Aspects of chemical shift imaging which illustrate the cross-fertilization of methods and techniques in in vivo NMR imaging and spectroscopy

We discuss the methods of chemical shift imaging, or distributed NMR spectroscopy using techniques derived from NMR imaging. We point out that the problems, and artefacts, of most localized spectroscopy are substantially those of imaging, and that lessons learnt from the latter, and strategies developed for it, can be used to improve the quality of spectral data in many ways. Perhaps just as important now are the techniques used in spectroscopy which are being imported into imaging to provide additional contrast mechanisms, and, hopefully, data about tissue which cannot be obtained using other methods.