Control of spasticity in a multiple sclerosis model using central nervous system‐excluded CB 1 cannabinoid receptor agonists

2013 ◽  
Vol 28 (1) ◽  
pp. 117-130 ◽  
Author(s):  
Gareth Pryce ◽  
Cristina Visintin ◽  
Sreeram V. Ramagopalan ◽  
Sarah Al‐Izki ◽  
Lia E. De Faveri ◽  
...  
2017 ◽  
Vol 62 (1) ◽  
Author(s):  
Christine Søholm Hansen ◽  
Henrik Hasseldam ◽  
Idahella Hyldgaard Bacher ◽  
Stig Milan Thamsborg ◽  
Flemming Fryd Johansen ◽  
...  

AbstractMultiple sclerosis is a chronic inflammatory central nervous system (CNS) disease, which affects about 1 in 1000 individuals in the western world. It has been suggested that this relatively high prevalence is linked to a high level of hygiene,


2021 ◽  
Author(s):  
Bardia Nourbakhsh ◽  
Christian Cordano ◽  
Carlo Asteggiano ◽  
Klemens Ruprecht ◽  
Carolin Otto ◽  
...  

2017 ◽  
Vol 16 (03) ◽  
pp. 164-170
Author(s):  
Rachel Gottlieb-Smith ◽  
Amy Waldman

AbstractAcquired demyelinating syndromes (ADS) present with acute or subacute monofocal or polyfocal neurologic deficits localizing to the central nervous system. The clinical features of distinct ADS have been carefully characterized including optic neuritis, transverse myelitis, and acute disseminated encephalomyelitis. These disorders may all be monophasic disorders. Alternatively, optic neuritis, partial transverse myelitis, and acute disseminated encephalomyelitis may be first presentations of a relapsing or polyphasic neuroinflammatory disorder, such as multiple sclerosis or neuromyelitis optica. The clinical features of these disorders and the differential diagnosis are discussed in this article.


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