scholarly journals Thermally induced deterioration behaviour of two dolomitic marbles under heating–cooling cycles

2018 ◽  
Vol 5 (10) ◽  
pp. 180779 ◽  
Author(s):  
Zhong-jian Zhang ◽  
Jian-bin Liu ◽  
Biao Li ◽  
Xi-guang Yang
Keyword(s):  
Weight Loss ◽  
Compressive Strength ◽  
Uniaxial Compressive Strength ◽  
Three Dimensional ◽  
Elastic Wave Velocity ◽  
Experimental Investigations ◽  
Seasonal Temperature ◽  
Beijing City ◽  
Dolomitic Marble ◽  
Thermally Induced

Thermally induced deterioration behaviour can cause severe weathering in marbles. Most previous studies focus on the deterioration behaviour of calcitic marbles. Relevant studies of dolomitic marbles are generally carried out under a ‘high temperature and low cycling times' condition. Little attention is focused on the deterioration behaviour in dolomitic marbles when they are subjected to a large quantity of heating–cooling cycles under a ‘low temperature and high cycling times’ condition. This paper presents experimental investigations on the thermally induced deterioration behaviour of two Beijing dolomitic marbles (Qingbaishi Marble (QM) and Hanbaiyu Marble (HM)) under heating–cooling cycles up to 1000 cycling times. The applied temperature range is from –20°C to 60°C which is to simulate the seasonal temperature variations in Beijing city, China. Related properties such as weight loss, three-dimensional microtopography, elastic wave velocity and uniaxial compressive strength were measured at certain cycles. The results indicate that thermally induced deterioration behaviour will result in a continuous weight loss in dolomitic marble samples. Mechanical properties of those two marbles are strongly affected by heating and cooling treatments, which were reflected by the reductions of dynamic Young's modulus and uniaxial compressive strength with an increase of thermal cycles. Compared with QM, HM displays a higher level of thermally induced deterioration which should be due to the abundance of quartz mineral.

scholarly journals Numerical Investigation on the Evolution of Mechanical Properties of Rock Affected by Micro-Parameters

2020 ◽  
Vol 10 (14) ◽  
pp. 4957
Author(s):  
Haoyu Rong ◽  
Guichen Li ◽  
Dongxu Liang ◽  
Changlun Sun ◽  
Suhui Zhang ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Uniaxial Compressive Strength ◽  
Stress Ratio ◽  
Three Dimensional ◽  
Particle Flow Code ◽  
Parameter Calibration ◽  
Failure Characteristics ◽  
Failure Patterns ◽  
Response Characteristics ◽  
Bond Model

Investigating the micro-parameters of rock is vital for understanding the macro-properties of rock, such as the uniaxial compressive strength (UCS), Young’s modulus, failure patterns, etc. In this paper, based on the experimental results of rock material, a parallel-bond model in three-dimensional particle flow code (PFC3D) was applied to investigate the effects of the joint action of bond stiffness ratio and bond stress ratio on macro-properties of rock. The uniaxial compressive strength, stress–strain relationships, and failure characteristics, as well as underlying compression and failure mechanisms, in the process of parameter calibration, were systematically studied. The results indicated that the interaction of several micro-parameters would obviously change the response characteristics of the macro-properties of the model. The mechanism of the effects of various micro-parameters on the macro-properties of the model was further revealed. The change of the micro-parameters would change the strength and stress state of the bond between particles. The research results could promote the understanding of the failure mechanism of rock and improve the efficiency of micro-parameter calibration and the accuracy of calibration results.

scholarly journals Mechanical Behavior of Hydroxyapatite-Chitosan Composite: Effect of Processing Parameters

Minerals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 213
Author(s):  
Hamid Ait Said ◽  
Hassan Noukrati ◽  
Hicham Ben Youcef ◽  
Ayoub Bayoussef ◽  
Hassane Oudadesse ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Compressive Strength ◽  
Mechanical Strength ◽  
Bone Repair ◽  
Mechanical Stability ◽  
Three Dimensional ◽  
Processing Parameters ◽  
Composite Effect ◽  
Solid Liquid ◽  
The Impact

