scholarly journals Allograft Cellular Bone Matrix in Extreme Lateral Interbody Fusion: Preliminary Radiographic and Clinical Outcomes

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Antoine G. Tohmeh ◽  
Blake Watson ◽  
Mirna Tohmeh ◽  
Xavier J. Zielinski

Introduction. Extreme lateral interbody fusion (XLIF) is a minimally disruptive alternative for anterior lumbar interbody fusion. Recently, synthetic and allograft materials have been increasingly used to eliminate donor-site pain and complications secondary to autogenous bone graft harvesting. The clinical use of allograft cellular bone graft has potential advantages over autograft by eliminating the need to harvest autograft while mimicking autograft's biologic function. The objective of this study was to examine 12-month radiographic and clinical outcomes in patients who underwent XLIF with Osteocel Plus, one such allograft cellular bone matrix.Methods. Forty (40) patients were treated at 61 levels with XLIF and Osteocel Plus and included in the analysis.Results. No complications were observed. From preoperative to 12-month postoperative followup, ODI improved 41%, LBP improved 55%, leg pain improved 43.3%, and QOL (SF-36) improved 56%. At 12 months, 92% reported being “very” or “somewhat” satisfied with their outcome and 86% being either “very” or “somewhat likely” to choose to undergo the procedure again. Complete fusion was observed in 90.2% (55/61) of XLIF levels.Conclusions. Complete interbody fusion with Osteocel Plus was shown in 90.2% of XLIF levels, with the remaining 9.8% being partially consolidated and progressing towards fusion at 12 months.

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Adam M. Caputo ◽  
Keith W. Michael ◽  
Todd M. Chapman ◽  
Gene M. Massey ◽  
Cameron R. Howes ◽  
...  

Introduction. The use of extreme lateral interbody fusion (XLIF) and other lateral access surgery is rapidly increasing in popularity. However, limited data is available regarding its use in scoliosis surgery. The objective of this study was to evaluate the clinical outcomes of adults with degenerative lumbar scoliosis treated with XLIF.Methods. Thirty consecutive patients with adult degenerative scoliosis treated by a single surgeon at a major academic institution were followed for an average of 14.3 months. Interbody fusion was completed using the XLIF technique with supplemental posterior instrumentation. Validated clinical outcome scores were obtained on patients preoperatively and at most recent follow-up. Complications were recorded.Results. The study group demonstrated improvement in multiple clinical outcome scores. Oswestry Disability Index scores improved from 24.8 to 19.0 (P < 0.001). Short Form-12 scores improved, although the change was not significant. Visual analog scores for back pain decreased from 6.8 to 4.6 (P < 0.001) while scores for leg pain decreased from 5.4 to 2.8 (P < 0.001). A total of six minor complications (20%) were recorded, and two patients (6.7%) required additional surgery.Conclusions. Based on the significant improvement in validated clinical outcome scores, XLIF is effective in the treatment of adult degenerative scoliosis.


Medicine ◽  
2019 ◽  
Vol 98 (44) ◽  
pp. e17685 ◽  
Author(s):  
Yuan Gao ◽  
Jiaqi Li ◽  
Hao Cui ◽  
Fei Zhang ◽  
Yapeng Sun ◽  
...  

2014 ◽  
Vol 20 (6) ◽  
pp. 623-635 ◽  
Author(s):  
Marjan Alimi ◽  
Christoph P. Hofstetter ◽  
Guang-Ting Cong ◽  
Apostolos John Tsiouris ◽  
Andrew R. James ◽  
...  

