scholarly journals Projected costs associated with school-based screening to inform deployment of Dengvaxia: Vietnam as a case study

2018 ◽  
Vol 112 (8) ◽  
pp. 369-377 ◽  
Author(s):  
Hugo C Turner ◽  
Bridget A Wills ◽  
Motiur Rahman ◽  
Hoang Quoc Cuong ◽  
Guy E Thwaites ◽  
...  
Keyword(s):  
Large Scale ◽  
World Health ◽  
Enzyme Linked Immunosorbent Assay ◽  
Future Cost ◽  
Dengue Vaccine ◽  
School Based ◽  
Operational Costs ◽  
Financial Costs ◽  
The World

Abstract Background After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization’s recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale individual dengue screening and/or dengue serosurveys have become an important consideration for decision making by policymakers in dengue-endemic areas. Methods We used an ingredients-based approach to estimate the financial costs for conducting both a school-based dengue serosurvey and school-based individual dengue screening within a typical province in Vietnam, using an existing commercial indirect immunoglobulin G enzyme-linked immunosorbent assay kit. This costing is hypothetical and based on estimates regarding the resources that would be required to perform such activities. Results We estimated that performing a school-based individual screening of 9-year-olds would cost US$9.25 per child tested or US$197,827 in total for a typical province. We also estimated that a school-based serosurvey would cost US$10,074, assuming one class from each of the grades that include 8- to 11-year-olds are sampled at each of the 12 selected schools across the province. Conclusions The study indicates that using this vaccine safely on a large-scale will incur noteworthy operational costs. It is crucial that these be considered in future cost-effectiveness analyses informing how and where the vaccine is deployed.

Converting to a Synchronous Virtual Nursing Research Conference Amidst a Pandemic: A Case Study

2021 ◽  
Vol 27 (2) ◽  
pp. 118-124
Author(s):  
Lilian J. Canamo ◽  
Jessica P. Bejar ◽  
Judy E. Davidson
Keyword(s):  
World Health Organization ◽  
Large Scale ◽  
University Of California ◽  
World Health ◽  
User Engagement ◽  
Research Conference ◽  
The World ◽  
Health Organization ◽  
The University

University of California San Diego Health was set to launch its 13th annual Nursing and Inquiry Innovation Conference event in June 2020. However, the Coronavirus Disease 2019 (COVID-19) pandemic placed a barrier to large gatherings throughout the world. Because the World Health Organization designated 2020 as the Year of the Nurse and Midwife, the University committed to continuing the large-scale conference, converting to a virtual event. This article reviews the methodologies behind the delivery of the virtual event and implications for user engagement and learning on the blended electronic platform.

scholarly journals DEWORMING DELUSIONS? MASS DRUG ADMINISTRATION IN EAST AFRICAN SCHOOLS

2016 ◽  
Vol 48 (S1) ◽  
pp. S116-S147 ◽  
Author(s):  
Tim Allen ◽  
Melissa Parker
Keyword(s):  
Drug Administration ◽  
Mass Drug Administration ◽  
Large Scale ◽  
Local Level ◽  
Field Research ◽  
World Health ◽  
Parasitic Infections ◽  
Curative Therapy ◽  
School Based ◽  
The World

SummaryRecent debates about deworming school-aged children in East Africa have been described as the ‘Worm Wars’. The stakes are high. Deworming has become one of the top priorities in the fight against infectious diseases. Staff at the World Health Organization, the Gates Foundation and the World Bank (among other institutions) have endorsed the approach, and school-based treatments are a key component of large-scale mass drug administration programmes. Drawing on field research in Uganda and Tanzania, and engaging with both biological and social evidence, this article shows that assertions about the effects of school-based deworming are over-optimistic. The results of a much-cited study on deworming Kenyan school children, which has been used to promote the intervention, are flawed, and a systematic review of randomized controlled trials demonstrates that deworming is unlikely to improve overall public health. Also, confusions arise by applying the term deworming to a variety of very different helminth infections and to different treatment regimes, while local-level research in schools reveals that drug coverage usually falls below target levels. In most places where data exist, infection levels remain disappointingly high. Without indefinite free deworming, any declines in endemicity are likely to be reversed. Moreover, there are social problems arising from mass drug administration that have generally been ignored. Notably, there are serious ethical and practical issues arising from the widespread practice of giving tablets to children without actively consulting parents. There is no doubt that curative therapy for children infected with debilitating parasitic infections is appropriate, but overly positive evaluations of indiscriminate deworming are counter-productive.

