scholarly journals Evaluation of different blends of medium-chain fatty acids, lactic acid, and monolaurin on nursery pig growth performance12

2020 ◽  
Vol 4 (2) ◽  
pp. 548-557 ◽  
Author(s):  
Lori L Thomas ◽  
Jason C Woodworth ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Joel M DeRouchey ◽  
...  

Abstract A total of 710 pigs (Line 400 × 200, DNA, Columbus, net energy (NE)) were used in two experiments (Exp. 1: initially, 6.3 ± 0.05 kg; Exp. 2: initially, 6.8 ± 0.05 kg) to evaluate the effects of two medium-chain fatty acid (MCFA) based products on nursery pig growth performance. Following their arrival at the nursery facility, pigs were randomized to pens (five pigs per pen) and allowed a 4-d acclimation period. Thereafter, pens of pigs were blocked by initial weight and randomized to dietary treatment. In Exp. 1, the dietary treatments were a dose titration of: 0%, 0.5%, 1.0%, or 2.0% MCFA-based additive, as well as a diet including 1.0% MCFA from a 1:1:1 blend of C6:0, C8:0, and C10:0. In Exp.2, dietary treatments consisted of a basal diet containing no MCFA (control), the control diet with a 1.0% inclusion of four different blends of MCFA, lactic acid, and monolaurin or a diet with 1.0% added MCFA (a 1:1:1 blend of C6:0, C8:0, and C10:0). The four blends consisted of 50% C6:0, 20% lactic acid, and increasing levels of monolaurin (0%, 10%, 20%, and 30%) at the expense of C12:0 (30%, 20%, 10%, and 0%). Treatment diets were formulated and manufactured in two dietary phases. Data were analyzed as a randomized complete block design with pen as the experimental unit. In Exp. 1, overall (days 0–34), increasing CaptiSURE increased (linear, P ≤ 0.014) average daily gain (ADG) and average daily feed intake (ADFI). Feed efficiency improved (quadratic, P = 0.002) with increasing CaptiSURE up to 1.0% of the diet with no benefit thereafter. There was no evidence for differences between pigs fed 1.0% CaptiSURE and pigs fed the 1.0% MCFA blend of C6:0, C8:0, and C10:0. In Exp. 2, overall (days 0–35), pigs fed the 1.0% 1:1:1 MCFA blend had increased (P < 0.034) ADFI and ADG resulting in 0.9 kg greater final weight (P = 0.014) compared with the control group. There was no evidence that the mean performance of pigs fed the four blends of MCFA, lactic acid, and monolaurin were different from the pigs fed the control diet. In summary, the addition of a 1.0% 1:1:1 blend of C6:0, C8:0, and C10:0 in nursery pig diets improved ADG, ADFI, and gain to feed ratio (G:F) compared with pigs fed the control diet. In addition, providing nursery pigs with the MCFA product CaptiSURE, up to 2% of the diet, resulted in linear improvements in ADG and ADFI. Altering the C12:0 to monolaurin ratio and adding lactic acid did not improve growth performance compared with pigs fed the control diet.

Author(s):  
Siriporn Namted ◽  
Theerawit Poeikhampha ◽  
Choawit Rakangthong ◽  
Chaiyapoom Bunchasak

The study was conducted to determine the effect of supplemental capsaicin (CS) or capsaicin plus DL-methionine hydroxy analog (CS+LMA) in diets on growth performance and gastrointestinal conditions of nursery pigs. Seventy-two castrated male piglets (BW 7.79 ± 0.02 kg) were offered diets for 6 weeks as follows: 1) control diet, 2) control diet with capsaicin 2.5 ppm (CS), and 3) control diet with capsaicin 2.5 ppm plus DL-LMA 0.05 % (CS+LMA). The dietary treatments did not influence growth performance, gastrointestinal pH and the bacterial population in the caecum (P>0.05). However, in the caecum, number of Lactobacillus spp. tended to increase (P=0.09), and lactic acid concentration was increased (P less than 0.05) by CS+LMA supplementation. The supplemental CS or CS+LMA increased the villus height (P less than 0.01), and CS+LMA supplementation increased the crypt depth (P less than 0.05) in the segment of duodenum compared to the control group. The blood urea nitrogen (BUN) was not influenced by CS or CSLMA supplementations (P>0.05). In conclusion, supplementing CS improved the small intestinal morphology, and there were synergistic effects on the duodenal crypt depth and caecal lactic acid when LMA was combined with CS.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 80-81
Author(s):  
Lori L Thomas ◽  
Ashley Hartman ◽  
Jason C Woodworth ◽  
Mike D Tokach ◽  
Robert D Goodband ◽  
...  

