scholarly journals Diffusion Tensor Imaging-Based Research on Human White Matter Anatomy

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Ming-guo Qiu ◽  
Jing-na Zhang ◽  
Ye Zhang ◽  
Qi-yu Li ◽  
Bing Xie ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Probability Maps ◽  
Chinese Visible Human ◽  
Human Dataset ◽  
Visible Human ◽  
Visible Human Dataset

The aim of this study is to investigate the white matter by the diffusion tensor imaging and the Chinese visible human dataset and to provide the 3D anatomical data of the corticospinal tract for the neurosurgical planning by studying the probabilistic maps and the reproducibility of the corticospinal tract. Diffusion tensor images and high-resolution T1-weighted images of 15 healthy volunteers were acquired; the DTI data were processed using DtiStudio and FSL software. The FA and color FA maps were compared with the sectional images of the Chinese visible human dataset. The probability maps of the corticospinal tract were generated as a quantitative measure of reproducibility for each voxel of the stereotaxic space. The fibers displayed by the diffusion tensor imaging were well consistent with the sectional images of the Chinese visible human dataset and the existing anatomical knowledge. The three-dimensional architecture of the white matter fibers could be clearly visualized on the diffusion tensor tractography. The diffusion tensor tractography can establish the 3D probability maps of the corticospinal tract, in which the degree of intersubject reproducibility of the corticospinal tract is consistent with the previous architectonic report. DTI is a reliable method of studying the fiber connectivity in human brain, but it is difficult to identify the tiny fibers. The probability maps are useful for evaluating and identifying the corticospinal tract in the DTI, providing anatomical information for the preoperative planning and improving the accuracy of surgical risk assessments preoperatively.

scholarly journals White matter plasticity in the corticospinal tract of musicians: A diffusion tensor imaging study

NeuroImage ◽  
2009 ◽  
Vol 46 (3) ◽  
pp. 600-607 ◽  
Author(s):  
Adrian Imfeld ◽  
Mathias S. Oechslin ◽  
Martin Meyer ◽  
Thomas Loenneker ◽  
Lutz Jancke
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Imaging Study ◽  
Diffusion Tensor Imaging Study

Migraine affects white-matter tract integrity: A diffusion-tensor imaging study

Cephalalgia ◽  
2015 ◽  
Vol 35 (13) ◽  
pp. 1162-1171 ◽  
Author(s):  
Catherine D Chong ◽  
Todd J Schwedt
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Imaging Study ◽  
White Matter Tract ◽  
Inferior Longitudinal Fasciculus ◽  
Left And Right ◽  
The Right

Background Specific white-matter tract alterations in migraine remain to be elucidated. Using diffusion tensor imaging (DTI), this study investigated whether the integrity of white-matter tracts that underlie regions of the “pain matrix” is altered in migraine and interrogated whether the number of years lived with migraine modifies fibertract structure. Methods Global probabilistic tractography was used to assess the anterior thalamic radiations, the corticospinal tracts and the inferior longitudinal fasciculi in 23 adults with migraine and 18 healthy controls. Results Migraine patients show greater mean diffusivity (MD) in the left and right anterior thalamic radiations, the left corticospinal tract, and the right inferior longitudinal fasciculus tract. Migraine patients also show greater radial diffusivity (RD) in the left anterior thalamic radiations, the left corticospinal tract as well as the left and right inferior longitudinal fasciculus tracts. No group fractional anisotropy (FA) differences were identified for any tracts. Migraineurs showed a positive correlation between years lived with migraine and MD in the right anterior thalamic radiations ( r = 0.517; p = 0.012) and the left corticospinal tract ( r = 0.468; p = 0.024). Conclusion Results indicate that white-matter integrity is altered in migraine and that longer migraine history is positively correlated with greater alterations in tract integrity.

scholarly journals DIFFUSION TENSOR TRACTOGRAPHY

Neurosurgery ◽  
2008 ◽  
Vol 63 (3) ◽  
pp. 452-459 ◽  
Author(s):  
Wai Hoe Ng ◽  
Dennis Lai-Hong Cheong ◽  
Kathleen Joy Khu ◽  
Govidasamy Venkatesh ◽  
Yee Kong Ng ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Magnetic Resonance ◽  
Fractional Anisotropy ◽  
Corticospinal Tract ◽  
Tumor Volume ◽  
Diffusion Tensor ◽  
Diffusion Tensor Tractography ◽  
Significant Difference ◽  
Fiber Number ◽  
And Diffusion

ABSTRACT OBJECTIVE Benign extracerebral lesions such as meningiomas may cause hemiparesis by compression and deviation without infiltrating the white matter. We used magnetic resonance diffusion tensor imaging and diffusion tensor tractography to investigate the effects of benign extracerebral lesions on the corticospinal tract (CST). METHODS Thirteen patients with extracerebral lesions (11 benign meningiomas and 2 benign cysts) underwent magnetic resonance diffusion tensor imaging and diffusion tensor tractography of the CST using fiber assignment by continuous tractography. The CST was reconstructed and assessed by comparing the ipsilateral and unaffected contralateral fibers. The tumor volume, relative fractional anisotropy, fiber deviation, relative fiber number, and relative fiber per voxel were compared between patients without and with temporary presurgical hemiparesis. RESULTS Seven patients without hemiparesis and five patients with temporary hemiparesis were analyzed; one patient had permanent weakness and was excluded from analysis. There was no significant difference in the tumor volume, relative fractional anisotropy, presence of cerebral edema, or CST deviation between groups. In patients with temporary hemiparesis, the median relative fiber number (mean, 0.35 ± 0.32) and relative fiber per voxel (mean, 0.49 ± 0.14) were significantly reduced compared with patients without hemiparesis (0.92 ± 0.55, P = 0.04; and 0.96 ± 0.28, P < 0.01, respectively). CONCLUSION In patients with benign extracerebral lesions, reduction in fiber number and fiber per voxel, but not fiber deviation, correlated with temporary hemiparesis. Clinical recovery was possible even if the CST fibers detected by diffusion tensor tractography were reduced by benign extracerebral lesions.