HIPEREMESIS GRAVIDARUM PADA IBU HAMIL DI KLINIK BIDAN SUPRIYATI SRIBIT BERBAH SLEMAN

2019 ◽  
Vol 14 (1) ◽  
pp. 51
Author(s):  
Pramukti Dian Setianingrum ◽  
Farah Irmania Tsani
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Unwanted Pregnancy ◽  
The Body ◽  
Nausea And Vomiting ◽  
Daily Activities ◽  
World Health ◽  
The World

Backgroud: The World Health Organization (WHO) explained that the number of Hyperemesis Gravidarum cases reached 12.5% of the total number of pregnancies in the world and the results of the Demographic Survey conducted in 2007, stated that 26% of women with live births experienced complications. The results of the observations conducted at the Midwife Supriyati Clinic found that pregnant women with hyperemesis gravidarum, with a comparison of 10 pregnant women who examined their contents there were about 4 pregnant women who complained of excessive nausea and vomiting. Objective: to determine the hyperemesis Gravidarum of pregnant mother in clinic. Methods: This study used Qualitative research methods by using a case study approach (Case Study.) Result: The description of excessive nausea of vomiting in women with Hipermemsis Gravidarum is continuous nausea and vomiting more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the body weight decreases and interferes with daily activities days The factors that influence the occurrence of Hyperemesis Gravidarum are Hormonal, Diet, Unwanted Pregnancy, and psychology, primigravida does not affect the occurrence of Hyperemesis Gravidarum. Conclusion: Mothers who experience Hyperemesis Gravidarum feel nausea vomiting continuously more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the weight decreases and interferes with daily activities, it is because there are several factors, namely, hormonal actors, diet, unwanted pregnancy, and psychology.

scholarly journals Economic burden of silent mental disorders: a case study of agnosia in schizophrenia

2017 ◽  
Vol 5 (1) ◽  
pp. 401
Author(s):  
Vijay Kumar Chattu ◽  
Paula Mahon
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Mental Health Problems ◽  
Action Plan ◽  
Developed Countries ◽  
World Health ◽  
Economic Output ◽  
The World

Mental health problems affect society as a whole, and not just a small, isolated segment. In developed countries with well-organized healthcare systems, between 44% and 70% of patients with mental disorders do not receive treatment whereas in developing countries the treatment gap being close to 90%. Schizophrenia is a severe mental disorder affecting more than 21 million people worldwide. People with schizophrenia are 2-2.5 times more likely to die early than the general population. The case study highlights about agnosia in a schizophrenic patient in a primary care setting and how to address the management at a broader perspective using the appropriate antipsychotic medication and ensuring the support from a family without violating the human rights of the patient. The World Economic Forum estimated that the cumulative global impact of mental disorders in terms of lost economic output will amount to US$ 16 trillion over the next 20 years, equivalent to more than 1% of the global gross domestic product. Mental health should be a concern for all of us, rather than only for those who suffer from a mental disorder. The mental health action plan 2013-2020, endorsed by the World Health Assembly in 2013, highlights the steps required to provide appropriate services for people with mental disorders including schizophrenia. A key recommendation of the action plan is to shift services from institutions to the community. Mental health must be considered a focus of renewed investment not just in terms of human development and dignity but also in terms of social and economic development.

Networks as systems

2018 ◽  
Vol 32 (1) ◽  
pp. 9-24 ◽  
Author(s):  
Allan Best ◽  
Alex Berland ◽  
Trisha Greenhalgh ◽  
Ivy L. Bourgeault ◽  
Jessie E. Saul ◽  
...  
Keyword(s):  
Network Theory ◽  
Large Scale ◽  
Human Resources For Health ◽  
Flexible Structures ◽  
Communication Strategy ◽  
Global Network ◽  
World Health ◽  
Content Type ◽  
Large Complex

