Rehabilitation program for the quality of life for individuals on highly active antiretroviral therapy in KwaZulu-Natal, South Africa

2011 ◽  
Vol 34 (4) ◽  
pp. 360-365 ◽  
Author(s):  
Sonill S. Maharaj ◽  
Verusia Chetty
Keyword(s):  
Quality Of Life ◽  
South Africa ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Rehabilitation Program ◽  
Highly Active ◽  
Kwazulu Natal

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to Highly Active Antiretroviral Therapy 

2020 ◽  
Author(s):  
Michael Lahai ◽  
Peter Bai. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Strong Association ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Highly Active ◽  
Health Domains

Abstract Background: Poor compliance to highly active antiretroviral therapy (HAART) can result in the poor quality of life in children living with HIV/AIDS because of low plasma drug concentration and the possibility of drug resistance. This study evaluates the response of caregivers for determination of adherence and the four quality of life domains in children (aged 14 years and under) on HAART.Methods: We conducted a cross-sectional study of 188 children, each accompanied by their caregivers at Ola During Children's Hospital and Makeni Government Hospital between September and November 2016. Adherence to HAART and Quality of life was assessed using the WHO Quality of life summary questionnaire (WHOQOL-BREF). We obtained ethical approval from the Sierra Leone Ethics and Scientific Review Committee. Results: The study revealed 5.9% adherence amongst paediatric patients, and a strong association of adherent patients(p=0.019*) to the physical health domain (mean=64.61 SD=8.1).Caregiver HIV status showed a strong association with the physical (mean=58.3, SD=11.7 and p=0.024*), and psychological health domains (mean=68.2, SD=14.7 and p=0.001). Caregiver type (mother/father/sibling) accompanying child to hospital also showed strong associated with the physical (mean=58.0, SD=10.6, p <0.001), psychological (mean 68.2 SD=14.81 p <0.001) and environmental health domains (mean=59.7, SD=13.47, p <0.001). Further regression analysis showed a strong association with physical health domain for HIV positive caregivers (p=0.014) and adherent paediatric patients (p=0.005). Nuclear family also showed a strong association with psychological (p<0.001) and environmental (p=0.001) health domains. Conclusion: This study showed a strong association between the quality of life domains and the involvement of nuclear family caregiver, HIV-positive caregiver and adherence to HAART. Our study suggests that the involvement of any member of the nuclear family, HIV positive parents and patient adherence to therapy can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy in the two hospitals.

scholarly journals A cross-sectional study on caregivers’ perspective of the quality of life and adherence of paediatric HIV patients to highly active antiretroviral therapy

2019 ◽  
Author(s):  
Michael Lahai ◽  
Peter B. James ◽  
Noel N. Wannang ◽  
Haja R. Wurie ◽  
Sorie Conteh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Nuclear Family ◽  
Hiv Status ◽  
Cross Sectional ◽  
Paediatric Hiv ◽  
Highly Active ◽  
Hiv Aids

Abstract Background Non-compliance to highly active antiretroviral therapy (HAART) can lead to sub-therapeutic drug concentrations in children leading to emergence of drug resistance and poor quality of life in children with HIV/AIDS. This study assess the response of caregivers for determination of the percentage adherence, child and caregivers’ demographics and related characters to the four domains of quality of life in children (aged 14 years and under) on HAART. Methods A cross-sectional survey was done for 188 paediatric patients accompanied by their caregivers’ attending Ola During Children’s Hospital and Makeni Government Hospital between September and November 2016 in Sierra Leone with ethical approval obtained from the Sierra Leone Ethics and Scientific Review Committee; Directorate of Policy and Planning, Ministry of Health and Sanitation. Adherence to HAART was measured as no indication of a missed dose in the past week or month using three adherence questions on dose in the past week or month. Quality of life was assessed using the four domains of the Quality of life summary questionnaire (WHOQOL-BREF) as the dependent variable and the demographic characteristics of caregiver and child as the independent variable. Inferential test was used to determine the association between variables and the regression model to determine association of significant variables to the four domains of the WHOQOL BREF. Results The study showed 5.9% adherence among 188 paediatric HIV/AIDs patients. Caregiver HIV status and caregiver type were also found to be associated with quality of life domains with high mean values for HIV positive caregivers and caregiver type that included a member of the nuclear family (father, mother or siblings). Conclusion This study showed strong association for involvement of caregiver that includes the nuclear family, caregiver’s knowledge of their HIV status and adherence to HAART. Therefore, these factors can improve the quality of life of paediatric HIV/AIDS patients on highly active antiretroviral therapy.

Health-Related Quality of Life After 1 Year of Highly Active Antiretroviral Therapy

2003 ◽  
Vol 32 (1) ◽  
pp. 38-47 ◽  
Author(s):  
Patrizia Carrieri ◽  
Bruno Spire ◽  
Ségolène Duran ◽  
Christine Katlama ◽  
Dominique Peyramond ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Health Related Quality ◽  
Highly Active ◽  
Related Quality ◽  
Health Related
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