Abstract A total of 360 pigs (DNA 400×200, initial BW=6.8 kg) were used a 35-d trial to evaluate the effects of adding MCFA and monolaurin blends to the diet on growth performance of nursery pigs. Pens of pigs were blocked by BW and randomized to 1 of 6 dietary treatments (12 pens per treatment). Treatments consisted of a basal diet containing no MCFA (control), the control diet with 1.0% added MCFA (a 1:1:1 blend of C6, C8, and C10; Sigma Aldrich, St. Louis, MO), or a 1.0% inclusion of 4 different blends of MCFA, lactic acid, and monolaurin (1, 2, 3, and 4). The 4 blends consisted of 50% C6, 20% lactic acid and increasing levels of monolaurin (0, 10, 20, and 30%) at the expense of C12 (30, 20, 10, and 0%). Data were analyzed as a randomized complete block design with pen as the experimental unit. From d 0 to 14, pigs fed the 1.0% 1:1:1 MCFA blend had increased (P = 0.037) ADG compared to the control group. Pigs fed the 1.0% 1:1:1 MCFA blend and the mean of the 4 blends of MCFA, lactic acid, and monolaurin had improved (P < 0.037) G:F compared with pigs fed the control diet. From d 14 to 35, ADFI and subsequently ADG increased (P < 0.057) for pigs fed the 1.0% 1:1:1 MCFA blend compared with the control group. Overall, pigs fed the 1.0% 1:1:1 MCFA blend had increased (P < 0.034) ADFI and ADG, resulting in 0.9 kg greater final BW (P = 0.014) compared with the control group. There was no evidence for differences between the mean of pigs fed blends of MCFA, lactic acid, and monolaurin compared with the control. In summary, the addition of a 1.0% 1:1:1 MCFA blend resulted in improved ADG, ADFI, and G:F compared with pigs fed a control diet.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 118-118
Author(s):  
Yi-Chi Cheng ◽  
Marcos E Duarte ◽  
Sung Woo Kim

Abstract The objective was to evaluate Yarrowia lipolytica (YL) as a lipid supplement fed to nursery pigs for the growth performance and apparent ileal digestibility (AID). Twenty-four pigs weaned at 21 d of age (12 barrows and 12 gilts with initial BW at 7.2 ± 0.6 kg) were allotted to 3 dietary treatments (n = 8) based on the randomized complete block design with sex and BW as blocks. The main effect was the dietary supplementation of YL (0, 1.5, and 3.0%, replacing poultry fat) with nutrients meeting or exceeding the requirements by NRC (2012) and fed to pigs for 21 d based on 2 phases. Feed intake and BW were recorded at d 0, 10, and 21 to calculate ADG, ADFI, and G:F. Fecal scores were recorded at every odd day from d 3 to 19. Pigs were euthanized on d 21 to collect ileal digesta for AID of nutrients in diets. Data were analyzed using Proc Mixed of SAS. There were no differences in growth performance among treatments. Whereas, pigs fed 0 and 1.5% YL had higher (P &lt; 0.05) AID of DM (55.0 and 52.2% to 40.2%, respectively) and GE (62.1 and 60.6% to 49.8%, respectively) than pigs fed 3% YL. There were no differences in AID of DM and GE between the pigs fed 0% and 1.5% YL. In conclusion, 1.5% Yarrowia lipolytica could be supplemented in nursery pig diets reducing 0.8% of poultry fat without affecting growth performance and AID of DM and GE.


2018 ◽  
Vol 2 (2) ◽  
pp. 169-183 ◽  
Author(s):  
Pedro E Urriola ◽  
Joey A Mielke ◽  
Qingqing Mao ◽  
Yuan-Tai Hung ◽  
John F Kurtz ◽  
...  

