scholarly journals Dreams and Rapid Eye Movement Sleep in the Multiple Sleep Latency Test

SLEEP ◽  
1995 ◽  
Vol 18 (2) ◽  
pp. 105-108 ◽  
Author(s):  
Selim R. Benbadis ◽  
Barbara R. Wolgamuth ◽  
Michael C. Perry ◽  
Dudley S. Dinner
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Multiple Sleep Latency Test ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Multiple Sleep Latency

Two cases of HLA‐DR2‐negative hypersomnia manifesting sleep‐onset rapid eye movement periods in the multiple sleep latency test

1999 ◽  
Vol 53 (2) ◽  
pp. 295-297
Author(s):  
Yasushi Yoshida ◽  
Kenji Kuroda ◽  
Masaharu Mandai ◽  
Seiji Satani ◽  
Narutsugu Emura ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Sleep Onset ◽  
Multiple Sleep Latency Test ◽  
Rapid Eye Movement ◽  
Multiple Sleep Latency

scholarly journals Compromised Dynamic Cerebral Autoregulation in Patients With Central Disorders of Hypersomnolence

2021 ◽  
Vol 12 ◽  
Author(s):  
Fang Deng ◽  
Yanan Zhang ◽  
Ran Zhang ◽  
Qi Tang ◽  
Zhenni Guo ◽  
...  
Keyword(s):  
Eye Movement ◽  
Cerebral Autoregulation ◽  
Sleep Latency ◽  
Behavior Disorder ◽  
Multiple Sleep Latency Test ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior ◽  
Multiple Sleep Latency ◽  
Dynamic Cerebral Autoregulation

Objective: We aimed to investigate the dynamic cerebral autoregulation (dCA) in patients with central disorders of hypersomnolence during wakefulness.Methods: Thirty-six patients with central disorders of hypersomnolence were divided into three groups according to polysomnography and multiple sleep latency test results: the idiopathic hypersomnia group (IH), narcolepsy type 1 without rapid-eye-movement sleep behavior disorder group (NT1-RBD), and narcolepsy type 1 with rapid-eye-movement sleep behavior disorder group (NT1 + RBD), with 12 patients in each group. Twelve sex- and age-matched healthy controls were recruited. We assessed the Epworth sleepiness scale (ESS) and dCA of all subjects. dCA was assessed by analyzing the phase difference (PD) using transfer function analysis. The ESS and dCA were analyzed before and after standardized treatment in 24 patients with narcolepsy type 1.Results: The overall PD of the IH, NT1-RBD, and NT1 + RBD groups were lower than that of the control group (P < 0.001). There were no significant differences between the overall PD of the NT1-RBD and NT1 + RBD group (P > 0.05). The ESS scores decreased and the overall PD increased after treatment in 24 patients with narcolepsy type 1 (P < 0.001). Multivariable analysis showed that mean sleep latency in multiple sleep latency test was independently associated with impaired overall PD (P < 0.05).Conclusions: The dCA is impaired in patients with central disorders of hypersomnolence. The impairment of dCA occurs irrespective of NT1-RBD/+RBD. The ESS score and dCA improved in patients with narcolepsy type 1 after medication treatment. The mean sleep latency in multiple sleep latency test was independently associated with impaired dCA.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT02752139.

scholarly journals 0738 Advance Taper of Antidepressants Prior to Multiple Sleep Latency Testing Increases the Number of Sleep-Onset Rapid Eye Movement Periods and Reduces Mean Sleep Latency

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A281-A281
Author(s):  
B Kolla ◽  
M Jahani Kondori ◽  
M Silber ◽  
H Samman ◽  
S Dhankikar ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Sleep Onset ◽  
Initial Assessment ◽  
Rapid Eye Movement ◽  
Regression Analyses ◽  
Practice Parameters ◽  
The Impact ◽  
Multiple Sleep Latency ◽  
Multiple Sleep Latency Testing

