scholarly journals Factors associated with fatigue in hip and/or knee osteoarthritis: a systematic review and best evidence synthesis

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Henrietta O Fawole ◽  
Opeyemi A Idowu ◽  
Ukachukwu O Abaraogu ◽  
Andrea Dell’Isola ◽  
Jody L Riskowski ◽  
...  
Keyword(s):  
Physical Activity ◽  
Depressive Symptoms ◽  
Physical Function ◽  
Longitudinal Studies ◽  
Evidence Synthesis ◽  
Current Evidence ◽  
Activity Levels ◽  
Knee Oa ◽  
Best Evidence Synthesis ◽  
Physical Activity Levels

Abstract Objective The aim was systematically to identify and evaluate factors related to fatigue in individuals with hip and/or knee OA. Methods A systematic literature search was conducted using AMED, CINAHL, MEDLINE, ProQuest and Web of Science Core Collections databases. Inclusion criteria comprised cross-sectional, case–control or longitudinal studies on patients with a diagnosis of hip and/or knee OA that included self-reported fatigue measures. Study quality was assessed using the National Heart, Lung and Blood Institute quality appraisal tool, and factors were synthesized within a bio-behavioural framework. Study designs and quality were combined to determine current evidence levels using best evidence synthesis grading. The full review protocol is available from PROSPERO (PROSPERO 2019: CRD42019138571). Results Twenty-four studies were included, of which 19 were high, 4 moderate and 1 low quality. There was strong evidence of an association between poor self-reported physical function and high depressive symptoms with higher fatigue. Moderate evidence of an association was found between severe pain, high numbers of co-morbidities and low physical activity levels with higher fatigue. There was moderate or limited evidence of no association between most sociodemographic factors and radiographic OA severity with fatigue. Conclusion Targets for fatigue management might include improving physical function, reducing depressive symptoms, pain and co-morbidities, and increasing physical activity levels. There is a need for more rigorous longitudinal studies to understand the causal effect of fatigue determinants within the hip and knee OA populations.

scholarly journals P127 Factors associated with self-reported fatigue in hip and/or knee osteoarthritis: a systematic review

Rheumatology ◽  
2020 ◽  
Vol 59 (Supplement_2) ◽  
Author(s):  
Henrietta O Fawole ◽  
Opeyemi A Idowu ◽  
Ukachukwu O Abaraogu ◽  
Jody L Riskowski ◽  
Andrea Dell'Isola ◽  
...  
Keyword(s):  
Systematic Review ◽  
Depressive Symptoms ◽  
Knee Osteoarthritis ◽  
Physical Function ◽  
Longitudinal Studies ◽  
Evidence Synthesis ◽  
Cross Sectional ◽  
Factors Associated ◽  
Knee Oa ◽  
Best Evidence Synthesis

Abstract Background Fatigue is an important, under-researched and poorly understood symptom among hip and/or knee osteoarthritis (OA) populations. To devise the best fatigue management strategy in these populations, it is necessary to evaluate the evidence on risk factors for fatigue. This study aimed to give an overview and evaluate the evidence on the factors associated with fatigue in hip and/or knee OA populations. Methods We conducted a systematic review using MEDLINE, AMED, CINAHL, ProQuest, and Web of Science Core Collections databases from inception to June 2019. Inclusion criteria comprised cross-sectional and longitudinal studies on patients with a diagnosis of hip and/or knee OA, included a measure of self-reported fatigue and studies that performed a subgroup analysis of hip/knee OA from other included populations. Two reviewers simultaneously screened articles for eligibility and extracted the following data: study design, fatigue outcome tool, follow-up time and association between factors and fatigue. The methodological quality of the included studies was assessed using the National Heart, Lung and Blood Institute quality appraisal tool. Study quality and study designs were combined to determine the level of evidence using best-evidence synthesis, which comprised six levels of evidence (Table 1). Results Eighteen studies (10 cross-sectional designs, 8 longitudinal designs) were included. A majority of the studies included were of good quality, whilst two had fair quality and one poor quality. Lower physical function, more pain, higher depressive symptoms, lower physical activity, older age, increased anxiety, greater pain catastrophizing, worse radiographic evidence, higher body mass index, greater comorbidity/illness burden, lower six minutes walk and increased joint stiffness were included in the best evidence synthesis. From the best evidence grading, most of these factors had limited or conflicting evidence on its association with fatigue within the hip/knee OA populations. However, lower physical function and higher depressive symptoms were graded as having strong evidence on their associations with fatigue while higher pain levels had moderate evidence. Conclusion Lower physical function levels, higher depressive symptoms and higher pain are related to fatigue in the hip/knee OA population. More longitudinal studies are warranted to investigate the potential association of other identified factors and fatigue. Disclosures H.O. Fawole None. O.A. Idowu None. U.O. Abaraogu None. J.L. Riskowski None. A. Dell'Isola None. M.P. Steultjens None. S.F.M. Chastin None.

