From the Cover: Evaluation of the Effects of Tanezumab, a Monoclonal Antibody Against Nerve Growth Factor, on the Sympathetic Nervous System in Adult Cynomolgus Monkeys (Macaca fascicularis): A Stereologic, Histomorphologic, and Cardiofunctional Assessment

Patrice Belanger; Paul Butler; Mark Butt; Siddhartha Bhatt; Stephen Foote; David Shelton; Mark Evans; Rosalinda Arends; Susan Hurst; Carlin Okerberg; Thomas Cummings; David Potter; Jill Steidl-Nichols; Mark Zorbas

doi:10.1093/toxsci/kfx089

From the Cover: Evaluation of the Effects of Tanezumab, a Monoclonal Antibody Against Nerve Growth Factor, on the Sympathetic Nervous System in Adult Cynomolgus Monkeys (Macaca fascicularis): A Stereologic, Histomorphologic, and Cardiofunctional Assessment

Toxicological Sciences ◽

10.1093/toxsci/kfx089 ◽

2017 ◽

Vol 158 (2) ◽

pp. 319-333 ◽

Cited By ~ 11

Author(s):

Patrice Belanger ◽

Paul Butler ◽

Mark Butt ◽

Siddhartha Bhatt ◽

Stephen Foote ◽

...

Keyword(s):

Monoclonal Antibody ◽

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Macaca Fascicularis ◽

Nerve Growth ◽

Cynomolgus Monkeys ◽

Sympathetic Nervous

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Morphologic, Stereologic, and Morphometric Evaluation of the Nervous System in Young Cynomolgus Monkeys (Macaca fascicularis) Following Maternal Administration of Tanezumab, a Monoclonal Antibody to Nerve Growth Factor

Toxicological Sciences ◽

10.1093/toxsci/kfu192 ◽

2014 ◽

Vol 142 (2) ◽

pp. 463-476 ◽

Cited By ~ 13

Author(s):

Mark Butt ◽

Mark Evans ◽

Christopher J. Bowman ◽

Thomas Cummings ◽

Satoru Oneda ◽

...

Keyword(s):

Monoclonal Antibody ◽

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Macaca Fascicularis ◽

Nerve Growth ◽

Cynomolgus Monkeys ◽

Maternal Administration ◽

Morphometric Evaluation

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Factors influencing the development of the sympathetic nervous system: trans-synaptic regulation and the influence of nerve growth factor

Biochemical Journal ◽

10.1042/bj1280084p ◽

1972 ◽

Vol 128 (3) ◽

pp. 84P-84P

Author(s):

I A Hendry ◽

L L Iversen

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Nerve Growth ◽

Synaptic Regulation ◽

Factors Influencing ◽

Sympathetic Nervous

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Developmental toxicity assessment of tanezumab, an anti-nerve growth factor monoclonal antibody, in cynomolgus monkeys (Macaca fascicularis)

Reproductive Toxicology ◽

10.1016/j.reprotox.2014.10.004 ◽

2015 ◽

Vol 53 ◽

pp. 105-118 ◽

Cited By ~ 9

Author(s):

Christopher J. Bowman ◽

Mark Evans ◽

Thomas Cummings ◽

Satoru Oneda ◽

Mark Butt ◽

...

Keyword(s):

Monoclonal Antibody ◽

Nerve Growth Factor ◽

Growth Factor ◽

Macaca Fascicularis ◽

Developmental Toxicity ◽

Toxicity Assessment ◽

Nerve Growth ◽

Cynomolgus Monkeys

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Developmental toxicity assessment of tanezumab, an anti-nerve growth factor monoclonal antibody, in Cynomolgus monkeys (Macaca fascicularis)

Reproductive Toxicology ◽

10.1016/j.reprotox.2014.07.007 ◽

2014 ◽

Vol 48 ◽

pp. 14

Author(s):

Christopher J. Bowman ◽

Mark Evans ◽

Thomas Cummings ◽

Satoru Oneda ◽

Mark Butt ◽

...

Keyword(s):

Monoclonal Antibody ◽

Nerve Growth Factor ◽

Growth Factor ◽

Macaca Fascicularis ◽

Developmental Toxicity ◽

Toxicity Assessment ◽

Nerve Growth ◽

Cynomolgus Monkeys

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Increased formation of preganglionic synapses and axons due to a retrograde trans-synaptic action of nerve growth factor in the rat sympathetic nervous system

Journal of Neuroscience ◽

10.1523/jneurosci.03-07-01501.1983 ◽

1983 ◽

Vol 3 (7) ◽

pp. 1501-1510 ◽

Cited By ~ 28

Author(s):

T Schafer ◽

ME Schwab ◽

H Thoenen

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Synaptic Action ◽

Nerve Growth ◽

Sympathetic Nervous

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Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system

Brain Research ◽

10.1016/0006-8993(74)90897-x ◽

1974 ◽

Vol 82 (1) ◽

pp. 117-128 ◽

Cited By ~ 89

Author(s):

Ian A. Hendry ◽

Robert Stach ◽

Karl Herrup

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Axonal Transport ◽

Transport System ◽

Retrograde Axonal Transport ◽

Nerve Growth ◽

Sympathetic Nervous

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CHANGES OF ENZYME PATTERN IN THE SYMPATHETIC NERVOUS SYSTEM OF ADULT MICE AFTER SUBMAXILLARY GLAND REMOVAL; RESPONSE TO EXOGENOUS NERVE GROWTH FACTOR

Journal of Neurochemistry ◽

10.1111/j.1471-4159.1974.tb04328.x ◽

1974 ◽

Vol 22 (6) ◽

pp. 999-1004 ◽

Cited By ~ 27

Author(s):

I. A. Hendry ◽

H. Thoenen

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Submaxillary Gland ◽

Nerve Growth ◽

Adult Mice ◽

Enzyme Pattern ◽

Sympathetic Nervous

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A study of the de- and regenerative changes in the sympathetic nervous system of the adult mouse after treatment with the antiserum to nerve growth factor

Brain Research ◽

10.1016/0006-8993(75)90274-7 ◽

1975 ◽

Vol 92 (2) ◽

pp. 257-278 ◽

Cited By ~ 75

Author(s):

Bo Bjerre ◽

Leif Wiklund ◽

D. Caird Edwards

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Adult Mouse ◽

Nerve Growth ◽

Sympathetic Nervous

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Destruction of the sympathetic nervous system in neonatal rats and hamsters by vinblastine: prevention by concomitant administration of nerve growth factor

Brain Research ◽

10.1016/0006-8993(78)90620-0 ◽

1978 ◽

Vol 141 (1) ◽

pp. 105-118 ◽

Cited By ~ 46

Author(s):

Eugene M. Johnson

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Concomitant Administration ◽

Neonatal Rats ◽

Nerve Growth ◽

Sympathetic Nervous

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Short- and long-term effects of nerve growth factor on the sympathetic nervous system in the adult mouse

Brain Research ◽

10.1016/0006-8993(75)90061-x ◽

1975 ◽

Vol 94 (2) ◽

pp. 263-277 ◽

Cited By ~ 64

Author(s):

Bo Bjerre ◽

Anders Bjo¨rklund ◽

William Mobley ◽

Evald Rosengren

Keyword(s):

Nervous System ◽

Nerve Growth Factor ◽

Growth Factor ◽

Sympathetic Nervous System ◽

Adult Mouse ◽

Long Term Effects ◽

Nerve Growth ◽

Short And Long Term ◽

Sympathetic Nervous

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