Abstract Introduction Patients presenting with excessive sleepiness are frequently on antidepressant medication(s). While practice parameters recommend discontinuation of antidepressants prior to multiple sleep latency testing (MSLT), data examining the impact of tapering these medications on MSLT results are limited. Methods Adult patients who underwent MSLT at Mayo Clinic Rochester, Minnesota, between 2014-2018 were included. Clinical and demographic characteristics, medications, including use of rapid eye movement suppressing antidepressants (REMS-AD) at assessment and during testing, actigraphy and polysomnography data were manually abstracted. The difference in number of sleep-onset rapid eye movement periods (SOREMS), proportion with ≥2 SOREMS and mean sleep latency (MSL) in patients who were on REMS-AD and discontinued prior to testing versus those who remained on REMS-AD were examined. At our center, all antidepressants are discontinued 2 weeks prior to MSLT wherever feasible; fluoxetine is stopped 4 weeks prior. Regression analyses accounting for demographic, clinical and other medication-related confounders were performed. Results A total of 502 patients (age=38.18±15.90 years; 67% female) underwent MSLT; 178 (35%) were on REMS-AD at the time of assessment. REMS-AD were discontinued prior to testing in 121/178 (70%) patients. Patients tapered off REMS-AD were more likely to have ≥2 SOREMS (OR-12.20; 95%CI=1.60-92.94) compared to patients who remained on REMS-AD at the time of the MSLT. They also had shorter MSL (8.77±0.46 vs 10.21±0.28; p>0.009) and higher odds of having ≥2 SOREMS (OR=2.22; 95%CI=1.23-3.98) compared to patients not on REMS-AD at initial assessment. These differences persisted after regression analyses accounting for confounders. Conclusion Patients who taper off REMS-AD prior to MSLT are more likely to demonstrate ≥2SOREMs and have a shorter MSL. Pending further prospective investigations, clinicians should preferably withdraw REMs-AD before an MSLT. If this is not done, the test interpretation should include a statement regarding the potential effect of the drugs on the results. Support None

scholarly journals Nocturnal Rapid Eye Movement Sleep Latency for Identifying Patients With Narcolepsy/Hypocretin Deficiency

2013 ◽  
Vol 70 (7) ◽  
pp. 891 ◽  
Author(s):  
Olivier Andlauer ◽  
Hyatt Moore ◽  
Laura Jouhier ◽  
Christopher Drake ◽  
Paul E. Peppard ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep

Reduced rapid eye movement sleep latency in patients with parkinson's disease

1989 ◽  
Vol 236 (7) ◽  
pp. 421-423 ◽  
Author(s):  
V. S. Kostić ◽  
V. Šušić ◽  
N. Čovičković-Šternić ◽  
Z. Marinković ◽  
S. Janković
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Sleep Latency ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep

scholarly journals HLA-DR2 AND RAPID-EYE-MOVEMENT SLEEP LATENCY: FAILURE TO REPLICATE

The Lancet ◽  
1987 ◽  
Vol 329 (8533) ◽  
pp. 627 ◽  
Author(s):  
H. Schulz ◽  
P. Geisler ◽  
T. Pollmaecher ◽  
A. Andreas-Zietz ◽  
E. Keller ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep

scholarly journals HLA-DR2 CORRELATES WITH RAPID-EYE-MOVEMENT SLEEP LATENCY IN NORMAL HUMAN SUBJECTS

The Lancet ◽  
1986 ◽  
Vol 328 (8510) ◽  
pp. 803 ◽  
Author(s):  
H. Schulz ◽  
P. Geisler ◽  
T. Pollmaecher ◽  
A. Andreas-Zietz ◽  
E. Keller ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Human Subjects ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Normal Human

scholarly journals Advance taper of antidepressants prior to multiple sleep latency testing increases the number of sleep-onset rapid eye movement periods and reduces mean sleep latency

2020 ◽  
Vol 16 (11) ◽  
pp. 1921-1927
Author(s):  
Bhanu Prakash Kolla ◽  
Marjan Jahani Kondori ◽  
Michael H. Silber ◽  
Hala Samman ◽  
Swati Dhankikar ◽  
...  
Keyword(s):  
Eye Movement ◽  
Sleep Latency ◽  
Sleep Onset ◽  
Rapid Eye Movement ◽  
Multiple Sleep Latency ◽  
Multiple Sleep Latency Testing
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