scholarly journals Does Cardiac Rehabilitation After an Acute Cardiac Syndrome Lead to Changes in Physical Activity Habits? Systematic Review

2015 ◽  
Vol 95 (2) ◽  
pp. 167-179 ◽  
Author(s):  
Nienke ter Hoeve ◽  
Bionka M.A. Huisstede ◽  
Henk J. Stam ◽  
Ron T. van Domburg ◽  
Madoka Sunamura ◽  
...  
Keyword(s):  
Physical Activity ◽  
Randomized Clinical Trials ◽  
Evidence Synthesis ◽  
Activity Levels ◽  
Long Term Effects ◽  
Short Term ◽  
Home Based ◽  
Best Evidence Synthesis ◽  
Physical Activity Levels

BackgroundOptimal physical activity levels have health benefits for patients with acute coronary syndrome (ACS) and are an important goal of cardiac rehabilitation (CR).PurposeThe purpose of this study was to systematically review literature regarding short-term effects (<6 months after completion of CR) and long-term effects (≥6 months after completion) of standard CR on physical activity levels in patients with ACS.Data SourcesPubMed, EMBASE, CINAHL, and PEDro were systematically searched for relevant randomized clinical trials (RCTs) published from 1990 until 2012.Study SelectionRandomized clinical trials investigating CR for patients with ACS reporting physical activity level were reviewed.Data ExtractionTwo reviewers independently selected articles, extracted data, and assessed methodological quality. Results were summarized with a best evidence synthesis. Results were categorized as: (1) center-based/home-based CR versus no intervention, (2) comparison of different durations of CR, and (3) comparison of 2 types of CR.Data SynthesisA total of 26 RCTs were included. Compared with no intervention, there was, at most, conflicting evidence for center-based CR and moderate evidence for home-based CR for short-term effectiveness. Limited evidence and no evidence were found for long-term maintenance for center-based and home-based CR, respectively. When directly compared with center-based CR, moderate evidence showed that home-based CR has better long-term effects. There was no clear evidence that increasing training volume, extending duration of CR, or adding an extra intervention to CR is more effective.LimitationsBecause of the variety of CR interventions in the included RCTs and the variety of outcome measures in the included RCTs, pooling of data was not possible. Therefore, a best evidence synthesis was used.ConclusionsIt would appear that center-based CR is not sufficient to improve and maintain physical activity habits. Home-based programs might be more successful, but the literature on these programs is limited. More research on finding successful interventions to improve activity habits is needed.

scholarly journals Physical Activity in Rheumatoid Arthritis: A Systematic Review

2012 ◽  
Vol 9 (7) ◽  
pp. 1036-1048 ◽  
Author(s):  
Marie Tierney ◽  
Alexander Fraser ◽  
Norelee Kennedy
Keyword(s):  
Rheumatoid Arthritis ◽  
Physical Activity ◽  
Systematic Review ◽  
Population Group ◽  
Evidence Base ◽  
Current Evidence ◽  
Activity Levels ◽  
Current Evidence Base ◽  
Physical Activity Levels ◽  
Methodological Considerations

