scholarly journals The contribution of glycosaminoglycans to the mechanical behaviour of the posterior human sclera

2016 ◽  
Vol 13 (119) ◽  
pp. 20160367 ◽  
Author(s):  
Barbara J. Murienne ◽  
Michelle L. Chen ◽  
Harry A. Quigley ◽  
Thao D. Nguyen

We characterized the structural and mechanical changes after experimental digestion of sulfated glycosaminoglycans (s-GAGs) in the human posterior sclera, using ultrasound thickness measurements and an inflation test with three-dimensional digital image correlation (3D-DIC). Each scleral specimen was first incubated in a buffer solution to return to full hydration, inflation tested, treated in a buffer solution with chondroitinase ABC (ChABC), then inflation tested again. After each test series, the thickness of eight locations was measured. After enzymatic treatment, the average scleral thickness decreased by 13.3% ( p < 0.001) and there was a stiffer overall stress–strain response ( p < 0.05). The stress–strain response showed a statistically significant increase in the low-pressure stiffness, high-pressure stiffness and hysteresis. Thus, s-GAGs play a measurable role in the mechanical behaviour of the posterior human sclera.

Author(s):  
Samer Adeeb ◽  
Dave Horsley ◽  
Junhui Yan ◽  
Michael A. Sutton ◽  
Anthony P. Reynolds

An important design, construction and maintenance concern for pipelines is the integrity of flaws in the girth welds. Numerous fitness for purpose codes are available to assess weld flaws, many of which were calibrated with reference to wide plate test data. Often, wide plate tests are conducted on girth welded pipe in the as-received condition, i.e. without application of a pipeline coating. The area adjacent to the weld is thus subjected to a thermal cycle due to the heat generated from the welding process. In some pipe materials this thermal cycle might be sufficient to induce strain aging. It is not clear how the welding process changes the behaviour of the area next to the weld. The results of such wide plate experiments are very important in assessing the acceptable flaws in a girth weld under a strain-based design. Therefore, it was important to understand the extent of the aging, specifically the stress-strain behaviour on either side of the girth weld. This paper presents results of cross-weld tensile tests, which utilized a two-dimensional digital image correlation (DIC) technique to determine displacement, and thus infer strain. The local strains were mapped to global stress to obtain local constitutive properties every 12.5mm along the length of the specimen. The DIC test results were very consistent and were also similar to results obtained from standard circumferential tensile tests at corresponding locations. The strength of the specimens, as defined by the relative strength of their stress-strain curves, was found to be highest in the girth weld region, to drop in the HAZ, and then to reach a plateau in the base metal. It was also shown that strain localization in one of the HAZ regions was clearly visible during the loading process and the near-HAZ regions had a stress-strain response with a yield stress value higher than the base metal. This behaviour was observed at 12.5mm away from the girth-weld centerline in both the transverse and longitudinal directions. The reason for this slight change of behaviour can be attributed to the effect of heating supplied to this part during welding (strain aging). The described DIC technique is very promising in obtaining local strain fields within very small areas of the tested specimens.


2021 ◽  
Author(s):  
William Siefert ◽  
James Rule ◽  
Boian Alexandrov ◽  
Jorge Penso ◽  
Michael P. Buehner

2017 ◽  
Vol 8 (2) ◽  
pp. 337-347 ◽  
Author(s):  
Jorge Barrios-Muriel ◽  
Francisco Javier Alonso Sánchez ◽  
David Rodríguez Salgado ◽  
Francisco Romero-Sánchez

Abstract. Today there is continuous development of wearable devices in various fields such as sportswear, orthotics and personal gadgets, among others. The design of these devices involves the human body as a support environment. Based on this premise, the development of wearable devices requires an improved understanding of the skin strain field of the body segment during human motion. This paper presents a methodology based on a three dimensional digital image correlation (3D-DIC) system to measure the skin strain field and to estimate anatomical lines with minimum deformation as design criteria for the aforementioned wearable devices. The errors of displacement and strain measurement related to 3-D reconstruction and out-of-plane motion are investigated and the results are acceptable in the case of large deformation. This approach can be an effective tool to improve the design of wearable devices in the clinical orthopaedics and ergonomics fields, where comfort plays a key role in supporting the rehabilitation process.


2021 ◽  
Vol 263 (3) ◽  
pp. 3861-3870
Author(s):  
Kenji Homma ◽  
Paul R. Braunwart ◽  
Patrick L. Clavette

Digital Image Correlation (DIC) is an image-based method for measuring displacement and/or stain on the surface of a structure. When coupled with a stereo pair of highspeed cameras, DIC can also capture three-dimensional dynamic deformation of a structure under vibratory loading. However, high frequency and small amplitude displacement typically associated with structural vibrations mean that extra care is required during measurement and data processing. It becomes more challenging when thermal disturbances are present in the optical path, for example from a heated air flow, which introduces extraneous noise due to disturbances in the refractive index. In the present study, a simple composite plate was vibrated under a shaker excitation and stereo DIC measurements were performed. The obtained vibratory displacement results were compared against accelerometers and a laser Doppler vibrometer. Heated air flow was introduced in front of the plate to observe the effects of thermal disturbances on the DIC measurements. Although the contributions from the thermal disturbances were clearly visible in the DIC displacement data, it was shown that the vibratory deflections of the structure could still be extracted by post processing of the DIC data.


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