scholarly journals Longitudinal Study of Prenatal and Postnatal Lead Exposure and Early Cognitive Development in Al-Kharj, Saudi Arabia: A Preliminary Results of Cord Blood Lead Levels

2008 ◽  
Vol 54 (5) ◽  
pp. 300-307 ◽  
Author(s):  
I. Al-Saleh ◽  
N. Shinwari ◽  
M. Nester ◽  
A. Mashhour ◽  
L. Moncari ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Longitudinal Study ◽  
Cognitive Development ◽  
Cord Blood ◽  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Preliminary Results ◽  
Lead Levels

scholarly journals Sex-Dependent Impact of Low-Level Lead Exposure during Prenatal Period on Child Psychomotor Functions

2018 ◽  
Vol 15 (10) ◽  
pp. 2263 ◽  
Author(s):  
Kinga Polanska ◽  
Wojciech Hanke ◽  
Natalia Pawlas ◽  
Ewelina Wesolowska ◽  
Agnieszka Jankowska ◽  
...  
Keyword(s):  
Cord Blood ◽  
Lead Exposure ◽  
Blood Lead ◽  
Psychomotor Development ◽  
Blood Lead Levels ◽  
Prenatal Period ◽  
Low Level ◽  
Child Neurodevelopment ◽  
Lead Levels ◽  
The Impact

The impact of exposure to lead on child neurodevelopment has been well established. However, sex differences in vulnerability are still not fully explained. We aimed at evaluating the effect of a low-level lead exposure, as measured between 20 to 24 weeks of pregnancy and in cord blood, on developmental scores up to 24 months of age in 402 children from the Polish Mother and Child Cohort (REPRO_PL). Additionally, sex-dependent susceptibility to lead at this very early stage of psychomotor development was assessed. The blood lead levels were analyzed using inductively coupled plasma mass spectrometry (ICP-MS). In order to estimate the children’s neurodevelopment, the Bayley Scales of Infant and Toddler Development was applied. The geometric mean (GM) for blood lead level during 20–24 weeks of pregnancy was 0.99 ± 0.15 µg/dL and, in the cord blood, it was 0.96 ± 0.16 µg/dL. There was no statistically significant impact of lead exposure during prenatal period on the girls’ psychomotor abilities. Among the boys, we observed lower scores for cognitive functions, along with increasing cord blood lead levels (β = −2.07; p = 0.04), whereas the results for the language and motor abilities were not statistically significant (p > 0.05). Our findings show that fetal exposure to very low lead levels might affect early cognitive domain, with boys being more susceptible than girls. Education on health, higher public awareness, as well as intervention programs, along with relevant regulations, are still needed to reduce risks for the vulnerable population subgroups.

scholarly journals Blood lead level and risk of hypertension in the United States National Health and Nutrition Examination Survey 1999–2016

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Man Fung Tsoi ◽  
Chris Wai Hang Lo ◽  
Tommy Tsang Cheung ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
The United States ◽  
Study Data ◽  
Blood Lead Levels ◽  
Environmental Lead ◽  
Lead Levels

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

Low-Level Lead Exposure and Blood Lead Levels in Children: A Cross-Sectional Survey

2001 ◽  
Vol 56 (6) ◽  
pp. 501-505 ◽  
Author(s):  
Aysha Habib Khan ◽  
Amanullah Khan ◽  
Farooq Ghani ◽  
Muhammad Khurshid
Keyword(s):  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Low Level ◽  
Lead Levels

scholarly journals Occupational Lead Exposure: Blood Lead Levels of Apprentices in Bursa, Turkey

2009 ◽  
Vol 47 (1) ◽  
pp. 97-102 ◽  
Author(s):  
Kayihan PALA ◽  
Alpaslan TURKKAN ◽  
Seref GUCER ◽  
Erdinc OSMAN ◽  
Hamdi AYTEKIN
Keyword(s):  
Lead Exposure ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Occupational Lead Exposure ◽  
Lead Levels

scholarly journals Prevalence of elevated blood lead levels among pregnant women and sources of lead exposure in rural Bangladesh: A case control study

2018 ◽  
Vol 166 ◽  
pp. 1-9 ◽  
Author(s):  
Jenna E. Forsyth ◽  
M. Saiful Islam ◽  
Sarker Masud Parvez ◽  
Rubhana Raqib ◽  
M. Sajjadur Rahman ◽  
...  
Keyword(s):  
Lead Exposure ◽  
Case Control Study ◽  
Blood Lead ◽  
Case Control ◽  
Blood Lead Levels ◽  
Elevated Blood ◽  
Rural Bangladesh ◽  
Lead Levels ◽  
Elevated Blood Lead Levels ◽  
Control Study

Lead Levels in Cord Blood

PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 606-608
Author(s):  
Paul Harris ◽  
Marshall R. Holley
Keyword(s):  
Cord Blood ◽  
Lead Poisoning ◽  
Whole Blood ◽  
Blood Lead ◽  
Mean Value ◽  
Diagnosis And Treatment ◽  
Normal Blood ◽  
Blood Lead Levels ◽  
Lead Levels ◽  
The Mean

Blood lead levels were determined on 24 mothers during labor and on the blood of their newborn offspring. The mean value for the mother's blood lead was 13.2 µg/100 gm (range 10 to 20) and for the cord blood 12.3 (range 10 to 20) µg/100 gm whole blood. These levels are lower than "normal" blood lead standards usually accepted in the diagnosis and treatment of childhood lead poisoning.

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