scholarly journals Characterization and evaluation of a femtosecond laser-induced osseointegration and an anti-inflammatory structure generated on a titanium alloy

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Yang Liu ◽  
Zhongying Rui ◽  
Wei Cheng ◽  
Licheng Song ◽  
Yunqiang Xu ◽  
...  
Keyword(s):  
Titanium Alloy ◽  
Femtosecond Laser ◽  
Surface Properties ◽  
Cellular Response ◽  
Titanium Surface ◽  
Macrophage Polarization ◽  
Ti Alloy ◽  
Bone Implant ◽  
Cell Material Interactions ◽  
Factor Secretion

Abstract Cell–material interactions during early osseointegration of the bone–implant interface are critical and involve crosstalk between osteoblasts and osteoclasts. The surface properties of titanium implants also play a critical role in cell–material interactions. In this study, femtosecond laser treatment and sandblasting were used to alter the surface morphology, roughness and wettability of a titanium alloy. Osteoblasts and osteoclasts were then cultured on the resulting titanium alloy disks. Four disk groups were tested: a polished titanium alloy (pTi) control; a hydrophilic micro-dislocation titanium alloy (sandblasted Ti (STi)); a hydrophobic nano-mastoid Ti alloy (femtosecond laser-treated Ti (FTi)); and a hydrophilic hierarchical hybrid micro-/nanostructured Ti alloy [femtosecond laser-treated and sandblasted Ti (FSTi)]. The titanium surface treated by the femtosecond laser and sandblasting showed higher biomineralization activity and lower cytotoxicity in simulated body fluid and lactate dehydrogenase assays. Compared to the control surface, the multifunctional titanium surface induced a better cellular response in terms of proliferation, differentiation, mineralization and collagen secretion. Further investigation of macrophage polarization revealed that increased anti-inflammatory factor secretion and decreased proinflammatory factor secretion occurred in the early response of macrophages. Based on the above results, the synergistic effect of the surface properties produced an excellent cellular response at the bone–implant interface, which was mainly reflected by the promotion of early ossteointegration and macrophage polarization.

Femtosecond laser induced fixation of calcium alkali phosphate ceramics on titanium alloy bone implant material

2010 ◽  
Vol 6 (8) ◽  
pp. 3318-3324 ◽  
Author(s):  
Christian Symietz ◽  
Erhard Lehmann ◽  
Renate Gildenhaar ◽  
Jörg Krüger ◽  
Georg Berger
Keyword(s):  
Titanium Alloy ◽  
Femtosecond Laser ◽  
Bone Implant ◽  
Implant Material

Effects of storage methods on time-related changes of titanium surface properties and cellular response

2012 ◽  
Vol 7 (5) ◽  
pp. 055002 ◽  
Author(s):  
Haibin Lu ◽  
Lei Zhou ◽  
Lei Wan ◽  
Shaobing Li ◽  
Mingdeng Rong ◽  
...  
Keyword(s):  
Surface Properties ◽  
Cellular Response ◽  
Titanium Surface ◽  
Storage Methods

Effect of titanium surface properties on electrochemically induced biomineralization

2010 ◽  
Author(s):  
F. Sermin Utku ◽  
Eren Seckin ◽  
Gultekin Goller ◽  
Candan Tamerler ◽  
Mustafa Urgen
Keyword(s):  
Surface Properties ◽  
Titanium Surface

scholarly journals Titanium oral implants: surface characteristics, interface biology and clinical outcome

2010 ◽  
Vol 7 (suppl_5) ◽  
Author(s):  
Anders Palmquist ◽  
Omar M. Omar ◽  
Marco Esposito ◽  
Jukka Lausmaa ◽  
Peter Thomsen
Keyword(s):  
Surface Properties ◽  
Cellular Response ◽  
Randomized Clinical Trials ◽  
Three Dimensional ◽  
Cell Communication ◽  
Surface Characteristics ◽  
Titanium Implants ◽  
Material Surface ◽  
Oral Implants

Bone-anchored titanium implants have revolutionized oral healthcare. Surface properties of oral titanium implants play decisive roles for molecular interactions, cellular response and bone regeneration. Nevertheless, the role of specific surface properties, such as chemical and phase composition and nanoscale features, for the biological in vivo performance remains to be established. Partly, this is due to limited transfer of state-of-the-art preparation techniques to complex three-dimensional geometries, analytical tools and access to minute, intact interfacial layers. As judged by the available results of a few randomized clinical trials, there is no evidence that any particular type of oral implant has superior long-term success. Important insights into the recruitment of mesenchymal stem cells, cell–cell communication at the interface and high-resolution imaging of the interface between the surface oxide and the biological host are prerequisites for the understanding of the mechanisms of osseointegration. Strategies for development of the next generation of material surface modifications for compromised tissue are likely to include time and functionally programmed properties, pharmacological modulation and incorporation of cellular components.

Sub-100 nanometer transverse gratings written by femtosecond laser pulses on a titanium surface

2013 ◽  
Vol 10 (5) ◽  
pp. 056004 ◽  
Author(s):  
Andrey A Ionin ◽  
Sergey I Kudryashov ◽  
Sergey V Makarov ◽  
Leonid V Seleznev ◽  
Dmitry V Sinitsyn ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Titanium Surface ◽  
Laser Pulses ◽  
Femtosecond Laser Pulses

The Coating of Bovine-Source Hydroxyapatite on Titanium Alloy (Ti-6Al-4V ELI) Using Electrophoretic Deposition for Biomedical Application

