scholarly journals FactFinders for Patient Safety: Are Gadolinium-Based Contrast Media Safe Alternatives to Iodinated Contrast Agents for the Safe Performance of Spinal Injection Procedures?

Pain Medicine ◽  
2018 ◽  
Author(s):  
Adrian Popescu ◽  
Jaymin Patel ◽  
Zachary L McCormick ◽  
Timothy P Maus ◽  
Meghan Rodes ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Richard Solomon

Iodinated contrast agents are usually classified based upon their osmolality—high, low, and isosmolar. Iodinated contrast agents are also nephrotoxic in some but not all patients resulting in loss of glomerular filtration rate. Over the past 30 years, nephrotoxicity has been linked to osmolality although the precise mechanism underlying such a link has been elusive. Improvements in our understanding of the pathogenesis of nephrotoxicity and prospective randomized clinical trials have attempted to further explore the relationship between osmolality and nephrotoxicity. In this review, the basis for our current understanding that there are little if any differences in nephrotoxic potential between low and isosmolar contrast media will be detailed using data from clinical studies.


2016 ◽  
Vol 6 (1) ◽  
pp. 12-15
Author(s):  
Şerife Mehlika Kuşkonmaz ◽  
Sema Yıldız

In parallel to the increased use of computed tomography, iodinated contrast agents are increasingly becoming a source of excess iodide. Iodinated contrast agents may induce thyroid dysfunction in exposed patients, especially in the presence of an underlying thyroid disease. Thus, an ordinary dose of the contrast used for the imaging, can induce hyper or hypothyroidism in a patient with subtle thyroid disease. This review will briefly discuss the physiology of iodine and the clinical evaluation of iodine induced thyroid dysfunction.


PEDIATRICS ◽  
1972 ◽  
Vol 49 (1) ◽  
pp. 116-118
Author(s):  
Thomas E. Shea ◽  
Richard C. Pfister

A young child demonstrating opacification of the gallbladder following intravenous urography is described. This is the fourth reported instance of this phenomenon occurring in childhood although it is probably not a rare occurrence. Factors promoting the heterotopic biliary excretion of renal contrast media include prolonged recirculation of urographic contrast agents because of reduction in glomerular filtration rate due to intrinsic renal disease or ureteral obstruction; the current propensity for high doses of iodinated contrast agents for urography; gallbladder stasis; and, possibly, increased protein binding of urographic contrast media in the presence of uremic acidosis.


2017 ◽  
Vol 25 (4) ◽  
pp. 697-704 ◽  
Author(s):  
Maria Vittoria Spampinato ◽  
Ahad Abid ◽  
Maria Gisele Matheus

Author(s):  
Umashankar Lakshmanadoss ◽  
John Lindsley ◽  
Daryl Glick ◽  
Charles H. Twilley ◽  
John J. Lewin ◽  
...  

1999 ◽  
Vol 6 (5) ◽  
pp. 193-198 ◽  
Author(s):  
LOKESH C. ARORA ◽  
SACHIKO T. COCHRAN

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