Inhibition of human hair follicle growth by endo‐and exocannabinoids

2007 ◽  
Vol 21 (13) ◽  
pp. 3534-3541 ◽  
Author(s):  
Andrea Telek ◽  
Tamás Bíró ◽  
Enikő Bodó ◽  
Balázs I. Tóth ◽  
Istvíin Borbíró ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hair Follicle Growth

Engineered extracellular vesicle mimetics from macrophage promotes hair growth in mice and promotes human hair follicle growth

2021 ◽  
pp. 112887
Author(s):  
Ramya Lakshmi Rajendran ◽  
Prakash Gangadaran ◽  
Mi Hee Kwack ◽  
Ji Min Oh ◽  
Chae Moon Hong ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Hair Growth ◽  
Extracellular Vesicle ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hair Follicle Growth

scholarly journals 102 EZH2 is required for human hair follicle growth and epidermal differentiation

2016 ◽  
Vol 136 (9) ◽  
pp. S178
Author(s):  
I. Asamaowei ◽  
N. Farjo ◽  
V. Botchkarev ◽  
N.V. Botchkareva ◽  
A.N. Mardaryev
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Epidermal Differentiation ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hair Follicle Growth

scholarly journals Platelet factor 4 inhibits human hair follicle growth and promotes androgen receptor expression in human dermal papilla cells

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9867
Author(s):  
Ke Sha ◽  
Mengting Chen ◽  
Fangfen Liu ◽  
San Xu ◽  
Ben Wang ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Hair Follicle ◽  
Human Hair ◽  
Hair Growth ◽  
Dermal Papilla ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Dermal Papilla Cells ◽  
Platelet Factor ◽  
Hair Follicle Growth

Platelet-rich plasma (PRP) has been reported recently as a potential therapeutic approach for alopecia, such as androgenetic alopecia, but the exact mechanisms and effects of specific components of this recipe remain largely unknown. In this study, we identified that platelet factor 4 (PF4), a component of PRP, significantly suppressed human hair follicle growth and restrained the proliferation of human dermal papilla cells (hDPCs). Furthermore, our results showed that PF4 upregulated androgen receptor (AR) in human dermal papilla cells in vitro and via hair follicle organ culture. Among the hair growth-promoting and DP-signature genes investigated, PF4 decreased the expression of Wnt5a, Wnt10b, LEF1, HEY1 and IGF-1, and increased DKK1 expression, but did not affect BMP2 and BMP4 expression. Collectively, Our data demonstrate that PF4 suppresses human hair follicle growth possibly via upregulating androgen receptor signaling and modulating hair growth-associated genes, which provides thought-provoking insights into the application and optimization of PRP in treating hair loss.

scholarly journals Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo

2018 ◽  
Vol 138 (6) ◽  
pp. 1420-1422 ◽  
Author(s):  
Iain S Haslam ◽  
Jonathan A Hardman ◽  
Ralf Paus
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Ex Vivo ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Hair Follicle Growth

CRH peptides modulate human hair follicle growth in vitro- a preliminary study

2008 ◽  
Vol 13 (9) ◽  
pp. 582-583
Author(s):  
S. Kauser ◽  
A. Slominski ◽  
E. T. Wei ◽  
D. J. Tobin
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Follicle Growth ◽  
Human Hair Follicle ◽  
Preliminary Study ◽  
Hair Follicle Growth
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