Abstract Although microalgae can be used as a source of energy and macronutrients in pig diets, there is limited information on the use of partially de-oiled microalgae coproducts in swine feeding programs. The objectives of this study were to evaluate the effects of a partially de-oiled microalgae extract (MAE) in nursery pig diets on growth performance and health status. A total of 300 pigs (initial BW = 6.3 ± 2.1 kg) were used in a 42-d experiment. Treatments included a standard corn-soybean meal control diet, and diets containing 1, 5, 10, or 20% MAE replacing primarily corn. The ME content of MAE was calculated from the chemical composition, and diets were formulated to meet or exceed nutrient requirements for nursery pigs. Pigs were stratified by weaning BW into 12 blocks in a randomized complete block design, with sex distributed evenly among blocks. Pens of pigs (5 pigs/pen) were assigned randomly within block to one of five dietary treatments. Pig BW and feed disappearance were recorded weekly. On day 42, 30 pigs were harvested and sections of the jejunum and ileum were collected for gut morphology analysis, and a liver sample was collected for metabolomic analysis using liquid chromatography-mass spectroscopy. Data were analyzed by ANOVA with diet as treatment effect, and contrasts were used to test linear or quadratic effects of dietary MAE inclusion level. Overall, pigs fed 1% and 5% MAE had the greatest (quadratic P &lt; 0.05) ADG, resulting from greater (quadratic P &lt; 0.05) ADFI. There was a tendency for a greater number of pigs requiring injectable treatments (P = 0.16) and a greater mortality (P = 0.14) in pigs fed the control diet than pigs in any of the diets with the MAE. Final BW increased (P &lt; 0.05) for pigs fed 1% and 5% MAE diets. The improvements in ADG were not explained by differences in mucosa height or goblet cell count among dietary treatments. Pigs fed diets containing 1% or 5% MAE had relatively less concentration (P &lt; 0.05) of ammonia in the liver and had changes in metabolites associated with the urea cycle. In conclusion, feeding MAE resulted in increased growth responses and may have beneficial health effects when fed to nursery pigs.


2017 ◽  
Vol 60 (No. 12) ◽  
pp. 675-682
Author(s):  
S. Mohana Devi ◽  
SC Kim ◽  
IH Kim

A total of 120 weanling pigs [(Landrace &times; Yorkshire) &times; Duroc], 21 days of age with an average initial body weight (BW) of 6.52 &plusmn; 0.22 (SE) kg were selected to investigate the effects of extruded rice product as a replacement for dried whey on growth performance, coefficient of total tract apparent digestibility (CATTD), blood profiles, faecal shedding of Lactobacillus and Escherichia coli (the microbial counts of digesta were expressed as log<sub>10</sub> colony forming units per gram), and faecal scores of weanling pigs. Pigs were randomly allocated to one of four dietary treatments, with six replicates per treatment and five pigs per pen. Pigs in the control group were fed a diet based on corn, soybean, and 20% dried whey. Experimental groups received the same diet as the control group, but dried whey was replaced by 3%, 6%, and 9% extruded rice. Throughout the experimental period (six weeks), no differences were observed in the average daily gain, average daily feed intake, and gain/feed ratio. Pigs fed 6% and 9% extruded rice had a lower (P &lt; 0.05) CATTD than pigs fed the control diet on Day 14. The blood creatinine concentration of pigs fed 9% extruded rice was higher (P &lt; 0.05) than that of pigs in the control group on Day 14. Pigs fed the diets containing 6% and 9% extruded rice had decreased (P &lt; 0.05) faecal E. coli counts on Day 14 compared with pigs fed the control diet. The current results indicate that feeding extruded rice can decrease faecal E. coli counts without negative effects on growth performance in weanling pigs.


2014 ◽  
Vol 54 (7) ◽  
pp. 966 ◽  
Author(s):  
Pietro Celi ◽  
Peter H. Selle ◽  
Aaron J. Cowieson

The effects of organic selenium (Se) supplementation of diets for broiler chickens were evaluated in the present study. Broiler diets had average background Se concentrations of 0.36 mg/kg Se (control diet) and were supplemented with two organic Se sources, namely BiOnyc® Tor-Sel (selenohomolanthionine = SH) and Alltech’s Sel PlexTM (selenomethionine = SM); their addition increased dietary selenium concentrations by an average of 0.57 mg/kg Se. Their effects on growth performance, nutrient utilisation and oxidative status of broiler chickens were determined. Growth performance was very similar across all dietary treatments; in contrast, significant differences in nutrient utilisation were observed. The N-corrected apparent metabolisable energy value for the control group (14.14 MJ/kg) and SH (14.15 MJ/kg) diet was significantly (P < 0.01) higher than that for the SM (13.64 MJ/kg) diet. Alternatively, N retention with the SM (68.4%) diet was significantly (P < 0.005) higher than that for the control (65.2%) and SH (64.5%) diets. Neither of the Se sources influenced plasma concentrations of reactive oxygen metabolites, biological antioxidant potential and advanced oxidation protein products. The activity of glutathione peroxidase, superoxide dismutase in both plasma and tissues samples and the concentration of plasma glutathione were increased by SH and SM compared with the control group. Our findings suggest that SH and SM improved the antioxidant status of broilers by elevating activities of antioxidant enzymes and concentrations of antioxidant. Both Se supplements significantly (P < 0.001) increased Se concentrations in liver and muscle, and in liver tissue there was no statistical difference between the two supplements. However, SH generated significantly higher Se concentrations in muscle tissue (0.283 versus 0.257; P < 0.005) than did SM. In summary, SH was at least the equivalent to SM as a source of organic Se for broiler chickens under the conditions of the present feeding study. This is reflected in the outcome that SH generated significantly higher Se concentrations in muscle tissue than did the alternative Se supplement.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 46-46
Author(s):  
Katelyn M Zeamer ◽  
Ryan S Samuel ◽  
Robert C Thaler ◽  
Tofuko A Woyengo ◽  
Crystal L Levesque

