqueous solutions of Cd chloride and Mg acetate every day for 4 weeks. Samples were mineralized with conc. HNO3and HClO4(4:1) and metals concentrations were determined by atomic absorption spectrophotometry (AAS). Magnesium supplementation succeeded to overcome Cd-induced disbalance of investigated bioelements. Beneficial effects of Mg were observed on Zn levels in blood and urine, on Cu levels in urine, and on Mg levels in blood. Magnesium pretreatment also managed to counteract or reduce all Cd-induced changes in levels of Cu and Mg in organs, while it did not exert this effect on Zn levels. These findings suggest that enhanced dietary Mg intake during Cd exposure can have at least partly beneficial effect on Cd-induced alterations in homeostasis of zinc, copper, and magnesium.

2017 ◽  
Vol 68 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Zorica Bulat ◽  
Danijela Đukić-Ćosić ◽  
Biljana Antonijević ◽  
Aleksandra Buha ◽  
Petar Bulat ◽  
...  

Abstract The study was designed to investigate the influence of zinc (Zn) supplementation on cadmium-induced alterations in zinc, copper (Cu), and magnesium (Mg) status in rabbits. For this purpose, the concentrations of cadmium (Cd), Zn, Cu, and Mg were estimated in the blood, liver, kidney, and bone. The rabbits were divided in a control group, a Cd group-animals intoxicated orally with Cd (10 mg kg-1 bw, as aqueous solution of Cd-chloride), and a Cd+Zn group-animals intoxicated with the same dose of Cd and co-treated with Zn (20 mg kg-1 bw, as aqueous solution of Zn-sulphate). Solutions were administered orally, every day for 28 days. Sample mineralisation was performed with concentrated nitric acid (HNO3) and perchloric acid (HClO4) (4:1) and metal concentrations were determined by atomic absorption spectrophotometry (AAS). Zinc supplementation improved some of Cd-induced disturbances in bioelement levels in the investigated tissues. Beneficial effects of Zn on Zn and Cu levels were observed in blood, as well as on the Cu kidney level. The calculated values for Cu/Zn, Mg/Zn, and Mg/Cu ratios in blood suggest that Zn co-treatment reduces Cd-induced changes in bioelement ratios in blood.


2021 ◽  
Vol 7 ◽  
Author(s):  
Emily V. Bushby ◽  
Louise Dye ◽  
Lisa M. Collins

In commercial pig production, stressful events are common and can have detrimental impacts on the pig's health and welfare, as well as on the performance of the farm. Supplementary magnesium may reduce stress, and subsequent harmful and aggressive behaviors, that occur during stressful events, such as regrouping. However, reports on the efficacy of this treatment are mixed. We aimed to systematically review the studies in which magnesium was given to pigs to examine the effects on measures of stress. Of the 16 studies included in the final corpus, 10 reported at least one statistically significant beneficial effect of supplementary magnesium on reducing stress. However, two studies found that magnesium significantly increased stress suggesting supplementary dietary magnesium may be harmful in some cases. Overall, there are a limited number of studies investigating the possible effect of magnesium on reducing stress in pigs, and although results were varied, the majority found beneficial effects of supplementary magnesium.


1971 ◽  
Vol 17 (7) ◽  
pp. 614-621 ◽  
Author(s):  
John A Lott ◽  
Thomas S Herman

Abstract We have studied calcium and magnesium determination with the AutoAnalyzer, using dialysis, and measurement by atomic absorption spectrophotometry. The fraction of calcium and magnesium that dialyzes is proportional to the protein content of the sample; therefore an error is introduced when aqueous solutions of calcium or magnesium salts are used as standards. Apparently, the presence of proteins causes increased dialysis of Ca+2 and Mg+2.


2016 ◽  
Vol 13 (3) ◽  
pp. 482-488
Author(s):  
Baghdad Science Journal

In this study, the adsorption of Zn (NO3)2 is carried out by using surfaces of malvaparviflora. The validity of the adsorption is evaluated by using atomic absorption Spectrophotometry through determination the amount of adsorbed Zn (NO3)2. Various parameters such as PH, adsorbent weight and contact time are studied in terms of their effect on the reaction progress. Furthermore, Lagergren’s equation is used to determine adsorption kinetics. It is observed that high removal of Zn (NO3)2 is obtained at PH=2. High removal of Zn (NO3)2 is at the time equivalent of 60 min and reaches equilibrium,where 0.25gm is the best weight of adsorbant . For kinetics the reaction onto malvaparviflora follows pseudo first order Lagergren’s equation.


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Rizki Andalia ◽  
Mulia Aria Suzanni ◽  
Rini Rini

Lipstick or lip dye is a cosmetic dose that serves to coloring, decorative the lips, as a moisturizing material and protect the lips from exposure the sun to provide optimum results. Lipstick should not contain chemicals such as lead (Pb) because the Pb is a heavy metal that is very dangerous when continuously used on the skin, because it will be absorbed into the blood and attack the body organ causing the onset of disease. According to BPOM that the lead rate on the lipstick does not exceed the permissible limit of 20 mg/kg or 20 ppm.This research aims to know the levels contained in the samples are 4 brands of matte lipstick that are sold in the Aceh market in Banda Aceh City with the method of atomic absorption spectrophotometry (AAS). The results showed that on the 4 brands of lipstick matte contain heavy metal lead (Pb) with a rate still qualified allowed by BPOM  is samples A, B, C, and D, respectively at 0.24 ppm; 0.10 ppm; 2.87 ppm and 1.32 ppm, so that the 4 brands of lipstick matte are still used.