Background:Physical activity is associated with improved health outcomes in many populations. It is assumed that physical activity levels in the rheumatoid arthritis (RA) population may be reduced as a result of symptoms of the disease. The objective of this review is to establish the current evidence base for levels of physical activity in the RA population.Methods:A systematic review was performed of 7 databases (Ema-base, MEDLINE, AMED, Biomedical Reference Collection Expanded, CINAHL, Nursing and Allied Health Collection, and SportsDiscus) up to February 2011 to examine the evidence in the area.Results:One hundred and thirty-six studies were identified through electronic searching. One hundred and six were excluded based on title and/or abstract analysis and a further 14 were excluded based on full text analysis. Sixteen studies meeting the criteria were deemed suitable for inclusion. The results of the included studies indicate that the level of physical activity may be lower among individuals with RA when compared with healthy controls or normative data.Conclusions:There are a number of methodological considerations at play within the studies reviewed which prohibits definitive conclusion on the physical activity levels of this population group. Given the known health benefits of physical activity, further research in this area appears indicated.

scholarly journals Trajectories of frailty, physical function, and physical activity levels in elderly patients with heart failure

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Michitaka Kato ◽  
Shintaro Ono ◽  
Hiromasa Seko ◽  
Toshiya Tsukamoto ◽  
Yasunari Kurita ◽  
...  
Keyword(s):  
Physical Activity ◽  
Heart Failure ◽  
Elderly Patients ◽  
Physical Function ◽  
Activity Levels ◽  
Patients With Heart Failure ◽  
Physical Activity Levels

scholarly journals Home Confinement in Previously Active Older Adults: A Cross-Sectional Analysis of Physical Fitness and Physical Activity Behavior and Their Relationship With Depressive Symptoms

2021 ◽  
Vol 12 ◽  
Author(s):  
Joana Carvalho ◽  
Flávia Borges-Machado ◽  
Andreia N. Pizarro ◽  
Lucimere Bohn ◽  
Duarte Barros
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Depressive Symptoms ◽  
Physical Fitness ◽  
Exercise Program ◽  
Sitting Time ◽  
Activity Levels ◽  
Cross Sectional ◽  
Depressed Group ◽  
Physical Activity Levels

AimThe aim of our study was to analyze physical activity levels, sitting time, physical fitness, and their relationship with depressive symptoms after home confinement in previously active older adults.MethodsThis cross-sectional study sample comprised 68 older adults (74.24 ± 5.67 years) from a community-based exercise program conducted in Porto, Portugal. After home confinement, participants were assessed in person for lower-body strength (30-s chair stand test), cardiorespiratory fitness (6-min walking test), agility/dynamic balance (8-ft up-and-go test), handgrip strength, and anthropometry. Telephone interviews were performed to evaluate depressive symptoms with the Geriatric Depression Scale – 15 items (GDS-15) and physical activity levels through the International Physical Activity Questionnaire (IPAQ-SV). Individuals were also asked to self-report changes in their physical activity levels and time spent sitting.ResultsNinety percent of older adults self-reported a decrease in overall physical activity levels, and nearly 65% increased daily sitting time during the home confinement. However, previously active older adults still presented high levels of physical fitness (scores above 50th compared with Portuguese normative values) after 11 weeks of home confinement. Overall, 52.9% of participants scored 5 or more points on GDS-15, which is suggestive of depression. Higher levels of moderate-to-vigorous physical activity (MVPA) and cardiorespiratory fitness were found in the non-depressed group compared with the depressed group. Finally, results from multiple regression analysis revealed that MVPA was negatively associated with depression. This model explained 16.4% of the variability seen in depression score, controlled for age, gender, and education.ConclusionEven reporting a decline in physical activity, older adults who previously participated in a formal exercise program, still presented high levels of physical fitness after 11 weeks of home confinement. However, MVPA, but not physical fitness, seems to be an associated depression score in previously active older adults. These results reinforce the importance of older adults to remain physically active, since higher levels of MVPA may have a protective effect on depressive symptoms and, therefore, mitigate the negative impact of home confinement on mental health. Future longitudinal research studies are needed to ascertain these results.

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