Abstract This study evaluated a low allergen (P34 protein) and low anti-nutritional factor (trypsin inhibitor and lectin) in both soybean meal form (LASBM) and full fat ground soybean form (LAGR) as substitutes for fishmeal (FM) in nursery pig diets based on growth performance. Weaned pigs (n = 112; 7.30 ± 0.43 kg BW) were allotted to 28 pens (2 barrows and 2 gilts per pen) by initial BW. Pens (n = 7/diet) were randomly assigned to one of 4 dietary treatments in 2 phases (Ph1 = 5d, Ph2 = 13d): control diet containing FM (7.25%, Ph1; 6%, Ph2), and LASBM, LAGR or conventional SBM substituted for FM to supply an equivalent portion of crude protein. Pigs received a common Ph3 diet (18 d). Pig weight and feed disappearance was determined by phase. Data was analyzed as a one-way ANOVA. Model included main effect of diet with pen as experimental unit. In Ph1, pigs fed FM had lower (P < 0.01) ADG than LAGR or SBM and lower (P < 0.01) ADFI than all diets. In Ph2, SBM-fed pigs had higher (P < 0.01) ADG and ADFI compared to all treatments. Pigs previously fed LAGR tended to have higher gain (P < 0.10) than pigs previously fed LASBM in Ph3. There were no differences in gain:feed between diets. Based on growth performance, LAGR would be suitable replacement for FM in nursery diets.


2019 ◽  
Vol 98 (1) ◽  
Author(s):  
Jordan T Gebhardt ◽  
Katelyn A Thomson ◽  
Jason C Woodworth ◽  
Steve S Dritz ◽  
Michael D Tokach ◽  
...  

Abstract An experiment was conducted to evaluate the effect of dietary medium-chain fatty acid (MCFA) addition on nursery pig growth performance, fecal microbial composition, and mitigation of porcine epidemic diarrhea virus (PEDV) following storage. A total of 360 pigs (DNA 400 × 200, Columbus, NE; initially 6.7 ± 0.07 kg) were randomized to pens (5 pigs per pen) on the day of weaning (approximately 20 d of age), allowed a 6-d acclimation, blocked by BW, and randomized to dietary treatment (9 pens per treatment). All MCFA (Sigma–Aldrich, St. Louis, MO) were guaranteed ≥98% purity, including hexanoic (C6:0), octanoic (C8:0), and decanoic (C10:0) acids. Treatment diets were formulated in 2 phases (7 to 11 and 11 to 23 kg BW) and formulated to meet or exceed NRC requirement estimates. Treatments (n = 8) were a dose response including 0%, 0.25%, 0.5%, 1.0%, and 1.5% added MCFA blend (1:1:1 ratio C6:0, C8:0, and C10:0), as well as treatments with individual additions of 0.5% C6:0, C8:0, or C10:0. Fecal samples were collected from pigs fed control and 1.5% MCFA blend diets on days 0 and 14 and analyzed using 16s rDNA sequencing. Following feed manufacture, feed was stored in bags at barn temperature and humidity for 40 d before laboratory inoculation with PEDV. Subsamples of retained feed were inoculated with PEDV to achieve a titer of 104 TCID50/g and separate sample bottles were analyzed on 0 and 3 d post-inoculation (dpi). Overall, ADG and ADFI were increased (linear, P ≤ 0.010) and feed efficiency (G:F) improved (linear, P = 0.004) with increasing MCFA blend. Pigs fed 0.5% C8:0 had greater (P = 0.038) ADG compared with pigs fed the control diet, and G:F was improved (P ≤ 0.024) when pigs were fed 0.5% C6:0, 0.5% C8:0, or 0.5% C10:0 compared with control. An inclusion level × day interaction was observed (quadratic, P = 0.023), where PEDV Ct values increased (quadratic, P = 0.001) on 0 dpi with increasing levels of MCFA blend inclusion and also increased on 3 dpi (linear, P &lt; 0.001). Fecal microbial diversity and composition were similar between control and 1.5% MCFA blend. In summary, the use of MCFA in nursery pig diets improves growth performance, provides residual mitigation activity against PEDV, and does not significantly alter fecal microbial composition.


