scholarly journals Cancer Surgery in the Elderly

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Gopal C. Kowdley ◽  
Nishant Merchant ◽  
James P. Richardson ◽  
Justin Somerville ◽  
Myriam Gorospe ◽  
...  

The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly.

2018 ◽  
Vol 5 (6) ◽  
pp. 2000
Author(s):  
Omer Parlak ◽  
Fatma Dilek Dellal ◽  
Serap Ulusoy ◽  
Ibrahim Kılınc

Background: The aim of this study is to compare the results of patients who were treated with two groups (under 65 years and over 65 years) of thyroid cancer.Methods: A retrospective review of 1176 patients undergoing thyroid cancer surgery between January 2007 and December 2016 was performed. Patients were grouped as ≥65 (geriatric group) and <65 years (non-geriatric group).Results: A total of 139 patients (11.8%) were over 65 years of age and 1037 patients (88.2%) were under 65 years of age. There were 104 female (74.8%) and 35 (25.2%) male patients in the geriatric group. In the non-geriatric group, 917 (78%) patients were female and 259 (22%) were male (p = 0.39). FNAB showed a significant increase in malignant potential in the elderly (p = 0.005). In our series, malignant differences between geriatric and non-geriatric groups are less pronounced among thyroid carcinomas other than capsular invasion. Although there was no significant difference in histopathologic examination, malignant cytology was higher in the elderly patients. There was no significant difference between the young and elderly patients in terms of complication.Conclusions: In this study, papillary Thyroid Ca (PTC) was found to be the most common type of cancer and we could not find any difference in cancer type distribution in geriatric and non-geriatric patients. Total/near total thyroidectomy in experienced hands is safe for elderly patients. There is no difference in terms of complication.


2016 ◽  
Vol 28 (2) ◽  
pp. 241-251 ◽  
Author(s):  
Luciane Lena Pessanha Monteiro ◽  
Mark Douglas de Azevedo Jacyntho

The study addresses the use of the Semantic Web and Linked Data principles proposed by the World Wide Web Consortium for the development of Web application for semantic management of scanned documents. The main goal is to record scanned documents describing them in a way the machine is able to understand and process them, filtering content and assisting us in searching for such documents when a decision-making process is in course. To this end, machine-understandable metadata, created through the use of reference Linked Data ontologies, are associated to documents, creating a knowledge base. To further enrich the process, (semi)automatic mashup of these metadata with data from the new Web of Linked Data is carried out, considerably increasing the scope of the knowledge base and enabling to extract new data related to the content of stored documents from the Web and combine them, without the user making any effort or perceiving the complexity of the whole process.


2008 ◽  
Vol 195 (3) ◽  
pp. 344-348 ◽  
Author(s):  
Evan S. Ong ◽  
Mohamed Alassas ◽  
Kelli Bullard Dunn ◽  
Ashwani Rajput

2007 ◽  
Vol 392 (5) ◽  
pp. 549-558 ◽  
Author(s):  
Tsukasa Hotta ◽  
Katsunari Takifuji ◽  
Shozo Yokoyama ◽  
Kenji Matsuda ◽  
Takashi Higashiguchi ◽  
...  

Author(s):  
Daniel Soto Forero ◽  
Yony F. Ceballos ◽  
German Sànchez Torres

This paper describes a model to simulate the decision-making process of consumers that adopts technology within a dynamic social network. The proposed model use theories and tools from the psychology of consumer behavior, social networks and complex dynamical systems like the Consumat framework and fuzzy logic. The model has been adjusted using real data, tested with the automobile market and it can recreate trends like those described in the world market.


BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Gilles Manceau ◽  
Antoine Brouquet ◽  
Pascal Chaibi ◽  
Guillaume Passot ◽  
Olivier Bouché ◽  
...  

Abstract Background Several multicenter randomized controlled trials comparing laparoscopy and conventional open surgery for colon cancer have demonstrated that laparoscopic approach achieved the same oncological results while improving significantly early postoperative outcomes. These trials included few elderly patients, with a median age not exceeding 71 years. However, colon cancer is a disease of the elderly. More than 65% of patients operated on for colon cancer belong to this age group, and this proportion may become more pronounced in the coming years. In current practice, laparoscopy is underused in this population. Methods The CELL (Colectomy for cancer in the Elderly by Laparoscopy or Laparotomy) trial is a multicenter, open-label randomized, 2-arm phase III superiority trial. Patients aged 75 years or older with uncomplicated colonic adenocarcinoma or endoscopically unresectable colonic polyp will be randomized to either colectomy by laparoscopy or laparotomy. The primary endpoint of the study is overall postoperative morbidity, defined as any complication classification occurring up to 30 days after surgery. The secondary endpoints are: 30-day and 90-day postoperative mortality, 30-day readmission rate, quality of surgical resection, health-related quality of life and evolution of geriatric assessment. A 35 to 20% overall postoperative morbidity rate reduction is expected for patients operated on by laparoscopy compared with those who underwent surgery by laparotomy. With a two-sided α risk of 5% and a power of 80% (β = 0.20), 276 patients will be required in total. Discussion To date, no dedicated randomized controlled trial has been conducted to evaluate morbidity after colon cancer surgery by laparoscopy or laparotomy in the elderly and the benefits of laparoscopy is still debated in this context. Thus, a prospective multicenter randomized trial evaluating postoperative outcomes specifically in elderly patients operated on for colon cancer by laparoscopy or laparotomy with curative intent is warranted. If significant, such a study might change the current surgical practices and allow a significant improvement in the surgical management of this population, which will be the vast majority of patients treated for colon cancer in the coming years. Trial registration ClinicalTrials.gov NCT03033719 (January 27, 2017).


BMC Surgery ◽  
2013 ◽  
Vol 13 (Suppl 1) ◽  
pp. A44
Author(s):  
M Saracco ◽  
A Esposito ◽  
DG Palmieri ◽  
N Carlomagno ◽  
A Renda

Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 852
Author(s):  
Jaime A. Rincon ◽  
Angelo Costa ◽  
Paulo Novais ◽  
Vicente Julian ◽  
Carlos Carrascosa

Recent studies show that the elderly population has increased considerably in European society in recent years. This fact has led the European Union and many countries to propose new policies for caring services directed to this group. The current trend is to promote the care of the elderly in their own homes, thus avoiding inverting resources on residences. With this in mind, there are now new solutions in this direction, which try to make use of the continuous advances in computer science. This paper tries to advance in this area by proposing the use of a personal assistant to help older people at home while carrying out their daily activities. The proposed personal assistant is called ME3CA, and can be described as a cognitive assistant that offers users a personalised exercise plan for their rehabilitation. The system consists of a sensorisation platform along with decision-making algorithms paired with emotion detection models. ME3CA detects the users’ emotions, which are used in the decision-making process allowing for more precise suggestions and an accurate (and unbiased) knowledge about the users’ opinion towards each exercise.


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