scholarly journals Assessing bone mineral density in vivo: dual energy X-ray absorptiometry

2004 ◽  
Vol 83 (2) ◽  
pp. 215-221 ◽  
Author(s):  
P.Y. Hester ◽  
M.A. Schreiweis ◽  
J.I. Orban ◽  
H. Mazzuco ◽  
M.N. Kopka ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray

scholarly journals Bone Mineral Densities and Mechanical Properties of Retrieved Femoral Bone Samples in relation to Bone Mineral Densities Measured in the Respective Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yvonne Haba ◽  
Ralf Skripitz ◽  
Tobias Lindner ◽  
Martin Köckerling ◽  
Andreas Fritsche ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Femoral Head ◽  
Bone Mineral ◽  
Hip Replacement ◽  
Dual Energy ◽  
Femoral Bone ◽  
Mineral Density ◽  
X Ray

The bone mineral density (BMD) of retrieved cancellous bone samples is compared to the BMD measuredin vivoin the respective osteoarthritic patients. Furthermore, mechanical properties, in terms of structural modulus (Es) and ultimate compression strength (σmax) of the bone samples, are correlated to BMD data. Human femoral heads were retrieved from 13 osteoarthritic patients undergoing total hip replacement. Subsequently, the BMD of each bone sample was analysed using dual energy X-ray absorptiometry (DXA) as well as ashing. Furthermore, BMDs of the proximal femur were analysed preoperatively in the respective patients by DXA. BMDs of the femoral neck and head showed a wide variation, from1016±166 mg/cm2to1376±404 mg/cm2. BMDs of the bone samples measured by DXA and ashing yielded values of315±199 mg/cm2and347±113 mg/cm3, respectively.Esandσmaxamounted to232±151 N/mm2and6.4±3.7 N/mm2. Significant correlation was found between the DXA and ashing data on the bone samples and the DXA data from the patients at the femoral head (r=0.85and 0.79, resp.).Escorrelated significantly with BMD in the patients and bone samples as well as the ashing data (r=0.79,r=0.82, andr=0.8, resp.).

Dual-energy X-ray absorptiometry underestimates in vivo lumbar spine bone mineral density in overweight rats

2017 ◽  
Vol 36 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Rim Cherif ◽  
Laurence Vico ◽  
Norbert Laroche ◽  
Mohsen Sakly ◽  
Nebil Attia ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Dual Energy ◽  
Spine Bone Mineral Density ◽  
Mineral Density ◽  
X Ray

Sequential and precise in vivo measurement of bone mineral density in rats using dual-energy x-ray absorptiometry

2009 ◽  
Vol 7 (3) ◽  
pp. 311-316 ◽  
Author(s):  
Patrick Ammann ◽  
René Rizzoli ◽  
Daniel Slosman ◽  
Jean-Philippe Bonjour
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
In Vivo Measurement

In vivo differences among scan modes in bone mineral density measurement at dual-energy X-ray absorptiometry

2013 ◽  
Vol 119 (4) ◽  
pp. 257-260 ◽  
Author(s):  
Michele Bandirali ◽  
Luca M. Sconfienza ◽  
Alberto Aliprandi ◽  
Giovanni Di Leo ◽  
Daniele Marchelli ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Density Measurement ◽  
Dual Energy ◽  
Bone Mineral Density Measurement ◽  
Mineral Density ◽  
X Ray ◽  
Scan Modes

scholarly journals POS0045 LEAST SIGNIFICANT CHANGE IN BONE DENSITOMETRY IN PATIENTS WITH OBESITY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 227.2-228
Author(s):  
D. Claire ◽  
M. Geoffroy ◽  
L. Kanagaratnam ◽  
C. Isabelle ◽  
A. Hittinger ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
General Population ◽  
Bone Mineral ◽  
Bone Densitometry ◽  
Dual Energy ◽  
Mineral Density ◽  
Least Significant Change ◽  
X Ray ◽  
Significant Change

Background:Dual energy X-ray absoprtiometry is the reference method to mesure bone mineral density (1). Loss of bone mineral density is significant if it exceeds the least significant change. The threshold value used in general population is 0,03 g/cm2 (2). Patients with obesity are known for having a higher bone mineral density due to metabolism and physiopathology characteristics (3,4).Objectives:The aim of our study was to determine the least significant change in bone densitometry in patients with obesity.Methods:We conducted an interventionnal study in 120 patients with obesity who performed a bone densitometry. We measured twice the bone mineral density at the lumbar spine, the femoral neck and the total hip in the same time (5,6). We determined the least significant change in bone densitometry from each pair of measurements, using the Bland and Altman method. We also determined the least significant change in bone densitometry according to each stage of obesity.Results:The least significant change in bone densitometry in patients with obesity is 0,046g/cm2 at the lumbar spine, 0.069 g/cm2 at the femoral neck and 0.06 g/cm2 at the total hip.Conclusion:The least significant change in bone densitometry in patients with obesity is higher than in general population. These results may improve DXA interpretation in this specific population, and may personnalize their medical care.References:[1]Lees B, Stevenson JC. An evaluation of dual-energy X-ray absorptiometry and comparison with dual-photon absorptiometry. Osteoporos Int. mai 1992;2(3):146-52.[2]Briot K, Roux C, Thomas T, Blain H, Buchon D, Chapurlat R, et al. Actualisation 2018 des recommandations françaises du traitement de l’ostéoporose post-ménopausique. Rev Rhum. oct 2018;85(5):428-40.[3]Shapses SA, Pop LC, Wang Y. Obesity is a concern for bone health with aging. Nutr Res N Y N. mars 2017;39:1-13.[4]Savvidis C, Tournis S, Dede AD. Obesity and bone metabolism. Hormones. juin 2018;17(2):205-17.[5]Roux C, Garnero P, Thomas T, Sabatier J-P, Orcel P, Audran M, et al. Recommendations for monitoring antiresorptive therapies in postmenopausal osteoporosis. Jt Bone Spine Rev Rhum. janv 2005;72(1):26-31.[6]Ravaud P, Reny JL, Giraudeau B, Porcher R, Dougados M, Roux C. Individual smallest detectable difference in bone mineral density measurements. J Bone Miner Res. août 1999;14(8):1449-56.Disclosure of Interests:None declared.

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