scholarly journals Alec Douglas Bangham. 10 November 1921 — 9 March 2010

2011 ◽  
Vol 57 ◽  
pp. 25-43 ◽  
Author(s):  
Sir Brian Heap ◽  
Gregory Gregoriadis

A first meeting with Alec Bangham would leave an impression of a larger-than-life scientist with a penetrating curiosity and formidable features characteristically portrayed in the dramatic portrait painted by his nephew, Humphrey Bangham, which currently hangs in one of the Royal Society’s rooms. Or, as Jeffrey Watkins (FRS) experienced on reaching the Institute of Animal Physiology at Babraham in September 1963, ‘at the moment of my arrival he was avidly peering down a microscope and excitedly proclaiming the wonders of myelin figures as viewed through crossed polaroids … [and that] they might prove useful as model systems for the study of structure and function in biological membranes. It was decided that I should work immediately along these lines.’ So what were the formative events that led to these first impressions? What had contributed to the formation of a scientist who became known worldwide as the father of liposomes, the inventor of Artificial Lung Expanding Compound (ALEC)—and someone who never stopped thinking about membranes, surfactant, anaesthetics, cricket, vegetables, family and friends?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jolanda Hermanns ◽  
Nico Ermler

Abstract In this paper we describe and evaluate a study on the use of concepts in organic chemistry while solving tasks that are designed after the concept of school-related content knowledge (SRCK). The study was designed as a mixed methods study and conducted at a German university for the content of “organic chemistry”. As the results of this study show, the students rate the tasks and the use of anchoring concepts as for example “bonds” or “structure and function” as relevant for their future profession as a chemistry teacher. They therefore propose that concepts should be an integral part of their university studies as they find it lacking at the moment. Concepts can also be seen as an opportunity to build a bridge between school knowledge and university knowledge.


2021 ◽  
Vol XXXVII (1) ◽  
pp. 89-100
Author(s):  
Dorota Kondej

This paper presents basic information on a structure and function of biological membranes. Types of biomimetic membranes modelling properties of biological membranes were introduced. The method of testing surface properties of a lipid monolayer, which is the basic type of biomimetic membranes, was described. The presented method makes it possible to evaluate the effect of nanoparticles on the surface activity of biomimetic membranes based on the determination of the surface index MA. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.


1938 ◽  
Vol 59 (2) ◽  
pp. 267-307 ◽  
Author(s):  
Alastair Graham

During recent years there has been a very great advance in our knowledge of the minute structure and function of the various regions and glands of the alimentary canal of the prosobranch and pulmonate gastropods, without any corresponding increase in our understanding of the opisthobranch and, in particular, of the nudibranch gut. That the emphasis should be laid on the streptoneurous and the land-living forms is obviously due to their abundance and to the fact that they include almost all the familiar types of gastropod mollusc, but it is disappointing that, at the moment of writing, there exists only one account of the histology and function of the digestive system of either a dorid or an æolid—to confine attention to the two main types of nudibranch molluscs which occur in British waters—that of Millott (1937b). This is perhaps more noticeable when it is recalled that the nudibranchs have specialised along distinctly unusual lines, many of which are intimately associated with the food and feeding habits which the animals have adopted. The æolids, it is true, have attracted a lively interest in connexion with their possession of nematocysts, but the majority of investigators have apparently been content to trace these into the cnidosacs without concerning themselves over the other constituents of the animal's food.


Science ◽  
2013 ◽  
Vol 341 (6147) ◽  
pp. 771-773 ◽  
Author(s):  
Matteo Cargnello ◽  
Vicky V. T. Doan-Nguyen ◽  
Thomas R. Gordon ◽  
Rosa E. Diaz ◽  
Eric A. Stach ◽  
...  

Interactions between ceria (CeO2) and supported metals greatly enhance rates for a number of important reactions. However, direct relationships between structure and function in these catalysts have been difficult to extract because the samples studied either were heterogeneous or were model systems dissimilar to working catalysts. We report rate measurements on samples in which the length of the ceria-metal interface was tailored by the use of monodisperse nickel, palladium, and platinum nanocrystals. We found that carbon monoxide oxidation in ceria-based catalysts is greatly enhanced at the ceria-metal interface sites for a range of group VIII metal catalysts, clarifying the pivotal role played by the support.


Genes ◽  
2019 ◽  
Vol 10 (11) ◽  
pp. 855 ◽  
Author(s):  
Buscaino

Human fungal pathogens, such as Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans, are a public health problem, causing millions of infections and killing almost half a million people annually. The ability of these pathogens to colonise almost every organ in the human body and cause life-threating infections relies on their capacity to adapt and thrive in diverse hostile host-niche environments. Stress-induced genome instability is a key adaptive strategy used by human fungal pathogens as it increases genetic diversity, thereby allowing selection of genotype(s) better adapted to a new environment. Heterochromatin represses gene expression and deleterious recombination and could play a key role in modulating genome stability in response to environmental changes. However, very little is known about heterochromatin structure and function in human fungal pathogens. In this review, I use our knowledge of heterochromatin structure and function in fungal model systems as a road map to review the role of heterochromatin in regulating genome plasticity in the most common human fungal pathogens: Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans.


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