scholarly journals Highlights of Thirty-Year Experience of Laser Use at the Florence (Italy) Department of Dermatology

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Piero Campolmi ◽  
Paolo Bonan ◽  
Giovanni Cannarozzo ◽  
Andrea Bassi ◽  
Nicola Bruscino ◽  
...  
Keyword(s):  
Gold Standard ◽  
Thermal Damage ◽  
Soft Tissues ◽  
Continuous Wave ◽  
Healing Time ◽  
Easy Access ◽  
Hypertrophic Scars ◽  
Cytologic Examination ◽  
The Past ◽  
Higher Power

The CO2laser has been used extensively in dermatological surgery over the past 30 years and is now recognised as the gold standard for soft tissue vaporization. Considering that the continuous wave CO2laser delivery system and the newer “superpulsed” and scanned CO2systems have progressively changed our practice and patient satisfaction, a long range documentation can be useful. Our experience has demonstrated that the use of CO2laser involves a reduced healing time, an infrequent need for anaesthesia, reduced thermal damage, less bleeding, less inflammation, the possibility of intra-operative histologic and/or cytologic examination, and easy access to anatomically difficult areas. Immediate side effects have been pain, erythema, edema, typically see with older methods, using higher power. The percentage of after-treatment keloids and hypertrophic scars observed was very low (~1%) especially upon the usage of lower parameters. The recurrence of viral lesions (condylomas and warts) have been not more frequent than those due to other techniques. Tumor recurrence is minor compared with radiotherapy or surgery. This method is a valid alternative to surgery and/or diathermocoagulation for microsurgery of soft tissues. Our results are at times not consistent with those published in the literature, stressing the concept that multicentric studies that harmonization methodology and the patient selection are vital.

Rapid Critical Point Drying of Tissues in a Parr Bomb

1972 ◽  
Vol 30 ◽  
pp. 400-401
Author(s):  
C.A. Baechler ◽  
W. C. Pitchford ◽  
J. M. Riddle ◽  
C.B. Boyd ◽  
H. Kanagawa ◽  
...  
Keyword(s):  
Critical Point ◽  
Critical Pressure ◽  
Soft Tissues ◽  
Biological Tissues ◽  
Critical Temperatures ◽  
Air Drying ◽  
The Past ◽  
Critical Point Drying ◽  
Great Stress ◽  
Infiltration Techniques

Preservation of the topographic ultrastructure of soft biological tissues for examination by scanning electron microscopy has been accomplished in the past by using lengthy epoxy infiltration techniques, or dehydration in ethanol or acetone followed by air drying. Since the former technique requires several days of preparation and the latter technique subjects the tissues to great stress during the phase change encountered during air-drying, an alternate rapid, economical, and reliable method of surface structure preservation was developed. Turnbill and Philpott had used a fluorocarbon for the critical point drying of soft tissues and indicated the advantages of working with fluids having both moderately low critical pressures as well as low critical temperatures. Freon-116 (duPont) which has a critical temperature of 19. 7 C and a critical pressure of 432 psi was used in this study.

Sending out Biased Signals: an Appropriate Proposition for Pain?

2019 ◽  
Vol 32 (2) ◽  
pp. 108-110 ◽  
Author(s):  
E. Besserer-Offroy ◽  
P. Sarret
Keyword(s):  
Side Effects ◽  
Acute Pain ◽  
Gold Standard ◽  
Pain Treatment ◽  
Opioid Analgesics ◽  
Mu Opioid Receptor ◽  
Clinical Development ◽  
Mu Opioid ◽  
Development Stages ◽  
The Past

In the past few years, several biased ligands acting at the mu-opioid receptor were reported in the literature. These agonists are aimed at reducing pain while having fewer side effects than morphine, the gold standard of opioid analgesics. In this mini-review, we describe and discuss the recent advances in mu-biased ligands actually in preclinical and clinical development stages, including the latest U.S. Food and Drug Administration review of oliceridine, a biased mu-agonist for moderate to severe acute pain treatment developed by the company Trevena.

scholarly journals UAV Forensics: DJI Mini 2 Case Study

Drones ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 49
Author(s):  
Miloš Stanković ◽  
Mohammad Meraj Mirza ◽  
Umit Karabiyik
Keyword(s):  
Law Enforcement ◽  
Federal Aviation Administration ◽  
Easy Access ◽  
Law Enforcement Agencies ◽  
The Past ◽  
Personally Identifiable Information ◽  
Multiple Devices ◽  
Forensic Tools ◽  
Recreational Use