Three-dimensional hydroxyapatite-chitosan (HA-CS) composites were formulated via solid-liquid technic and freeze-drying. The prepared composites had an apatitic nature, which was demonstrated by X-ray diffraction and Infrared spectroscopy analyses. The impact of the solid/liquid (S/L) ratio and the content and the molecular weight of the polymer on the composite mechanical strength was investigated. An increase in the S/L ratio from 0.5 to 1 resulted in an increase in the compressive strength for HA-CSL (CS low molecular weight: CSL) from 0.08 ± 0.02 to 1.95 ± 0.39 MPa and from 0.3 ± 0.06 to 2.40 ± 0.51 MPa for the HA-CSM (CS medium molecular weight: CSM). Moreover, the increase in the amount (1 to 5 wt%) and the molecular weight of the polymer increased the mechanical strength of the composite. The highest compressive strength value (up to 2.40 ± 0.51 MPa) was obtained for HA-CSM (5 wt% of CS) formulated at an S/L of 1. The dissolution tests of the HA-CS composites confirmed their cohesion and mechanical stability in an aqueous solution. Both polymer and apatite are assumed to work together, giving the synergism needed to make effective cylindrical composites, and could serve as a promising candidate for bone repair in the orthopedic field.

scholarly journals Experimental Analysis of the Mechanical Properties and Resistivity of Tectonic Coal Samples with Different Particle Sizes

Energies ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 2303
Author(s):  
Congyu Zhong ◽  
Liwen Cao ◽  
Jishi Geng ◽  
Zhihao Jiang ◽  
Shuai Zhang
Keyword(s):  
Mechanical Properties ◽  
Particle Size ◽  
Compressive Strength ◽  
Elastic Modulus ◽  
Uniaxial Compressive Strength ◽  
Coalbed Methane ◽  
Coal Sample ◽  
Fine Particles ◽  
Particle Sizes ◽  
Tectonic Coal

Because of its weak cementation and abundant pores and cracks, it is difficult to obtain suitable samples of tectonic coal to test its mechanical properties. Therefore, the research and development of coalbed methane drilling and mining technology are restricted. In this study, tectonic coal samples are remodeled with different particle sizes to test the mechanical parameters and loading resistivity. The research results show that the particle size and gradation of tectonic coal significantly impact its uniaxial compressive strength and elastic modulus and affect changes in resistivity. As the converted particle size increases, the uniaxial compressive strength and elastic modulus decrease first and then tend to remain unchanged. The strength of the single-particle gradation coal sample decreases from 0.867 to 0.433 MPa and the elastic modulus decreases from 59.28 to 41.63 MPa with increasing particle size. The change in resistivity of the coal sample increases with increasing particle size, and the degree of resistivity variation decreases during the coal sample failure stage. In composite-particle gradation, the proportion of fine particles in the tectonic coal sample increases from 33% to 80%. Its strength and elastic modulus increase from 0.996 to 1.31 MPa and 83.96 to 125.4 MPa, respectively, and the resistivity change degree decreases. The proportion of medium particles or coarse particles increases, and the sample strength, elastic modulus, and resistivity changes all decrease.

scholarly journals Structural Characterization of Receptor–Receptor Interactions in the Allosteric Modulation of G Protein-Coupled Receptor (GPCR) Dimers

2021 ◽  
Vol 22 (6) ◽  
pp. 3241
Author(s):  
Raudah Lazim ◽  
Donghyuk Suh ◽  
Jai Woo Lee ◽  
Thi Ngoc Lan Vu ◽  
Sanghee Yoon ◽  
...  
Keyword(s):  
G Protein ◽  
Protein Interactions ◽  
Metabotropic Glutamate Receptor ◽  
Three Dimensional ◽  
Allosteric Modulation ◽  
Experimental Investigations ◽  
G Protein Coupled Receptor ◽  
Metabotropic Glutamate ◽  
Gpcr Activation ◽  
G Protein Coupled

G protein-coupled receptor (GPCR) oligomerization, while contentious, continues to attract the attention of researchers. Numerous experimental investigations have validated the presence of GPCR dimers, and the relevance of dimerization in the effectuation of physiological functions intensifies the attractiveness of this concept as a potential therapeutic target. GPCRs, as a single entity, have been the main source of scrutiny for drug design objectives for multiple diseases such as cancer, inflammation, cardiac, and respiratory diseases. The existence of dimers broadens the research scope of GPCR functions, revealing new signaling pathways that can be targeted for disease pathogenesis that have not previously been reported when GPCRs were only viewed in their monomeric form. This review will highlight several aspects of GPCR dimerization, which include a summary of the structural elucidation of the allosteric modulation of class C GPCR activation offered through recent solutions to the three-dimensional, full-length structures of metabotropic glutamate receptor and γ-aminobutyric acid B receptor as well as the role of dimerization in the modification of GPCR function and allostery. With the growing influence of computational methods in the study of GPCRs, we will also be reviewing recent computational tools that have been utilized to map protein–protein interactions (PPI).