Purpose The purpose of this paper is to present a case study of the World Health Organization’s Global Healthcare Workforce Alliance (GHWA). Based on a commissioned evaluation of GHWA, it applies network theory and key concepts from systems thinking to explore network emergence, effectiveness, and evolution to over a ten-year period. The research was designed to provide high-level strategic guidance for further evolution of global governance in human resources for health (HRH). Design/methodology/approach Methods included a review of published literature on HRH governance and current practice in the field and an in-depth case study whose main data sources were relevant GHWA background documents and key informant interviews with GHWA leaders, staff, and stakeholders. Sampling was purposive and at a senior level, focusing on board members, executive directors, funders, and academics. Data were analyzed thematically with reference to systems theory and Shiffman’s theory of network development. Findings Five key lessons emerged: effective management and leadership are critical; networks need to balance “tight” and “loose” approaches to their structure and processes; an active communication strategy is key to create and maintain support; the goals, priorities, and membership must be carefully focused; and the network needs to support shared measurement of progress on agreed-upon goals. Shiffman’s middle-range network theory is a useful tool when guided by the principles of complex systems that illuminate dynamic situations and shifting interests as global alliances evolve. Research limitations/implications This study was implemented at the end of the ten-year funding cycle. A more continuous evaluation throughout the term would have provided richer understanding of issues. Experience and perspectives at the country level were not assessed. Practical implications Design and management of large, complex networks requires ongoing attention to key issues like leadership, and flexible structures and processes to accommodate the dynamic reality of these networks. Originality/value This case study builds on growing interest in the role of networks to foster large-scale change. The particular value rests on the longitudinal perspective on the evolution of a large, complex global network, and the use of theory to guide understanding.

Exploiting Digital Skills in Higher Education

2021 ◽  
pp. 1-20
Author(s):  
Domitilla Magni ◽  
Beatrice Orlando ◽  
Manlio Del Giudice
Keyword(s):  
Higher Education ◽  
Large Scale ◽  
Digital Transformation ◽  
Strong Impact ◽  
Business And Society ◽  
Case Study Analysis ◽  
Benefit Corporation ◽  
The World ◽  
Digital Skills

Thus far, digital transformation had a strong impact on business and society. The large-scale adoption of digital technologies changed social relationships and opened up to new opportunities for higher education. Currently, the interplay between innovation and digitalization become are among the most important assets for the educational system. In this light, this chapter aims to explore how digital skills and competencies modify the issue of co-creation in higher education. The authors use the case study analysis to explore such theme. The Little Genius International case is presented and discussed: an international alternative school in English for digital natives recognized as the best benefit corporation for the world. The main contribution of the chapter is that it outlines what are the new digital skills and competencies enabling a better understanding of the concept of students' co-creation in HEIs.

A Comparative Analysis of Dam Safety Assurance Laws

2014 ◽  
Vol 1 (1) ◽  
pp. 29-57 ◽  
Author(s):  
John Dean Pisaniello
Keyword(s):  
Comparative Analysis ◽  
Large Scale ◽  
Safety Management ◽  
Dam Safety ◽  
Safety Issues ◽  
Safety Assurance ◽  
The World ◽  
The Individual ◽  
Privately Owned

A number of horrific failures of both public and privately owned dams in recent decades has triggered serious concern over the safety of dams throughout the world. However, in Australia, although much Government attention is being devoted to the medium- to large-scale dams, minimal attention is being paid to the serious potential cumulative, catchment-wide problems associated with smaller private dams. The paper determines how to consider addressing hazardous private dam safety issues generally through a comparative analysis of international dam safety policy/law systems. The analysis has identified elements of best and minimum practice that can and do exist successfully to provide deserved assurance to the community of the proper safety management of hazardous private dams at both the individual and cumulative, catchment-wide levels. These elements provide benchmarks that enable ‘appropriate’ legislative arrangements to be determined for different jurisdictional circumstances as illustrated with an Australian policy-deficient case study.

What Lies Beneath

2021 ◽  
pp. 76-94
Author(s):  
Briana Toole
Keyword(s):  
Large Scale ◽  
White Supremacy ◽  
Underlying Structure ◽  
The World ◽  
Epistemic Frame

Our ability to dismantle white supremacy is compromised by the fact that we do not fully appreciate what, precisely, white supremacy is. In this chapter, I suggest understanding white supremacy as an epistemological system—an epistemic frame that serves as the foundation for how we understand and interact with the world. The difficulty in dismantling an epistemological system lies in its resilience—a system’s capacity to resist change to its underlying structure while, at the same time, offering the appearance of large-scale reform. Using white supremacy as a case study, here I explore what features enable this resilience. An analysis of white supremacy that presents it as more than a tool of social and political oppression, but as an epistemic system that makes this oppression possible, allows us to better understand, and eventually overthrow, such systems.

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