Practical action levels for chelation therapy in plutonium inhalation using nose swab

2007 ◽  
Vol 127 (1-4) ◽  
pp. 411-414 ◽  
Author(s):  
O. Kurihara ◽  
C. Takada ◽  
K. Takasaki ◽  
K. Ito ◽  
T. Momose ◽  
...  
Keyword(s):  
Chelation Therapy ◽  
Practical Action ◽  
Action Levels

Thinking globally and locally: Increasing cooperation by matching construal to action levels in social dilemmas

2011 ◽  
Author(s):  
Kristjen B. Lundberg ◽  
Lawrence J. Sanna ◽  
Craig D. Parks ◽  
Edward C. Chang
Keyword(s):  
Social Dilemmas ◽  
Action Levels

Social Design for Services Framework

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Melanie SARANTOU ◽  
Satu MIETTINEN
Keyword(s):  
South Africa ◽  
Sustainable Development ◽  
Research Group ◽  
Design Research ◽  
Service Design ◽  
Social Design ◽  
Practical Action ◽  
The Social ◽  
The World

This paper addresses the fields of social and service design in development contexts, practice-based and constructive design research. A framework for social design for services will be explored through the survey of existing literature, specifically by drawing on eight doctoral theses that were produced by the World Design research group. The work of World Design researcher-designers was guided by a strong ethos of social and service design for development in marginalised communities. The paper also draws on a case study in Namibia and South Africa titled ‘My Dream World’. This case study presents a good example of how the social design for services framework functions in practice during experimentation and research in the field. The social design for services framework transfers the World Design group’s research results into practical action, providing a tool for the facilitation of design and research processes for sustainable development in marginal contexts.

Racism revisited with a new approach

2019 ◽  
Vol 1 (1) ◽  
pp. 13-20
Author(s):  
Yann A. Meunier
Keyword(s):  
Mental Disorder ◽  
Action Plans ◽  
New Approach ◽  
Practical Action ◽  
Root Cause ◽  
Transmissible Disease

Racism is a scourge which has plagued societies for centuries. Its root cause can be found in the fear of others. Some authors have considered it as a mental disorder in its more severe forms. We approach it from a novel and highly actionable angle by comparing it to a transmissible disease, candidiasis, with which racism holds many essential similarities that we outline in details. We also suggest various ways to eradicate and mitigate racism through practical action plans.

Living with water: at the cross-roads of change

1995 ◽  
Vol 31 (8) ◽  
pp. 393-400 ◽  
Author(s):  
Joost de Jong ◽  
Peter T. J. C. van Rooy ◽  
S. Harry Hosper
Keyword(s):  
Water Management ◽  
Water Quality ◽  
Water Environment ◽  
Integrated Water Management ◽  
Practical Action ◽  
The People ◽  
Global Perception ◽  
Local Water ◽  
Water Quality Deterioration ◽  
The Way

Until the last two decades, the global perception of how to control our various water bodies was remarkably similar – water management was organised on a sectoral basis, as it always had been. It was only in the 1970s that the people actually responsible for implementing water management began to become aware of the serious implications of such an approach: water quality deterioration, desiccation and an alarming loss of the flora and fauna that characterised their local water environment. It was a growing awareness that led to the formation of the concept of integrated water management, a concept almost universally accepted today as the way forward. However, despite the fact that few dispute the validity of the concept, a number of obstacles remain before this theoretical agreement can be transformed into practical action. Three main bottlenecks stand in the way of implementation: institutional, communicational and socio-political. Whilst solutions to these are available, the key question still to be answered is whether society is really prepared to accept the consequent changes in the way we live that will result from putting the theory of integrated water management into practice. It was this issue that dominated the “Living with water” conference held in Amsterdam in September 1994. The following is a summary of the discussions held there and the various papers that were submitted.

Therapeutic Macromolecular Iron Chelators

2019 ◽  
Vol 26 (2) ◽  
pp. 323-334 ◽  
Author(s):  
Upendra Bulbake ◽  
Alka Singh ◽  
Abraham J. Domb ◽  
Wahid Khan
Keyword(s):  
Iron Overload ◽  
Chelation Therapy ◽  
Iron Chelator ◽  
Therapeutic Agents ◽  
Iron Chelators ◽  
Low Molecular Weight ◽  
Research Findings ◽  
Pharmaceutical Properties ◽  
Single Living ◽  
Living Process

Iron is a key element for every single living process. On a fundamental level, targeting iron is a valuable approach for the treatment of disorders caused by iron overload. Utilizing iron chelators as therapeutic agents has received expanding consideration in chelation therapy. Approved low molecular weight (MW) iron chelators to treat iron overload may experience short half-lives and toxicities prompting moderately high adverse effects. In recent years, polymeric/macromolecular iron chelators have received attention as therapeutic agents. Polymeric iron chelators show unique pharmaceutical properties that are different to their conventional small molecule counterparts. These polymeric iron chelators possess longer plasma half-lives and reduced toxicities, thus exhibiting a significant supplement to currently using low MW iron chelator therapy. In this review, we have briefly discussed polymeric iron chelators and factors to be considered when designing clinically valuable iron chelators. We have also discussed applications of polymeric iron chelators in the diseases caused by iron overload associated with transfusional hemosiderosis, neurodegenerative disorders, malaria and cancer. With this, research findings for new polymeric iron chelators are also covered.

A Bridge Too Far?

2018 ◽  
Author(s):  
Charlotte P. Lee ◽  
Kjeld Schmidt
Keyword(s):  
Information Systems ◽  
Science And Technology Studies ◽  
Large Scale ◽  
Cooperative Work ◽  
Computer Supported Cooperative Work ◽  
Practical Action ◽  
Systems Research ◽  
Information Infrastructures ◽  
Information Systems Research ◽  
Critical Investigation

The study of computing infrastructures has grown significantly due to the rapid proliferation and ubiquity of large-scale IT-based installations. At the same time, recognition has also grown of the usefulness of such studies as a means for understanding computing infrastructures as material complements of practical action. Subsequently the concept of “infrastructure” (or “information infrastructures,” “cyberinfrastructures,” and “infrastructuring”) has gained increasing importance in the area of Computer-Supported Cooperative Work (CSCW) as well as in neighboring areas such as Information Systems research (IS) and Science and Technology Studies (STS). However, as such studies have unfolded, the very concept of “infrastructure” is being applied in different discourses, for different purposes, in myriad different senses. Consequently, the concept of “infrastructure” has become increasingly muddled and needs clarification. The chapter presents a critical investigation of the vicissitudes of the concept of “infrastructure” over the last 35 years.

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