scholarly journals Computational Methods in Social Neuroscience: Recent Advances, New Tools, and Future Directions

Author(s):  
Carolyn Parkinson

Abstract Recent years have seen a surge of exciting developments in the computational tools available to social neuroscientists. This paper highlights and synthesizes recent advances that have been enabled by the application of such tools, as well as methodological innovations likely to be of interest and utility to social neuroscientists, but that have been concentrated in other sub-fields. Papers in this special issue are emphasized, many of which contain instructive materials (e.g., tutorials, code) for researchers new to the highlighted methods. These include approaches for modeling social decisions, characterizing multivariate neural response patterns at varying spatial scales, using decoded neurofeedback to draw causal links between specific neural response patterns and psychological and behavioral phenomena, examining time-varying patterns of connectivity between brain regions, and characterizing the social networks in which social thought and behavior unfold in everyday life. By combining computational methods for characterizing participants’ rich social environments – at the levels of stimuli, paradigms, and the webs of social relationships that surround people – with those for capturing the psychological processes that undergird social behavior and the wealth of information contained in neuroimaging datasets, social neuroscientists can gain new insights into how people create, understand, and navigate their complex social worlds.

2020 ◽  
Vol 14 ◽  
Author(s):  
Richard Huskey ◽  
Benjamin O. Turner ◽  
René Weber

Prevention neuroscience investigates the brain basis of attitude and behavior change. Over the years, an increasingly structurally and functionally resolved “persuasion network” has emerged. However, current studies have only identified a small handful of neural structures that are commonly recruited during persuasive message processing, and the extent to which these (and other) structures are sensitive to numerous individual difference factors remains largely unknown. In this project we apply a multi-dimensional similarity-based individual differences analysis to explore which individual factors—including characteristics of messages and target audiences—drive patterns of brain activity to be more or less similar across individuals encountering the same anti-drug public service announcements (PSAs). We demonstrate that several ensembles of brain regions show response patterns that are driven by a variety of unique factors. These results are discussed in terms of their implications for neural models of persuasion, prevention neuroscience and message tailoring, and methodological implications for future research.


Author(s):  
Maren N. Vitousek ◽  
Laura A. Schoenle

Hormones mediate the expression of life history traits—phenotypic traits that contribute to lifetime fitness (i.e., reproductive timing, growth rate, number and size of offspring). The endocrine system shapes phenotype by organizing tissues during developmental periods and by activating changes in behavior, physiology, and morphology in response to varying physical and social environments. Because hormones can simultaneously regulate many traits (hormonal pleiotropy), they are important mediators of life history trade-offs among growth, reproduction, and survival. This chapter reviews the role of hormones in shaping life histories with an emphasis on developmental plasticity and reversible flexibility in endocrine and life history traits. It also discusses the advantages of studying hormone–behavior interactions from an evolutionary perspective. Recent research in evolutionary endocrinology has provided insight into the heritability of endocrine traits, how selection on hormone systems may influence the evolution of life histories, and the role of hormonal pleiotropy in driving or constraining evolution.


Author(s):  
Scott N. Brooks

Conducting ethnographic fieldwork in varied spaces, with different actors, enriches our understanding. A researcher may find paradoxes in practices and ideas and ask for clarification, or recognize that social dynamics and behavior are peculiar to group members present in a specific setting. This article highlights the usefulness of intentional variability and flexibility in the field. Researchers should plan to do multi-site analysis (MSA) to look for negative cases and opportunities to challenge commonsense notions. Additionally, this article emphasizes that the relationships built during fieldwork shape the data that are captured. Therefore, researchers need to consider the bases for their relationships, including what the subjects get out of them, and how subjects’ positionality affects what comes to be known. This perspective de-emphasizes false norms of objectivity and renders a more complete account of the social worlds we study.


2021 ◽  
Vol 17 (12) ◽  
pp. e1009681
Author(s):  
Michiel W. H. Remme ◽  
Urs Bergmann ◽  
Denis Alevi ◽  
Susanne Schreiber ◽  
Henning Sprekeler ◽  
...  

Systems memory consolidation involves the transfer of memories across brain regions and the transformation of memory content. For example, declarative memories that transiently depend on the hippocampal formation are transformed into long-term memory traces in neocortical networks, and procedural memories are transformed within cortico-striatal networks. These consolidation processes are thought to rely on replay and repetition of recently acquired memories, but the cellular and network mechanisms that mediate the changes of memories are poorly understood. Here, we suggest that systems memory consolidation could arise from Hebbian plasticity in networks with parallel synaptic pathways—two ubiquitous features of neural circuits in the brain. We explore this hypothesis in the context of hippocampus-dependent memories. Using computational models and mathematical analyses, we illustrate how memories are transferred across circuits and discuss why their representations could change. The analyses suggest that Hebbian plasticity mediates consolidation by transferring a linear approximation of a previously acquired memory into a parallel pathway. Our modelling results are further in quantitative agreement with lesion studies in rodents. Moreover, a hierarchical iteration of the mechanism yields power-law forgetting—as observed in psychophysical studies in humans. The predicted circuit mechanism thus bridges spatial scales from single cells to cortical areas and time scales from milliseconds to years.


2020 ◽  
Author(s):  
Sara Ruth Westbrook ◽  
Lauren Carrica ◽  
Asia Banks ◽  
Joshua Michael Gulley

Adolescent use of amphetamine and its closely related, methylated version methamphetamine, is alarmingly high in those who use drugs for nonmedical purposes. This raises serious concerns about the potential for this drug use to have a long-lasting, detrimental impact on the normal development of the brain and behavior that is ongoing during adolescence. In this review, we explore recent findings from both human and laboratory animal studies that investigate the consequences of amphetamine and methamphetamine exposure during this stage of life. We highlight studies that assess sex differences in adolescence, as well as those that are designed specifically to address the potential unique effects of adolescent exposure by including groups at other life stages (typically young adulthood). We consider epidemiological studies on age and sex as vulnerability factors for developing problems with the use of amphetamines, as well as human and animal laboratory studies that tap into age differences in use, its short-term effects on behavior, and the long-lasting consequences of this exposure on cognition. We also focus on studies of drug effects in the prefrontal cortex, which is known to be critically important for cognition and is among the later maturing brain regions. Finally, we discuss important issues that should be addressed in future studies so that the field can further our understanding of the mechanisms underlying adolescent use of amphetamines and its outcomes on the developing brain and behavior.


Author(s):  
Jochem van Kempen ◽  
Marc A. Gieselmann ◽  
Michael Boyd ◽  
Nicholas A. Steinmetz ◽  
Tirin Moore ◽  
...  

AbstractSpontaneous fluctuations in cortical excitability influence sensory processing and behavior. These fluctuations, long known to reflect global changes in cortical state, were recently found to be modulated locally within a retinotopic map during spatially selective attention. We found that periods of vigorous (On) and faint (Off) spiking activity, the signature of cortical state fluctuations, were coordinated across brain areas along the visual hierarchy and tightly coupled to their retinotopic alignment. During top-down attention, this interareal coordination was enhanced and progressed along the reverse cortical hierarchy. The extent of local state coordination between areas was predictive of behavioral performance. Our results show that cortical state dynamics are shared across brain regions, modulated by cognitive demands and relevant for behavior.One Sentence SummaryInterareal coordination of local cortical state is retinotopically precise and progresses in a reverse hierarchical manner during selective attention.


Sign in / Sign up

Export Citation Format

Share Document