scholarly journals P.172 Diffusion MRI characteristics change in select cerebral white matter tracts after decompressive surgery for degenerative cervical myelopathy

2021 ◽  
Vol 48 (s3) ◽  
pp. S69-S69
Author(s):  
AC Friesen ◽  
SA Detombe ◽  
P Doyle-Pettypiece ◽  
H Haddad ◽  
W Ng ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corpus Callosum ◽  
Cervical Myelopathy ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Recovery Period ◽  
White Matter Tracts ◽  
Corticospinal Tracts ◽  
Degenerative Cervical Myelopathy

Background: Degenerative cervical myelopathy is characterized by progressive compression of the spinal cord resulting in debilitating loss of dexterity, independent ambulation, and sphincter control. Diffusion tensor imaging (DTI) has shown that, compared to healthy controls, myelopathy patients have decreased integrity of the corticospinal tracts and corpus callosum (Bernabeu-Sanz et al, 2020). Methods: Twenty-six myelopathy patients consented to cerebral diffusion tensor imaging (3 Tesla, 32 directions, b=1000) preoperatively, as well as 6-weeks, 12-weeks, and 6-months postoperatively. Average mean diffusivity (MD), fractional anisotropy (FA), radial diffusivity (RD), and axial diffusivity (AD) were measured in the corticospinal tracts, forceps major, and forceps minor. Results: Both MD and RD decreased from 6-12 weeks postoperatively in the right corticospinal tract. The forceps major of the corpus callosum showed an initial postoperative increase in MD followed by a subsequent increase in FA and decrease in RD 3-6 months postoperatively. The AD of the forceps major increased both immediately and 3-6 months postoperatively. Conclusions: Changes in microstructural integrity of the corticospinal tract and forceps major over the postoperative recovery period suggest a pattern of recovery in myelopathy patients. This study is the first to report postoperative DTI changes in myelopathy-relevant white matter tracts in the brain.

scholarly journals White Matter Integrity Involvement in Preclinical Stage of Familial Creutzfeldt-Jakob Disease: A Diffusion Tensor Imaging Study

2020 ◽  
Author(s):  
Donglai Jing ◽  
Yaojing Chen ◽  
Kexin Xie ◽  
Yue Cui ◽  
Chunlei Cui ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Corticospinal Tract ◽  
Diffusion Tensor ◽  
Healthy Controls ◽  
Superior Longitudinal Fasciculus ◽  
Preclinical Stage ◽  
Asymptomatic Carriers ◽  
Jakob Disease

Abstract Background : To explore the patterns of white matter (WM) alterations using diffusion tensor imaging (DTI) in the preclinical stage of familial Creutzfeldt-Jakob disease (fCJD) . Methods: 7 asymptomatic carriers of PRNP G114V mutation and 6 non-carriers from the same fCJD kindred were recruited at baseline. Follow-up was obtained in 7 asymptomatic carriers and 2 non-carriers 2 years later. We also included 10 symptomatic CJD patients and 10 age-and gender-matched healthy controls out of the kindred to observe the overlapping patterns of WM between asymptomatic carriers and symptomatic CJD patients. All subjects received clinical, neuropsychological assessments, electroencephalogram (EEG) tests, and DTI at baseline and follow-up. Tract-based spatial statistics (TBSS) was used in DTI study for whole-brain voxel wise analysis of fractional anisotropy (FA) and mean diffusivity (MD) in WM. Results were compared in three groups: baseline carriers against non-carriers (baseline analysis), changes after 2 years in carriers (follow-up analysis), and differences between symptomatic CJD patients and healthy controls (CJD patients analysis). Results: Neither the carriers nor the non-carriers develop any neurological symptoms during 2 years follow-up. Baseline analysis showed no group differences between carriers and non-carriers in MD and FA. Follow-up analysis showed significant increased MD in left inferior fronto-occipital fasciculus, left uncinate fasciculus, bilateral superior longitudinal fasciculus, and bilateral corticospinal tract (p < 0.05), among which increased MD in bilateral superior longitudinal fasciculus and right corticospinal tract overlaps the pattern of CJD patients. Conclusion: Integrity involvement within multiple WM tracts could be detected in preclinical stage of fCJD.

scholarly journals Oblique coronal view of the ACL double-bundle: Comparison of the Chinese Visible Human dataset and low-field MRI

2013 ◽  
Vol 6 (2) ◽  
pp. 606-610
Author(s):  
WEI CHEN ◽  
BING XIE ◽  
GUO-HONG ZU ◽  
GERIGK LARS ◽  
LI-WEN TAN ◽  
...  
Keyword(s):  
Double Bundle ◽  
Low Field ◽  
Chinese Visible Human ◽  
Low Field Mri ◽  
Coronal View ◽  
Human Dataset ◽  
Visible Human ◽  
Visible Human Dataset

scholarly journals The application of Chinese Visible Human dataset

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Shaoxiang Zhang ◽  
Bin Jie ◽  
Liwen Tan
Keyword(s):  
Chinese Visible Human ◽  
Human Dataset ◽  
Visible Human ◽  
Visible Human Dataset
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