scholarly journals Effects of dietary levels of vitamin A on the egg yield and immune responses of laying hens

1998 ◽  
Vol 77 (4) ◽  
pp. 542-546 ◽  
Author(s):  
B Coskun ◽  
F Inal ◽  
I Celik ◽  
O Erganis ◽  
AM Tiftik ◽  
...  
Keyword(s):  
Vitamin A ◽  
Immune Responses ◽  
Laying Hens

scholarly journals Effect of Dietary Supplemental Levels of Vitamin A on the Egg Production and Immune Responses of Heat-Stressed Laying Hens

2002 ◽  
Vol 81 (4) ◽  
pp. 458-465 ◽  
Author(s):  
H. Lin ◽  
L.F. Wang ◽  
J.L. Song ◽  
Y.M. Xie ◽  
Q.M. Yang
Keyword(s):  
Vitamin A ◽  
Immune Responses ◽  
Egg Production ◽  
Laying Hens

scholarly journals Vitamin A or E and a catechin synergize as vaccine adjuvant to enhance immune responses in mice by induction of early interleukin-15 but not interleukin-1βresponses

Immunology ◽  
2016 ◽  
Vol 148 (4) ◽  
pp. 352-362 ◽  
Author(s):  
Sapna Patel ◽  
Archana Akalkotkar ◽  
Joseph J. Bivona ◽  
Ji-Young Lee ◽  
Young-Ki Park ◽  
...  
Keyword(s):  
Vitamin A ◽  
Immune Responses ◽  
Vaccine Adjuvant ◽  
Interleukin 15

scholarly journals Baseline Serum Vitamin A and D Levels Determine Benefit of Oral Vitamin A&D Supplements to Humoral Immune Responses Following Pediatric Influenza Vaccination

Viruses ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 907 ◽  
Author(s):  
Nehali Patel ◽  
Rhiannon R. Penkert ◽  
Bart G. Jones ◽  
Robert E. Sealy ◽  
Sherri L. Surman ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Vitamin A ◽  
Immune Responses ◽  
Vaccine Efficacy ◽  
Serum Vitamin ◽  
Controlled Study ◽  
Vitamin Supplement ◽  
Oral Vitamin ◽  
Baseline Serum ◽  
High Baseline

Maximizing vaccine efficacy is critical, but previous research has failed to provide a one-size-fits-all solution. Although vitamin A and vitamin D supplementation studies have been designed to improve vaccine efficacy, experimental results have been inconclusive. Information is urgently needed to explain study discrepancies and to provide guidance for the future use of vitamin supplements at the time of vaccination. We conducted a randomized, blinded, placebo-controlled study of influenza virus vaccination and vitamin supplementation among 2 to 8 (inclusive) year old children over three seasons, including 2015–2016 (n = 9), 2016–2017 (n = 44), and 2017–2018 (n = 26). Baseline measurements of vitamins A and D were obtained from all participants. Measurements were of serum retinol, retinol-binding protein (RBP, a surrogate for retinol), and 25-hydroxyvitamin D (25(OH)D). Participants were stratified into two groups based on high and low incoming levels of RBP. Children received two doses of the seasonal influenza virus vaccine on days 0 and 28, either with an oral vitamin supplement (termed A&D; 20,000 IU retinyl palmitate and 2000 IU cholecalciferol) or a matched placebo. Hemagglutination inhibition (HAI) antibody responses were evaluated toward all four components of the influenza virus vaccines on days 0, 28, and 56. Our primary data were from season 2016–2017, as enrollment was highest in this season and all children exhibited homogeneous and negative HAI responses toward the Phuket vaccine at study entry. Responses among children who entered the study with insufficient or deficient levels of RBP and 25(OH)D benefited from the A&D supplement (p < 0.001 for the day 28 Phuket response), whereas responses among children with replete levels of RBP and 25(OH)D at baseline were unaffected or weakened (p = 0.02 for the day 28 Phuket response). High baseline RBP levels associated with high HAI titers, particularly for children in the placebo group (baseline RBP correlated positively with Phuket HAI titers on day 28, r = 0.6, p = 0.003). In contrast, high baseline 25(OH)D levels associated with weak HAI titers, particularly for children in the A&D group (baseline 25(OH)D correlated negatively with Phuket HAI titers on day 28, r = −0.5, p = 0.02). Overall, our study demonstrates that vitamin A&D supplementation can improve immune responses to vaccines when children are vitamin A and D-insufficient at baseline. Results provide guidance for the appropriate use of vitamins A and D in future clinical vaccine studies.

scholarly journals Effect of Heat Stress on Production Parameters and Immune Responses of Commercial Laying Hens

2004 ◽  
Vol 83 (6) ◽  
pp. 889-894 ◽  
Author(s):  
M.M. Mashaly ◽  
G.L. Hendricks ◽  
M.A. Kalama ◽  
A.E. Gehad ◽  
A.O. Abbas ◽  
...  
Keyword(s):  
Heat Stress ◽  
Immune Responses ◽  
Laying Hens ◽  
Production Parameters

#643 Vitamin A status and in vitro immune responses in children with sickle cell disease

1996 ◽  
Vol 18 (4) ◽  
pp. 451
Author(s):  
S. Kuvihidila ◽  
D. Ode ◽  
L. Yu ◽  
R. Gardner ◽  
R. P. Warrier
Keyword(s):  
Sickle Cell Disease ◽  
Vitamin A ◽  
Immune Responses ◽  
Sickle Cell ◽  
Cell Disease ◽  
Vitamin A Status
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