scholarly journals Chitosan/Gelatin/PVA Scaffolds for Beta Pancreatic Cell Culture

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2372
Author(s):  
Yesenia Sánchez-Cardona ◽  
Claudia E. Echeverri-Cuartas ◽  
Marta E. Londoño López ◽  
Natalia Moreno-Castellanos
Keyword(s):  
Compressive Strength ◽  
Cell Viability ◽  
Pore Size ◽  
Three Dimensional ◽  
Ternary Blend ◽  
Ternary Blends ◽  
Binary Blend ◽  
Pancreatic Cell ◽  
Degradation Rates ◽  
Swelling Rate

Chitosan scaffolds based on blending polymers are a common strategy used in tissue engineering. The objective of this study was evaluation the properties of scaffolds based on a ternary blend of chitosan (Chi), gelatin (Ge), and polyvinyl alcohol (PVA) (Chi/Ge/PVA), which were prepared by cycles of freeze-thawing and freeze-drying. It then was used for three-dimensional BRIN-BD11 beta-cells culturing. Weight ratios of Chi/Ge/PVA (1:1:1, 2:2:1, 2:3:1, and 3:2:1) were proposed and porosity, pore size, degradation, swelling rate, compressive strength, and cell viability analyzed. All ternary blend scaffolds structures are highly porous (with a porosity higher than 80%) and interconnected. The pore size distribution varied from 0.6 to 265 μm. Ternary blends scaffolds had controllable degradation rates compared to binary blend scaffolds, and an improved swelling capacity of the samples with increasing chitosan concentration was found. An increase in Young’s modulus and compressive strength was observed with increasing gelatin concentration. The highest compressive strength reached 101.6 Pa. The MTT assay showed that the ternary blends scaffolds P3 and P4 supported cell viability better than the binary blend scaffold. Therefore, these results illustrated that ternary blends scaffolds P3 and P4 could provide a better environment for BRIN-BD11 cell proliferation.

scholarly journals Determination of Mechanical Properties of Altered Dacite by Laboratory Methods

Minerals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 813
Author(s):  
Veljko Rupar ◽  
Vladimir Čebašek ◽  
Vladimir Milisavljević ◽  
Dejan Stevanović ◽  
Nikola Živanović
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Rock Mass ◽  
Uniaxial Compressive Strength ◽  
Rock Material ◽  
Strength Parameter ◽  
Gradual Transition ◽  
Strength Parameters ◽  
Triaxial Compressive Strength ◽  
Heterogeneous Rock

This paper presents a methodology for determining the uniaxial and triaxial compressive strength of heterogeneous material composed of dacite (D) and altered dacite (AD). A zone of gradual transition from altered dacite to dacite was observed in the rock mass. The mechanical properties of the rock material in that zone were determined by laboratory tests of composite samples that consisted of rock material discs. However, the functional dependence on the strength parameter alteration of the rock material (UCS, intact UCS of the rock material, and mi) with an increase in the participation of “weaker” rock material was determined based on the test results of uniaxial and triaxial compressive strength. The participation of altered dacite directly affects the mode and mechanism of failure during testing. Uniaxial compressive strength (σciUCS) and intact uniaxial compressive strength (σciTX) decrease exponentially with increased AD volumetric participation. The critical ratio at which the uniaxial compressive strength of the composite sample equals the strength of the uniform AD sample was at a percentage of 30% AD. Comparison of the obtained exponential equation with practical suggestions shows a good correspondence. The suggested methodology for determining heterogeneous rock mass strength parameters allows us to determine the influence of rock material heterogeneity on the values σciUCS, σciTX, and constant mi. Obtained σciTX and constant mi dependences define more reliable rock material strength parameter values, which can be used, along with rock mass classification systems, as a basis for assessing rock mass parameters. Therefore, it is possible to predict the strength parameters of the heterogeneous rock mass at the transition of hard (D) and weak rock (AD) based on all calculated strength parameters for different participation of AD.

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