Rapid technology advancements, especially in the past decade, have allowed off-the-shelf unmanned aerial vehicles (UAVs) that weigh less than 250 g to become available for recreational use by the general population. Many well-known manufacturers (e.g., DJI) are now focusing on this segment of UAVs, and the new DJI Mini 2 drone is one of many that falls under this category, which enables easy access to be purchased and used without any Part 107 certification and Remote ID registration. The versatility of drones and drone models is appealing for customers, but they pose many challenges to forensic tools and digital forensics investigators due to numerous hardware and software variations. In addition, different devices can be associated and used for controlling these drones (e.g., Android and iOS smartphones). Moreover, according to the Federal Aviation Administration (FAA), the adoption of Remote ID is not going to be required for people without the 107 certifications for this segment at least until 2023, which creates finding personally identifiable information a necessity in these types of investigations. In this research, we conducted a comprehensive investigation of DJI Mini 2 and its data stored across multiple devices (e.g., SD cards and mobile devices) that are associated with the drone. The aim of this paper is to (1) create several criminal-like scenarios, (2) acquire and analyze the created scenarios using leading forensics software (e.g., Cellebrite and Magnet Axiom) that are commonly used by law enforcement agencies, (3) and present findings associated with potential criminal activities.

scholarly journals Multifunctional Optical Crystals for All-Solid-State Raman Lasers

Crystals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 114
Author(s):  
Hui Zhao ◽  
Shibo Dai ◽  
Siqi Zhu ◽  
Hao Yin ◽  
Zhen Li ◽  
...  
Keyword(s):  
Solid State ◽  
Continuous Wave ◽  
Frequency Doubling ◽  
Raman Laser ◽  
Rare Earth Ions ◽  
Excellent Performance ◽  
The Past ◽  
Raman Lasers ◽  
Optical Crystals ◽  
Laser Crystals

In the past few decades, the multifunctional optical crystals for all-solid-state Raman lasers have been widely studied by many scholars due to their compactness, convenience and excellent performance. In this review, we briefly show two kinds of multifunctional Raman crystals: self-Raman (laser and Raman effects) crystals and self-frequency-doubled Raman (frequency-doubling and Raman effects) crystals. We firstly introduce the properties of the self-Raman laser crystals, including vanadate, tungstate, molybdate and silicate doped with rare earth ions, as well as self-frequency-doubled Raman crystals, including KTiOAsO4 (KTA) and BaTeMo2O9 (BTM). Additionally, the domestic and international progress in research on multifunctional Raman crystals is summarized in the continuous wave, passively Q-switched, actively Q-switched and mode-locked regimes. Finally, we present the bottleneck in multifunctional Raman crystals and the outlook for future development. Through this review, we contribute to a general understanding of multifunctional Raman crystals.

Real Bills, The Gold Standard, and Central Bank Policy

1976 ◽  
Vol 50 (4) ◽  
pp. 503-513 ◽  
Author(s):  
Robert Craig West
Keyword(s):  
Central Bank ◽  
Discount Rate ◽  
Real World ◽  
Federal Reserve ◽  
Economic Activity ◽  
Gold Standard ◽  
Government Regulation ◽  
International Exchange ◽  
The Real ◽  
The Past

Students of the origins and accomplishments of government regulation of economic activity have open suspected that the laws on which regulation is based were addressed to problems and conditions of the past that no longer prevailed, or — what is worse — assumptions about the “real world” that are highly unrealistic. This is Professor West's main conclusion about the Federal Reserve Act of 1913, especially as regards its discount rate and international exchange policies.

ROOT END FILLING MATERIALS – A REVIEW

2021 ◽  
pp. 5-9
Author(s):  
Bynagari Chandra Shekar ◽  
Veerendra Uppin ◽  
Madhu Pujar
Keyword(s):  
Root Canal ◽  
Gold Standard ◽  
The Past ◽  
Filling Materials ◽  
Restorative Materials ◽  
The Creation ◽  
Almost All

The aim of a root end lling is to prevent irritants from the root canal from leaking into the periapical region and to improve the apical seal created by nonsurgical endodontic care. Various restorative materials that have been used for coronal restorations have been tried and tested as root end lling materials, as well as the creation of restorative materials designed specically for root end lling. In the past, amalgam was the preferred material for root end lling. MTA, a recently established material that meets almost all of the criteria for an ideal root end lling material, has become the gold standard against which newer materials are measured. This article examines traditional endodontic root end materials and provides an overview of recent advancements in root end lling

scholarly journals The Clinical Concept of Fibromyalgia as a Changing Paradigm in the Past 20 Years

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Mary-Ann Fitzcharles ◽  
Muhammad B. Yunus
Keyword(s):  
Gold Standard ◽  
Standard Treatment ◽  
Good Health ◽  
Pain Processing ◽  
Predictors Of Outcome ◽  
Rational Treatment ◽  
The Past ◽  
Active Patient ◽  
Pharmacologic Treatments ◽  
Clinical Concept