2020 ◽  
Vol 98 (7) ◽  
Author(s):  
Hayden E Williams ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steven S Dritz ◽  
Michael D Tokach ◽  
...  

Abstract A total of 140 weanling pigs (241 × 600, DNA, Columbus, NE; initially 5.5 ± 0.79 kg body weight) were used in a 32-d study evaluating the effects of increasing dietary Fe from either iron sulfate (FeSO4) or iron carbonate (FeCO3) on nursery pig growth performance and blood Fe status. The pigs used for this trial did not receive an Fe injection after birth in order to increase the sensitivity to added dietary Fe after weaning. Pigs were weaned at approximately 21 d and allotted to pens based on the initial weight in a completely randomized block design with five pigs in each pen and four pens per treatment. Experimental treatments were arranged as a 2 × 3 + 1 factorial with main effects of dietary Fe source (FeSO4 vs. FeCO3) and level (10, 30, or 50 mg/kg of added Fe) plus a negative control with no additional dietary Fe. The basal diet contained 40 mg/kg total dietary Fe based on ingredient contributions and was formulated with an Fe-free trace mineral premix. Experimental diets were formulated below the pigs recommended Fe requirement based on NRC (2012) estimates. Experimental diets were fed in pellet form in a single phase for the duration of the trial. From day 0 to 32, there was no evidence for source × level interactions for growth performance, hemoglobin (Hb), or hematocrit (Hct) values. There was no evidence for a difference (P &gt; 0.10) in dietary Fe source. Providing increasing Fe levels in the diet from either FeSO4 or FeCO3 improved (P &lt; 0.05) average daily gain, average daily feed intake, gain-to-feed ratio, and increased (P &lt; 0.05) Hb and Hct values. A day effect (P = 0.001) was observed for both Hb and Hct with values increasing throughout the study. Increasing dietary Fe levels in the diet from either FeSO4 or FeCO3 increased (linear; P &lt; 0.05) Hb and Hct values on days 14, 21, and 32. In summary, these data suggest that the micronized form of FeCO3 is a source of Fe that can be added to nursery diets to yield similar responses to those observed from FeSO4 supplementation. Similar to previous research, increasing dietary Fe improved the growth performance and increased Hb and Hct values when pigs have low Fe status at weaning.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 57-58
Author(s):  
Uislei Orlando ◽  
Ning Lu ◽  
Carine Vier ◽  
Wayne Cast ◽  
Xun Zhou ◽  
...  

Abstract Our objective was to determine the effects of feeding different neutral detergent fiber (NDF) and standardized ileal digestible (SID) lysine (Lys) levels on performance of growing-finishing pigs from 30- to 130-kg. A total of 2,016 barrows and gilts (PIC 280×Camborough, initial BW of 29.6±0.53 kg) were allotted to a randomized complete block design with a 2×2 factorial arrangement. Dietary treatments (Table 1) consisted with two NDF levels (13% or 20%) and two SID Lys curves (PIC2008 or PIC2016). There were 21 mixed-sex pigs per pen, and 24 pens per treatment. The experiment diets were fed in 3 phases. Wheat, wheat by-products, peas, and canola oil were used with NRC (2012) loading values to achieve treatments, and all diets were formulated to be iso-caloric (2,420 kcal NE/kg). Experimental data were analyzed using generalized linear mixed models with pen as the experimental unit. Increasing NDF level resulted in a reduction (P&lt; 0.05) in average daily gain (ADG), average daily feed intake, hot carcass weight, carcass yield, carcass ADG, and backfat depth (Table 2), and tended to decrease percentage of removals and mortality (P=0.10). Pigs fed PIC2016 Lys curve had greater ADG and carcass ADG as compared to those fed PIC2008 Lys curve (P&lt; 0.05). There were NDF×Lys interactions (P&lt; 0.10) for ADG, gain to feed ratio (G:F), carcass ADG, and carcass G:F. These response criteria were improved for pigs fed PIC2016 Lys curve compared to those fed PIC2008 Lys curve when NDF level was 13%; while no evidence of differences was observed at 20% NDF. Results indicate that increasing NDF level from 13 to 20% deteriorate performance of 30- to 130- kg pigs; and the improved growth performance of pigs fed PIC2016 Lys curve as compared to those fed PIC2008 Lys curve was only observed when lower NDF level was presented.


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