Prostaglandin H synthase‐catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration 1

2006 ◽  
Vol 20 (6) ◽  
pp. 638-650 ◽  
Author(s):  
Winnie Jeng ◽  
Annmarie Ramkissoon ◽  
Toufan Parman ◽  
Peter G. Wells
Keyword(s):  
Free Radical ◽  
Nerve Terminal ◽  
Dna Oxidation ◽  
Prostaglandin H Synthase ◽  
Radical Intermediates ◽  
Terminal Degeneration ◽  
Prostaglandin H

scholarly journals Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes

1989 ◽  
Vol 264 (14) ◽  
pp. 7936-7943
Author(s):  
J Schreiber ◽  
G L Foureman ◽  
M F Hughes ◽  
R P Mason ◽  
T E Eling
Keyword(s):  
Free Radical ◽  
Prostaglandin H Synthase ◽  
Prostaglandin H

Reduced DNA oxidation in aged prostaglandin H synthase-1 knockout mice

2011 ◽  
Vol 50 (4) ◽  
pp. 550-556 ◽  
Author(s):  
Winnie Jeng ◽  
Annmarie Ramkissoon ◽  
Peter G. Wells
Keyword(s):  
Knockout Mice ◽  
Dna Oxidation ◽  
Prostaglandin H Synthase ◽  
Prostaglandin H

Reaction and Free Radical Kinetics of Prostaglandin H Synthase with Manganese Protoporphyrin IX as the Prosthetic Group

Biochemistry ◽  
1994 ◽  
Vol 33 (18) ◽  
pp. 5428-5439 ◽  
Author(s):  
Richard J. Kulmacz ◽  
Graham Palmer ◽  
Chunhong Wei ◽  
Ah-Lim Tsai
Keyword(s):  
Free Radical ◽  
Protoporphyrin Ix ◽  
Prostaglandin H Synthase ◽  
Prosthetic Group ◽  
Prostaglandin H ◽  
Kinetics Of
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