Perceived Sensitivity to Pain and Responsiveness to Non-noxious Sensation in Substance Use Disorder

Pain Medicine ◽  
2019 ◽  
Vol 21 (9) ◽  
pp. 1902-1912
Author(s):  
Naama Assayag ◽  
Yoram Bonneh ◽  
Shula Parush ◽  
Haim Mell ◽  
Ricky Kaplan Neeman ◽  
...  

Abstract Objective This comparative cross-sectional study aimed to characterize individuals with substance use disorder (SUD) in self-perception of pain sensitivity, experimental auditory aversiveness, and non-noxious sensory responsiveness, as well as examine the associations with SUD. Methods Therapeutic community (TC) individuals with SUD (N = 63, male 88.9%) and healthy controls (N = 60, male 86.7%) completed the Pain Sensitivity Questionnaire (PSQ) and the Sensory Responsiveness Questionnaire–Intensity Scale (SRQ-IS), followed by a psychophysical auditory battery, the Battery of Averseness to Sounds (BAS)–Revised. Results The SUD group scored higher on the PSQ (P < 0.0001), BAS-R aversiveness (P < 0.0001), BAS-R-unpleasantness (P < 0.0001), and on the aftersensation of auditory aversiveness (P < 0.0001) and unpleasantness (P < 0.000). Fifty-four percent of the SUD group vs 11.7% of the control group were identified as having sensory modulation dysfunction (SMD; P < 0.0001). Logistic regression modeling revealed that the SRQ-IS-Aversive score had a stronger relationship, indicating a 12.6-times odds ratio for SUD (P = 0.0002). Finally, a risk score calculated from a linear combination of the logistic regression model parameters is presented based on the PSQ and SRQ. Conclusions This is the first study to explore sensory and aversive domains using experimental and self-reporting in situ, revealing pain perception alteration that co-occurs with high prevalence of SMD, specifically of the over-responsive type. Findings may be significant in clinical practice for treating pain, and for expanding therapeutic modalities as part of broader rehabilitation in TC and beyond, to better meet personalized therapy.

2019 ◽  
pp. 030573561985452 ◽  
Author(s):  
Michael J. Silverman

While many people use music for emotion regulation, there is a dearth of empirical inquiry investigating if music-based self-regulatory factors correlate with and predict coping in adults with substance use disorder (SUD). The purpose of this cross-sectional study was to explore music-based emotion regulation, healthy and unhealthy music use, and coping strategies in adults with SUD on a detoxification unit via correlational and multiple regression analyses. Participants ( N = 194) completed the Brief Music in Mood Regulation Scale, the Healthy-Unhealthy Music Scale, and the Brief COPE. Correlations and multiple regression analyses were conducted to determine which music-based emotion regulation factors were related to and predicted coping. There were a plethora of significant relationships between music-based factors and coping. Regression results indicated that solace predicted acceptance and entertainment predicted venting. Healthy music use predicted active coping and humor, while unhealthy music use predicted venting, denial, behavioral disengagement, and self-blame. Generally, unhealthy music use predicted maladaptive coping while healthy music use predicted adaptive coping. As music use is common for people with SUD, it seems that music-based emotion regulation training may have the possibility to augment adaptive coping skills with the ultimate goal of increasing the likelihood of recovery.


2020 ◽  
Vol 32 (3) ◽  
pp. 574-578
Author(s):  
Nugehally Raju Ramesh Masthi ◽  
Manasa Avverahally Ravi

Background: Substance use is a significant problem in our societies and is increasing day by day due to factors like easy availability, rapid socioeconomic changes, etc. The professional degree students are at risk as they are exposed to high levels of stress and competition. Aim & Objective: To find out the burden of substance use among young adults in professional degree colleges, to assess the effect of substance use on health among study subjects, to compare the health status between substance users and non-users. Settings and Design: This cross-sectional study was conducted among students studying in various professional degree colleges of Urban Bengaluru between July 2017 to December 2017. Methods and Material: A total of 1400 study subjects were included and administered a pre-tested, semi structured questionnaire and relevant information was obtained using Alcohol, Smoking and Substance Involvement Screening Test (WHO ASSIST) V3.0 scale. Statistical analysis used: Data was entered using MS Excel 2016 and was analysed in Stata 12.1 (Stata Corp, Texas, USA). Z test for proportions, Univariate logistic regression and Multivariate logistic regression were used as appropriate. Results: The overall prevalence of substance use was 35%. Dizziness was the most common health symptoms observed in substance users. Male, students staying in hostels/ paying guest, foreign nationals, substance use in the family and presence of conflict were found to be significant risk factors for substance use. Conclusions: The burden of substance use was observed in about one third of the subjects. Substance use was significantly associated with health problems.