2020 ◽  
Vol 1000 ◽  
pp. 97-106
Author(s):  
Dian Juliadmi ◽  
Nuzul Ficky Nuswantoro ◽  
Hidayatul Fajri ◽  
Irma Yulia Indriyani ◽  
Jon Affi ◽  
...  
Keyword(s):  
Particle Size ◽  
Titanium Alloy ◽  
Electrophoretic Deposition ◽  
Bone Growth ◽  
Biomedical Application ◽  
Size Variation ◽  
Bone Implant ◽  
Bioactive Substance ◽  
Good Coating ◽  
Bone Apatite

Research about the utilization of titanium alloy (Ti-6Al-4V ELI) as implant material in the treatment of orthopedic cases had been increasing. Health problems appear due to the drawbacks of using titanium. The lack of titanium using is bio-inertness characteristic, which decreasing its bioactivity and results in low bone growth and effect for implant failure. The titanium can be modified with coating on the surface using a bioactive substance that is natural-source hydroxyapatite. Bovine-source hydroxyapatite (bovineHA) contains apatite component that is similar to human bone apatite. The coating process was carried out using particle size variation (25 μm, 63 μm, and 125 μm) of bovineHA. The electrophoretic deposition (EPD) method was applied to coat hydroxyapatite with 10 volt for 5 minutes onto the titanium surface. The result showed that different size particles have an effect on coating properties. The coating composed by particle-sized 25 μm has better surface coverage (95.89%), indicating more particle mass (particle weight 6.97x103 μg) attached to surface material, thus resulting thick coating. The good coating characteristic using bovine-source hydroxyapatite with small particle size was expected can be used in biomedical applications due to fulfill the prerequisite of the bone implant.

scholarly journals The Kinetics Of Ti-1Al-1Mn Alloy Thermal Oxidation And Charcteristic Of Oxide Layer

2015 ◽  
Vol 60 (2) ◽  
pp. 735-738 ◽  
Author(s):  
D. Klimecka-Tatar ◽  
S. Borkowski ◽  
P. Sygut
Keyword(s):  
Titanium Alloy ◽  
Artificial Saliva ◽  
Electrochemical Corrosion ◽  
Mass Gain ◽  
Ti Alloy ◽  
Metallic Materials ◽  
Cyclic Annealing ◽  
Air Atmosphere ◽  
Kinetic Oxidation ◽  
Kinetics Of

Abstract The main goal of the study was to carry out the treatment of cyclic oxidation of Ti alloy (Ti-1Al-1Mn) in air atmosphere. Based on measurements of mass gain of titanium alloy samples (Ti-1Al-1Mn) the kinetic oxidation curves during cyclic annealing were determined. The oxidized surface of the titanium alloy was carefully observed with optical microscopy equipment and the geometrical development, shape and surface morphology were defined. The phase composition of the obtained oxide layers on the Ti-alloy with qualitative analysis of the X-ray were defined. Since titanium alloys are among the most widely used metallic materials in dental prosthetics the corrosion measurements in a solution simulating the environment of the oral cavity were carried out. The results confirmed that the used titanium alloy easily covered with oxides layers, which to some extent inhibit the processes of electrochemical corrosion in artificial saliva solution.

scholarly journals Titanium surface modification using femtosecond laser with 1013–1015 W/cm2 intensity in vacuum

2012 ◽  
Vol 31 (1) ◽  
pp. 29-36 ◽  
Author(s):  
M. Trtica ◽  
D. Batani ◽  
R. Redaelli ◽  
J. Limpouch ◽  
V. Kmetik ◽  
...  
Keyword(s):  
Surface Modification ◽  
Femtosecond Laser ◽  
Titanium Surface ◽  
Femtosecond Lasers ◽  
Single Pulse ◽  
Surface Structures ◽  
Pulse Regime ◽  
Periodic Surface ◽  
Reduced Intensity ◽  
Surface Changes

AbstractThe response of titanium surface irradiated with high intensity (1013 – 1015 W/cm2) Ti:sapphire laser was studied in vacuum. Most of the reported investigations were conducted with nano- to femtosecond lasers in gas atmospheres while the studies of titanium surface interacting with femtosecond laser in vacuum are scarce. The laser employed in our experiment was operating at 800 nm wavelength and pulse duration of 60 fs in single pulse regime. The observed surface changes and phenomena are (1) creation of craters, (2) formation of periodic surface structures at the reduced intensity, and (3) occurrence of plasma in front the target. Since microstructuring of titanium is very interesting in many areas (industry, medicine), it can be concluded from this study that the reported laser intensities can effectively be applied for micromachining of the titanium surface (increasing the roughness, formation of parallel periodic surface structures etc.).

Comparative Study of Surface Contaminated Layer on Titanium Aluminum Alloy and Titanium Alloy Investment Castings

2021 ◽  
Vol 1035 ◽  
pp. 602-607
Author(s):  
Zhi Hua Feng ◽  
Xian Fei Ding ◽  
Xin Feng ◽  
Hai Nan ◽  
Ai Bin Zhang
Keyword(s):  
Titanium Alloy ◽  
Aluminum Alloy ◽  
Comparative Study ◽  
Chemical Reaction ◽  
Microhardness Measurement ◽  
Ceramic Mold ◽  
Al Alloy ◽  
Ti Alloy ◽  
Titanium Aluminum ◽  
Alloy Castings

A comparative study of the surface contaminated layer formed by chemical reaction between ceramic-mold and titanium aluminum alloy castings or titanium alloy castings were carried out. The morphology, thickness and hardness of the surface contaminated layer were characterized by means of metalloscopy and microhardness measurement. The results show that surface contaminated layers formed between Ti-Al alloy castings and ceramic-mold, also formed between Ti alloy castings and ceramic-mold. The surface contaminated layers of Ti-Al alloy castings were continuous and compact, their thickness was about 0~90 μm. The surface contaminated layers of titanium alloy castings were not even, their thickness was 0~900 μm. Titanium alloy is more liable to react with the ceramic -mold than the Ti-Al alloy.

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