Fibromyalgia (FMS) is a valid clinical condition that affects 2%–4% of the population with a pivot symptom of widespread body pain. The cause and cure of FMS are as yet unknown. The concept of FMS has evolved over the past two decades to incorporate symptoms beyond pain as contributing to the global spectrum of suffering. FMS is now recognized to be grounded in the neurological domain with evidence of dysregulation of pain processing. Appreciation of the neurophysiologic mechanisms operative in FMS has contributed to rational treatment recommendations, although a “gold standard treatment” does not currently exist. Ideal treatments for FMS patients should be individualized with emphasis on active patient participation, good health practices, and multimodal intervention, incorporating nonpharmacologic and pharmacologic treatments. Predictors of outcome, which is favourable in over 50% of patients, are unknown, but those with better outcome do more physical activity and use fewer medications.

scholarly journals Threshold of permanent cornea thermal damage due to incidental continuous wave CO2 laser irradiation

2010 ◽  
Vol 14 (2) ◽  
pp. 459-467 ◽  
Author(s):  
Mayada Tahir
Keyword(s):  
Laser Irradiation ◽  
Co2 Laser ◽  
Thermal Damage ◽  
Continuous Wave ◽  
Anterior Part ◽  
Outer Part ◽  
Human Cornea ◽  
Thermal Dose ◽  
Element Analysis ◽  
Reflex Blink

Cornea thermal damage due to incidental continuous wave CO2 laser irradiation is studied numerically based on bio-heat equation. The interaction of laser with tissue leads to a rapid temperature increased in target and the nearby tissue. As the temperature of the eye surface reaches 44?C, a sensation of pain will cause aversion response of the reflex blink and/or shifting away from the source of pain. The aim of the work is to predict numerically the threshold limit of incidental laser power that causes damage to the anterior part of the cornea, which can be healed within 2-5 days as long as damage is not exceeding the outer part of the eye (epithelium). A finite element analysis is used to predict temperature distribution through the cornea where the necroses region can be obtained using thermal dose equation. The thermal dose that required for damaging the cornea is predicted from previously published experimental data on rhesus monkeys and used later as a limit for shrinkage to human cornea. The result of this work is compared by international standard of safety and a good nearby result is obtained which verified the result of this work.

Anesthesia for Lung Transplantation

2019 ◽  
pp. 322-329
Author(s):  
J. Devin Roberts
Keyword(s):  
Lung Transplantation ◽  
Transesophageal Echocardiography ◽  
Gold Standard ◽  
Anesthetic Management ◽  
Survival Rates ◽  
Anesthesia Care ◽  
Lung Isolation ◽  
The Past ◽  
Lung Transplants ◽  
End Stage

Since the first human procedure in 1963, lung transplantation has become the gold standard treatment of a variety of end-stage lung diseases. With over 4000 lung transplants performed in 2015 and steadily improving survival rates over the past three decades, anesthetic management of patients undergoing lung transplant can significantly contribute to patient outcomes. Anesthesia care for lung transplantation can be both complex and clinically challenging. Anesthesiologists taking part in these procedures need to have specific skills regarding thoracic and cardiac anesthesia. There are both technical and physiological challenges, such as achieving adequate lung isolation and oxygenation, interpretation and use of transesophageal echocardiography, and the management of respiratory and myocardial impairments. This chapter provides an overview of these perioperative anesthetic management considerations utilizing a problem-based format.

scholarly journals The euro and the recent European crisis vis-à-vis the gold standard and the great depression: institutionalities, specificities and interfaces

2017 ◽  
Vol 37 (1) ◽  
pp. 147-166 ◽  
Author(s):  
GIULIANO CONTENTO DE OLIVEIRA ◽  
PAULO JOSÉ WHITAKER WOLF
Keyword(s):  
Great Depression ◽  
Gold Standard ◽  
Institutional Arrangements ◽  
European Countries ◽  
Lender Of Last Resort ◽  
Central European ◽  
The Past ◽  
The Great Depression ◽  
European Crisis ◽  
Harmful Effects

ABSTRACT The paper aims to establish interfaces between the Great Depression of the 1930s under the Gold Standard and the recent European Crisis under the Euro. It is argued that, despite their specificities, both crises revealed the potentially harmful effects, in economic and social terms, of institutional arrangements that considerably reduce the autonomy of monetary, fiscal and exchange rate policies of participating countries, without being accompanied by increased cooperation between them, which should be led by a global (in the case of the Great Depression) or regional (in the case of the European Crisis) hegemonic power, which is not only capable of, but is also willing to act as a buyer and lender of last resort, especially in circumstances characterized by increased uncertainty, the deterioration of the general state of expectations and increased liquidity preference. In fact, central European countries in the past and peripheral European countries nowadays were effectively pushed toward deflationary adjustments in which a reduction of prices and wages was accompanied by a reduction of output and employment levels. Thus, in the absence of the possibility of restoring the autonomy of economic policy, the overcome of the crisis necessarily requires, both before - under the Gold Standard - and nowadays - under the Euro -, joint actions aimed to assure that the responsibility for the adjustment will be equally distributed among all the economies, in order to avoid that some of them benefit at the expense of the others in this process.

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