2016 ◽  
Vol 5 (46) ◽  
pp. 2870-2873
Author(s):  
Dalia Mokhtar Khalil ◽  
Khalid Saad Sherra ◽  
Hesham Mahmoud Abuhegazy ◽  
Nagda El masry M ◽  
Ahmed Kamel ◽  
...  

2021 ◽  
Author(s):  
Saeed Amiri ◽  
Hajar Shekarchizadeh

Abstract Background Little is known about the effect of illicit drugs on oral health-related quality of life. Our aim was to investigate oral health-related quality among patients with substance use disorder, and its association with dental caries experience and drug use profile. Methods Applying a stratified cluster random sampling method, we conducted a cross-sectional study on 267 in-treatment patients with substance use disorder in Isfahan, Iran in 2016. Self-administered questionnaires requested participants’ demographics and drug use profile. A trained dental student carried out personal interviews utilizing Oral Impact on Daily Performance (OIDP) instrument. Clinical examinations were conducted to record dental caries experience. T-test, ANOVA, pearson and spearman correlation coefficient, and linear regression model served for statistical analysis (p < 0.05). Results A great majority of the participants reported past use of opium (85%) followed by heroin (42.7%) and amphetamines (20.2%). The most common routes of drug administration were combined routes (44.6%) followed by smoking (36.7%). The mean score of OIDP was 22.4 ± 8.6. As high as 74.1% of the participants reported at least one OIDP impact. The most prevalent OIDP impact was “difficulty eating” (64.8%). The most prevalent cause of the impacts were “dental decay” and “tooth loss”. No significant association revealed between OIDP and patients’ demographics and drug use profile (p > 0.05). Participants with higher caries experience, reported greater OIDP (p < 0.05). Conclusions There is an oral impact on the daily performance of patients with substance use disorder. Patients with higher caries experience reported greater OIDP. Thus, in addition to normative assessment of oral health, clinicians should consider the patients' self-reported oral problems, and the social and mental aspects of oral conditions.


2021 ◽  
Vol 4 (2) ◽  
pp. 19-26
Author(s):  
CN Nwoga ◽  
DD Dapap ◽  
AY Armiya'u ◽  
MD Audu ◽  
SG Goar ◽  
...  

Substance use disorder are among the most common public health problems caused by using legal and/or illegal substances. Therefore, this study is aimed at reviewing a five-year profile of women admitted at a rehabilitation center in Jos, Nigeria for substance use and mental illness. This is a retrospective cross-sectional study carried out on 183 females admitted between 2012 and 2017 at a rehabilitation center in Jos, Nigeria. Data collection was carried out from documents note of these female participants. Data were analyzed using SPSS version 22. The mean age of the participants was 38.515.3 years. Almost half of the participants were within the age bracket of 20 – 29 years and married (45.9%). Depressive disorder (36.1%) was the commonest mental disorder in the studied participants. Among those abusing substances, multiple substance use (12.6%) was the most prevalent with alcohol use disorder (9.3%) the main diagnosis among those with substance use disorder. According to the result almost half of the studied participants were young, married and educated females. Depression and multiple substance abuse with alcohol the main drug of abuse was a cause for concern in this population. This portrays significant health and economic consequences and the need for urgent action.


Author(s):  
Inmaculada Riquelme ◽  
Isabel Escobio-Prieto ◽  
Ángel Oliva-Pascual-Vaca ◽  
Alberto Marcos Heredia-Rizo ◽  
Pedro Montoya

Pain and abnormal somatosensory processing are important associated conditions in children and adolescents with cerebral palsy (CP). Perceived social support is highly relevant for pain perception and coping. Aim: The aim of the present study was to assess the influence of social support on pain sensitivity in children and adolescents with cerebral palsy and healthy peers. Design: Cross-sectional study. Methods: Pressure pain thresholds were assessed in 42 children and adolescents with CP and 190 healthy peers during three different conditions: alone, with their mother and with a stranger. Results: Children with CP reported lower pain sensitivity when they were with their mother than being alone or with a stranger, whereas healthy peers did not experience different pain sensitivity related to the social condition. Sex or clinical characteristics did not affect the relationship between pain perception and social support. Conclusion: The present study shows how children with CP are highly affected by social and contextual influences for regulating pain sensitivity. Solicitous parental support may enhance pain perception in children with CP. Further research on the topic is warranted in order to attain well-founded conclusions for clinical practice.


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