Object Extreme lateral interbody fusion (ELIF) is a popular technique for anterior fixation of the thoracolumbar spine. Clinical and radiological outcome studies are required to assess safety and efficacy. The aim of this study was to describe the functional and radiological impact of ELIF in a degenerative disc disease population with a longer follow-up and to assess the durability of this procedure. Methods Demographic and perioperative data for all patients who had undergone ELIF for degenerative lumbar disorders between 2007 and 2011 were collected. Trauma and tumor cases were excluded. For radiological outcome, the preoperative, immediate postoperative, and latest follow-up coronal Cobb angle, lumbar sagittal lordosis, bilateral foraminal heights, and disc heights were measured. Pelvic incidence (PI) and PI–lumbar lordosis (PI-LL) mismatch were assessed in scoliotic patients. Clinical outcome was evaluated using the Oswestry Disability Index (ODI) and visual analog scale (VAS), as well as the Macnab criteria. Results One hundred forty-five vertebral levels were surgically treated in 90 patients. Pedicle screw and rod constructs and lateral plates were used to stabilize fixation in 77% and 13% of cases, respectively. Ten percent of cases involved stand-alone cages. At an average radiological follow-up of 12.6 months, the coronal Cobb angle was 10.6° compared with 23.8° preoperatively (p < 0.0001). Lumbar sagittal lordosis increased by 5.3° postoperatively (p < 0.0001) and by 2.9° at the latest follow-up (p = 0.014). Foraminal height and disc height increased by 4 mm (p < 0.0001) and 3.3 mm (p < 0.0001), respectively, immediately after surgery and remained significantly improved at the last follow-up. Separate evaluation of scoliotic patients showed no statistically significant improvement in PI and PI-LL mismatch either immediately postoperatively or at the latest follow-up. Clinical evaluation at an average follow-up of 17.6 months revealed an improvement in the ODI and the VAS scores for back, buttock, and leg pain by 21.1% and 3.7, 3.6, and 3.7 points, respectively (p < 0.0001). According to the Macnab criteria, 84.8% of patients had an excellent, good, or fair functional outcome. New postoperative thigh numbness and weakness was detected in 4.4% and 2.2% of the patients, respectively, which resolved within the first 3 months after surgery in all but 1 case. Conclusions This study provides what is to the authors' knowledge the most comprehensive set of radiological and clinical outcomes of ELIF in a fairly large population at a midterm follow-up. Extreme lateral interbody fusion showed good clinical outcomes with a low complication rate. The procedure allows for at least midterm clinically effective restoration of disc and foraminal heights. Improvement in coronal deformity and a small but significant increase in sagittal lordosis were observed. Nonetheless, no significant improvement in the PI-LL mismatch was achieved in scoliotic patients.


2021 ◽  
Vol 78 ◽  
pp. 130-132
Author(s):  
Masakazu Wakabayashi ◽  
Yurika Miyazaki ◽  
Kana Aoki ◽  
Hayato Yoshida ◽  
Kou Minoshima ◽  
...  

2017 ◽  
Vol 103 ◽  
pp. 869-875.e3 ◽  
Author(s):  
Claudio Schonauer ◽  
Martin Nikolaus Stienen ◽  
Oliver Pascal Gautschi ◽  
Karl Schaller ◽  
Enrico Tessitore

2014 ◽  
Vol 4 (1_suppl) ◽  
pp. s-0034-1376735-s-0034-1376735
Author(s):  
R. Hartl ◽  
F. Christensen ◽  
A. Korge ◽  
K. Lam ◽  
E. Vialle ◽  
...  

2021 ◽  
Vol 104 (6) ◽  
pp. 1027-1032

Background: Extreme Lateral Interbody Fusion (XLIF®) is a well-known transpsoas approach technique that confers advantages including excellent visualization, easy access to the lumbar disc, accommodation for a large anterior graft, restoration of disk height and lumbar alignment, and indirect decompression. However, no study in Thailand has investigated early postoperative complications after spinal fusion with XLIF surgery. Objective: To determine the early postoperative complication rates among Thai patients that underwent spinal fusion with XLIF procedure. Materials and Methods: The present study was a retrospective chart review to evaluate perioperative and early postoperative complications in patients that underwent spinal interbody fusion with XLIF procedure and were followed-up for a minimum of three months at the Department of Orthopedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand between 2015 and 2019. Results: One hundred eighteen patients, including 82 females and 36 males, with a mean age of 64.2 years and 165 levels, that were operated upon, were included. Eighty patients (67.8%) underwent one-level fusion, 29 (24.6%) had two-level fusion, and 9 (7.6%) underwent three-level fusion. Immediate postoperative complications occurred in 66 patients (55.9%), consisting of eight (6.7%) with medical complications, 57 (48.3%) with surgical complications, and one (0.8%) with combined medical and surgical complications. Postoperative complications were resolved within three months after surgery in 48 patients. Forty-one patients (34.7%) had postoperative proximal lower limb neuropathy. Only 10 patients (24.4%) still had neuropathy at the 3-month follow-up, but it did not affect their function. Conclusion: Postoperative proximal limb neuropathy, including thigh numbness, pain, or hip flexor weakness, had a high prevalence in the present study despite intraoperative neurophysiologic monitoring; however, most cases resolved by the 3-month follow-up. Patient education about potential nerve irritation complication is recommended, and meticulous preoperative radiographic assessment and careful step-by-step intraoperative surgical approach may reduce the rates of these postoperative complications. Keywords: Extreme lateral interbody fusion; Complications; Neuropathy; Postoperative


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