2020 ◽  
Vol 6 (1) ◽  
pp. 087
Author(s):  
Rosy Hutami ◽  
M Fakih Kurniawan ◽  
Henna Khoerunnisa

Sumedang tofu is one of favorite foods for Indonesian society. But many sellers or producers are not aware to the food safety of sumedang tofu. The aims of this study were to analyze the microbial, formalin, and lead (Pb) contents in ready-to-eat sumedang tofu which were sold in traffic jams area in Cicurug, Ciawi, and Cisarua. The analysis were carried out by Total Plate Count (TPC) testing for microbial analysis, potassium permanganate reaction (KMnO4) testing for formaldehyde analysis, and atomic absorption spectrophotometry (AAS) method for lead content analysis in the samples. The results obtained for the microbial analysis were sumedang tofu that were sold in the traffic jam areas of Cicurug, Ciawi, and Cisarua contained contaminant above the treshold (1.4 x 105 colonies / gram to 2.2 x 105 colonies / gram of microbes). All of the samples of sumedang tofu were positive containing formaldehyde. Otherwise, there were no lead (Pb) content in all samples regarding to AAS analysis. This study concluded that the ready-to-eat sumedang tofu those were sold in traffic jam area in the Cicurug, Ciawi, and Cisarua were not suitable for consumption because it contained exceed microbial contamination and formalin which are harmful for human health.Keywords : formalin, microbes, sumedang tofu, lead, traffic jam


2019 ◽  
Author(s):  
Chem Int

A significant flux of heavy metals, among other toxins, reaches the lungs through smoking. This study reports Cd, Pb, Cu and Zn contents in tobacco of 11 brands of cigarette commonly sold in Ethiopia. The heavy metals were determined by atomic absorption spectrophotometry after wet digestion of cigarette tobacco using HNO3 and H2O2. The concentration of trace metals in the cigarettes ranged (mean) (μg/g), Cd: 1.3−7.6 (2.48±0.32), Pb: 0.50−12.50 (6.24±2.2), Cu: 2.89−25.35 (13.70±4.12) and Zn: 24.40−62.55 (36.22±7.50) while Ni was not detected in all the eleven brands of cigarettes. Comparable levels of trace metals were obtained in the tobacco of both imported and Ethiopian cigarettes. The average trace metal contents of cigarettes available in Ethiopia were Cd 1.82±0.39, Pb 4.23±0.97, Cu 10.2±3.1 and Zn 28.2±7.8 μg/cigarette and a person who smokes 20 cigarettes per day is estimated to increase his/her daily Cd, Pb, Cu and Zn retention by approximately 0.036, 0.085, 0.204, 0.564 mg/day, respectively. The results indicate that smoking and exposure to cigarette smoke is a serious problem to be taken into account when carrying out epidemiological studies on human exposure to trace metals.


2015 ◽  
Vol 1 (1) ◽  
pp. 41
Author(s):  
Bella Santa Rossi ◽  
Paryanti Paryanti ◽  
Yuli Ristianingsih ◽  
Abubakar Tuhuloula

Pewarnaan pada proses produksi kain sasirangan menghasilkan limbah yang mengandung logam berat, diantaranya adalah timbal (Pb2+) dan kadmium (Cd2+). Penelitian ini bertujuan untuk mengetahui pengaruh proses fitoremediasi terhadap konsentrasi logam Pb2+ dan Cd2+ dari limbah cair industri sasirangan di Kalimantan Selatan, serta mengetahui pertambahan berat basah eceng gondok. Eceng gondok yang sudah dibersihkan dan diaklimatisasi ditanam dalam reaktor berisi larutan limbah dengan konsentrasi 3% (v/v); 9% (v/v); dan 15% (v/v). Sampel diambil setiap 2 hari sekali sebanyak 100 ml dan dianalisis menggunakan AAS (Atomic Absorption Spectrophotometry). Hasil penelitian ini menunjukkan bahwa konsentrasi logam Pb2+ dan Cd2+ dalam limbah setelah proses fitoremediasi terjadi penurunan. Kadar Pb2+ pada konsentrasi 3% (v/v) semula 0,197 ppm menjadi 0,062 ppm, pada konsentrasi 9% (v/v) semula 0,200 ppm menjadi 0,077 ppm dan untuk 15% (v/v) adalah 0,225 ppm menjadi 0,093 ppm. Sedangkan untuk Cd2+ konsentrasi 3% (v/v) semula 0,110 ppm menjadi 0,059 ppm, konsentrasi 9% (v/v) adalah 0,127 ppm menjadi 0,045 ppm dan untuk konsentrasi 15% (v/v) semula 0,144 ppm menjadi 0,047 ppm.


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