scholarly journals Erectile Dysfunction in Men with Obstructive Sleep Apnea: An Early Sign of Nerve Involvement

SLEEP ◽  
2000 ◽  
Vol 23 (6) ◽  
pp. 1-7 ◽  
Author(s):  
Francesco Fanfulla ◽  
Silvia Malaguti ◽  
Tiziana Montagna ◽  
Silvana Salvini ◽  
Claudio Bruschi ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Erectile Dysfunction ◽  
Sleep Apnea ◽  
Early Sign ◽  
Nerve Involvement ◽  
Obstructive Sleep

scholarly journals Erectile dysfunction in obstructive sleep apnea patients: A randomized trial on the effects of Continuous Positive Airway Pressure (CPAP)

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201930 ◽  
Author(s):  
Mercè Pascual ◽  
Jordi de Batlle ◽  
Ferran Barbé ◽  
Anabel L. Castro-Grattoni ◽  
Josep M. Auguet ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Erectile Dysfunction ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Randomized Trial ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Obstructive Sleep

scholarly journals Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Izolde Bouloukaki ◽  
Vaios Papadimitriou ◽  
Frank Sofras ◽  
Charalampos Mermigkis ◽  
Violeta Moniaki ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Erectile Dysfunction ◽  
Sleep Apnea ◽  
Endothelial Dysfunction ◽  
Statistical Significance ◽  
High Sensitivity ◽  
Reactive Protein ◽  
Obstructive Sleep ◽  
The Difference ◽  
Hypopnea Syndrome

Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) show a high prevalence of erectile dysfunction (ED). Although the underlying pathogenesis is still unknown, endothelial dysfunction, induced by inflammatory cytokines, chemokines, and adhesion molecules, has been proposed as a possible mechanism. The aim of this study was to assess whether OSAHS is associated with activation of the inflammatory cytokine system in patients with ED compared to the matched OSAHS patients with normal sexual function. Thirty-one patients with severe OSAHS and ED were included. Fifteen patients with severe OSAHS and without ED served as controls. Serum concentrations of high-sensitivity C-reactive protein (hsCRP), tumor necrosis factor-α(TNF-a), interleukin-6 (IL-6), interleukin-8 (IL-8), and adiponectin were measured after the diagnostic polysomnography. We found that hsCRP levels were significantly elevated in OSAHS patients with ED compared to controls. Similarly, TNF-a levels, IL-6, and IL-8 were elevated in OSAHS patients with ED compared to controls. Serum adiponectin levels were lower in OSAHS-ED patients, but the difference did not reach statistical significance. The presence of ED in patients with severe OSAHS is associated with elevated levels of inflammatory markers, underlining a possible involvement of endothelial dysfunction in the pathogenesis of ED.

Sildenafil combined with continuous positive airway pressure for treatment of erectile dysfunction in men with obstructive sleep apnea

2007 ◽  
Vol 39 (2) ◽  
pp. 547-552 ◽  
Author(s):  
Petros Perimenis ◽  
Angelis Konstantinopoulos ◽  
Kyriakos Karkoulias ◽  
Spyros Markou ◽  
Paraskevi Perimeni ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Erectile Dysfunction ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Obstructive Sleep
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