scholarly journals A high-strength mineralized collagen bone scaffold for large-sized cranial bone defect repair in sheep

2018 ◽  
Vol 5 (5) ◽  
pp. 283-292 ◽  
Author(s):  
Shuo Wang ◽  
Zhijun Zhao ◽  
Yongdong Yang ◽  
Antonios G Mikos ◽  
Zhiye Qiu ◽  
...  
Keyword(s):  
Bone Defect ◽  
High Strength ◽  
Cranial Bone ◽  
Bone Scaffold ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Mineralized Collagen

scholarly journals Porous Poly(ε-caprolactone)–Poly(l-lactic acid) Semi-Interpenetrating Networks as Superior, Defect-Specific Scaffolds with Potential for Cranial Bone Defect Repair

2017 ◽  
Vol 18 (12) ◽  
pp. 4075-4083 ◽  
Author(s):  
Lindsay N. Woodard ◽  
Kevin T. Kmetz ◽  
Abigail A. Roth ◽  
Vanessa M. Page ◽  
Melissa A. Grunlan
Keyword(s):  
Lactic Acid ◽  
Bone Defect ◽  
Cranial Bone ◽  
Interpenetrating Networks ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Porous Poly

scholarly journals Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair

2019 ◽  
Vol 11 (37) ◽  
pp. 33548-33558 ◽  
Author(s):  
Kevin Schilling ◽  
Mirna El Khatib ◽  
Shane Plunkett ◽  
Jiajia Xue ◽  
Younan Xia ◽  
...  
Keyword(s):  
High Resolution ◽  
Oxygen Tension ◽  
Bone Defect ◽  
Electrospun Fiber ◽  
Cranial Bone ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Fiber Mesh

scholarly journals Spatiotemporal Analyses of Osteogenesis and Angiogenesis via Intravital Imaging in Cranial Bone Defect Repair

2015 ◽  
Vol 30 (7) ◽  
pp. 1217-1230 ◽  
Author(s):  
Chunlan Huang ◽  
Vincent P Ness ◽  
Xiaochuan Yang ◽  
Hongli Chen ◽  
Jiebo Luo ◽  
...  
Keyword(s):  
Bone Defect ◽  
Intravital Imaging ◽  
Cranial Bone ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Spatiotemporal Analyses

scholarly journals Bone defect repair on the alveolar wall of the maxillary sinus using collagen membranes and temporal fascia: an experimental study in monkeys

2011 ◽  
Vol 77 (4) ◽  
pp. 439-446 ◽  
Author(s):  
Adalberto Novaes Silva ◽  
José Américo de Oliveira ◽  
Maria Célia Jamur ◽  
José Ari Gualberto Junqueira ◽  
Vani Maria Correa ◽  
...  
Keyword(s):  
Experimental Study ◽  
Maxillary Sinus ◽  
Bone Defect ◽  
Alveolar Wall ◽  
Bone Defect Repair ◽  
Temporal Fascia ◽  
Defect Repair ◽  
Collagen Membranes

Clay-based nanocomposite hydrogel with attractive mechanical properties and sustained bioactive ion release for bone defect repair

2021 ◽  
Author(s):  
Xinyun Zhai ◽  
Changshun Ruan ◽  
Jie Shen ◽  
Chuping Zheng ◽  
Xiaoli Zhao ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Defect ◽  
Nanocomposite Hydrogel ◽  
Ion Release ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Gradual Release

Using nanoclay as the physical crosslinker, a novel clay-based nanocomposite hydrogel with attractive mechanical properties has be obtained, and the gradual release of intrinsic Mg2+ and Si4+ endows the system with excellent osteogenesis.

Injectable gel graft for bone defect repair

2014 ◽  
Vol 9 (1) ◽  
pp. 41-51 ◽  
Author(s):  
Josephine Fang ◽  
Zhi Yang ◽  
ShihJye Tan ◽  
Charisse Tayag ◽  
Marcel E Nimni ◽  
...  
Keyword(s):  
Bone Defect ◽  
Bone Defect Repair ◽  
Defect Repair

Nano-Hydroxyapatite Scaffold Based on Recombinant Human Bone Morphogenetic Protein 2 and Its Application in Bone Defect Repair

2021 ◽  
Vol 17 (7) ◽  
pp. 1330-1338
Author(s):  
Shibai Zhu ◽  
Xiaotian Zhang ◽  
Xi Chen ◽  
Yiou Wang ◽  
Shanni Li ◽  
...  
Keyword(s):  
Bone Defect ◽  
Bone Defects ◽  
Bone Morphogenetic Protein 2 ◽  
Artificial Bone ◽  
Bone Defect Repair ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Defect Repair ◽  
Hydroxyapatite Scaffold ◽  
Recombinant Human Bone

The best way in which to prepare scaffolds with good biological properties is an urgent problem in the field of tissue engineering. In this paper we discuss the preparation of nano-hydroxyapatite scaffold of recombinant human bone morphogenetic protein-2 (rhBMP-2) and its application in bone defect repair. rhBMP-2 reagent was dissolved in 1 mol/L sodium dihydrogen phosphate solution, and the rhBMP-2 solution was added to the nano-hydroxyapatite artificial bone with a 100 μL glass micro dropper at the rate of 10 drops/min to obtain Nano-HA/rhBMP-2 composite artificial bone. In in vivo experiments, rabbits were fixed on an operating table, a 2 cm longitudinal incision was made in the middle part of the radial forearm, and the radius was cut with a wire saw and periosteum, 2.5 cm away from the distal radius. After washing the wound with normal saline, Adv-hBMP-2/MC3T3-E1 nano-HA composite artificial bone, MC3T3-E1 nan-HA composite artificial bone, or Nano-HA artificial bone were implanted in different groups. The artificial bone scaffold prepared in this study has a stronger ability to repair bone defects than the alternatives, and is a promising prospect for the clinical treatment of bone defects.

Local Elimination of Senescent Cells Promotes Bone Defect Repair during Aging

2022 ◽  
Author(s):  
Xiaotao Xing ◽  
Haisen Huang ◽  
Xin Gao ◽  
Jian Yang ◽  
Qi Tang ◽  
...  
Keyword(s):  
Bone Defect ◽  
Bone Defect Repair ◽  
Defect Repair
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