scholarly journals Age-related differences in neural activities during risk taking as revealed by functional MRI

2007 ◽  
Vol 3 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Tatia M. C. Lee ◽  
Ada W. S. Leung ◽  
Peter T. Fox ◽  
Jia-Hong Gao ◽  
Chetwyn C. H. Chan
2021 ◽  
Vol 13 ◽  
Author(s):  
Shuai Guan ◽  
Xiangyu Kong ◽  
Shifei Duan ◽  
Qingguo Ren ◽  
Zhaodi Huang ◽  
...  

White matter hyperintensity (WMH) is common in healthy adults in their 60s and can be seen as early as in their 30s and 40s. Alterations in the brain structural and functional profiles in adults with WMH have been repeatedly studied but with a focus on late-stage WMH. To date, structural and functional MRI profiles during the very early stage of WMH remain largely unexplored. To address this, we investigated multimodal MRI (structural, diffusion, and resting-state functional MRI) profiles of community-dwelling asymptomatic adults with very early-stage WMH relative to age-, sex-, and education-matched non-WMH controls. The comparative results showed significant age-related and age-independent changes in structural MRI-based morphometric measures and resting-state fMRI-based measures in a set of specific gray matter (GM) regions but no global white matter changes. The observed structural and functional anomalies in specific GM regions in community-dwelling asymptomatic adults with very early-stage WMH provide novel data regarding very early-stage WMH and enhance understanding of the pathogenesis of WMH.


NeuroImage ◽  
2020 ◽  
Vol 218 ◽  
pp. 116976 ◽  
Author(s):  
Andrew Crofts ◽  
Melissa Trotman-Lucas ◽  
Justyna Janus ◽  
Michael Kelly ◽  
Claire L. Gibson

2006 ◽  
Vol 1076 (1) ◽  
pp. 171-176 ◽  
Author(s):  
Tatia M.C. Lee ◽  
John X. Zhang ◽  
Chetwyn C.H. Chan ◽  
Kenneth S.L. Yuen ◽  
L.W. Chu ◽  
...  
Keyword(s):  

Author(s):  
Sanae Kato ◽  
Epifanio Bagarinao ◽  
Haruo Isoda ◽  
Shuji Koyama ◽  
Hirohisa Watanabe ◽  
...  

2018 ◽  
Vol 374 (1766) ◽  
pp. 20180133 ◽  
Author(s):  
Gail M. Rosenbaum ◽  
Catherine A. Hartley

Epidemiological data suggest that risk taking in the real world increases from childhood into adolescence and declines into adulthood. However, developmental patterns of behaviour in laboratory assays of risk taking and impulsive choice are inconsistent. In this article, we review a growing literature using behavioural economic approaches to understand developmental changes in risk taking and impulsivity. We present findings that have begun to elucidate both the cognitive and neural processes that contribute to risky and impulsive choice, as well as how age-related changes in these neurocognitive processes give rise to shifts in choice behaviour. We highlight how variability in task parameters can be used to identify specific aspects of decision contexts that may differentially influence risky and impulsive choice behaviour across development. This article is part of the theme issue ‘Risk taking and impulsive behaviour: fundamental discoveries, theoretical perspectives and clinical implications’.


2010 ◽  
Vol 30 (4) ◽  
pp. 1426-1434 ◽  
Author(s):  
G. R. Samanez-Larkin ◽  
C. M. Kuhnen ◽  
D. J. Yoo ◽  
B. Knutson

2014 ◽  
Vol 42 (3) ◽  
pp. 729-736 ◽  
Author(s):  
Li Dong ◽  
Cheng Luo ◽  
Weifang Cao ◽  
Rui Zhang ◽  
Jinnan Gong ◽  
...  

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