scholarly journals Effects of Acupuncture Treatment on Fibromyalgia Symptoms, Serotonin, and Substance P Levels: A Randomized Sham and Placebo-Controlled Clinical Trial

Pain Medicine ◽  
2017 ◽  
Vol 19 (3) ◽  
pp. 615-628 ◽  
Author(s):  
Saliha Karatay ◽  
Sibel Caglar Okur ◽  
Hulya Uzkeser ◽  
Kadir Yildirim ◽  
Fatih Akcay
Keyword(s):  
Clinical Trial ◽  
Substance P ◽  
Acupuncture Treatment ◽  
Controlled Clinical Trial

scholarly journals Acupuncture treatment for ischaemic stroke in young adults: protocol for a randomised, sham-controlled clinical trial

BMJ Open ◽  
2016 ◽  
Vol 6 (1) ◽  
pp. e010073 ◽  
Author(s):  
Lifang Chen ◽  
Jianqiao Fang ◽  
Xiaoming Jin ◽  
Crystal Lynn Keeler ◽  
Hong Gao ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Acupuncture Treatment ◽  
Controlled Clinical Trial ◽  
Stroke In Young Adults ◽  
Stroke In Young

Effect of Acupuncture in the Treatment of Seasonal Allergic Rhinitis: A Randomized Controlled Clinical Trial

2002 ◽  
Vol 30 (01) ◽  
pp. 1-11 ◽  
Author(s):  
Charlie Changli Xue ◽  
Robert English ◽  
Jerry Jiansheng Zhang ◽  
Cliff Da Costa ◽  
Chun Guang Li
Keyword(s):  
Clinical Trial ◽  
Allergic Rhinitis ◽  
Treatment Group ◽  
Seasonal Allergic Rhinitis ◽  
Acupuncture Treatment ◽  
Sham Acupuncture ◽  
Syndrome Differentiation ◽  
Controlled Clinical Trial ◽  
Safe Alternative ◽  
Real Acupuncture

The clinical efficacy and safety of acupuncture in the treatment of Seasonal Allergic Rhinitis (SAR) was evaluated by employing a two-phase crossover single-blind clinical trial. Thirty subjects were randomly assigned to two groups with 17 and 13 subjects respectively and treated with real or sham acupuncture (three times per week) for four consecutive weeks and then a crossover for treatments for a further four weeks without a washout period. The administration of real acupuncture treatment was guided by a syndrome differentiation according to Chinese Medicine Theory. Subjects were assessed by various criteria before, during and after the treatments. Outcome measures included subjective symptom scores using a five-point scale (FPS), relief medication scores (RMS) and adverse effect records. Twenty-six (26) subjects completed the study. There was a significant improvement in FPS (nasal and non-nasal symptoms) between the two types of acupuncture treatments. No significant differences were shown in RMS between the real acupuncture treatment group and the sham acupuncture treatment group. No side effects were observed for both groups. The results indicate that acupuncture is an effective and safe alternative treatment for the management of SAR.

scholarly journals Effect of Acupuncture on Gut-Brain Axis Parameters in Patients with Atopic Dermatitis: A Study Protocol for a Randomized, Participant- and Assessor-Blind, Sham-Controlled Trial

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Jundong Kim ◽  
Soon-Kyeong Kwon ◽  
In-Seon Lee ◽  
Mijung Yeom ◽  
Dae-Hyun Hahm ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Atopic Dermatitis ◽  
Acupuncture Treatment ◽  
Underlying Mechanism ◽  
Patient Specific ◽  
Skin Barrier Function ◽  
Controlled Clinical Trial ◽  
Acupuncture Points ◽  
Specific Response ◽  
Gi Symptoms

Atopic dermatitis (AD) is a relapsing and remitting chronic inflammatory skin disease for which a variety of etiological factors are involved. Treatment strategies should be multifaceted and have few side effects. In this respect, acupuncture has become increasingly popular as a safe, consistently effective, and drug-free therapy that treats multiple AD symptoms. We aim to not only verify the effectiveness of acupuncture but also suggest patient-specific response determinants and a new underlying mechanism implicating the gut-brain axis. We have designed a randomized, participant-blinded, sham-controlled clinical trial for 60 mild to moderate AD patients. In a previous study, we observed that the clinical skin symptoms of AD were closely associated with gastrointestinal (GI) symptoms. From these findings, we developed an intervention with six acupuncture points: three for AD symptoms and three for GI symptoms. Also, since high responders and low responders to the acupuncture treatment could be identified in the previous study, we now aim to explore response-determining factors, with a particular focus on GI symptoms. Therefore, we will precisely evaluate not only AD symptoms using the SCORAD, EASI, and DLQI tools, but also GI symptoms using the GSRS, TDS, BSFS, and AR tools and abdominal examination. AD develops in association with complicated pathophysiological factors, such as skin barrier function, genetic susceptibility, and immunological factors. Moreover, the underlying mechanism by which acupuncture treatment works has not been clearly elucidated. We, therefore, will conduct a simultaneous cross-sectional study with a sample of 40 healthy individuals, wherein potential indicators, such as fMRI, gut microbiota, and serum TARC and ATX, will be investigated to determine the gut-brain axis-associated mechanism of acupuncture. We expect that the results of this study could provide important clinical evidence for the effects of acupuncture and help elucidate the therapeutic mechanisms that underlie acupuncture’s efficacy in AD treatment. This trial is registered with https://clinicaltrials.gov/ct2/show/KCT0005422 (Trial registration: Korean Clinical Trial Registry (http://cris.nih.go.kr; registration number: KCT0005422); date of registration: September 23, 2020).

scholarly journals Longitudinal Anti-Müllerian Hormone in Women with Polycystic Ovary Syndrome: An Acupuncture Randomized Clinical Trial

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Jason Franasiak ◽  
Steven L. Young ◽  
Christopher D. Williams ◽  
Lisa M. Pastore
Keyword(s):  
Clinical Trial ◽  
Polycystic Ovary Syndrome ◽  
Acupuncture Treatment ◽  
Polycystic Ovary ◽  
Ovarian Follicle ◽  
Sham Acupuncture ◽  
Controlled Clinical Trial ◽  
Ovary Syndrome ◽  
Double Blind ◽  
The Impact

Others have studied acupuncture treatment for polycystic ovary syndrome (PCOS). Anti-müllerian hormone (AMH) is positively correlated with the ovarian follicle pool, thus making it a useful ovarian reserve measure. AMH is elevated in women with PCOS and has been suggested as a diagnostic tool. This study examined the impact of electroacupuncture on AMH concentration in women with PCOS. Seventy-one women with PCOS participated in a randomized, double-blind, sham-controlled clinical trial of acupuncture. Three longitudinal AMH samples over the 5-month protocol were compared with objective ovulation parameters primarily using nonparametric statistics. Results indicated that AMH levels in PCOS were higher than published norms in women without PCOS. There was no difference between the true and sham acupuncture arms in the change in AMH longitudinally. Baseline AMH, but not the change in AMH over time, was inversely correlated with ovulation and menstrual cycle frequencies in both arms combined (). In conclusion, AMH correlated with an increased likelihood of monthly ovulation, as expected from the literature on women without PCOS. The lack of difference by intervention in AMH was consistent with the underlying clinical trial. AMH may be clinically useful to predict which PCOS women are more likely to respond to an intervention.

Multicomponential VR-Enhanced Treatment of Emotional Overeating in Obese Subjects: A Controlled Clinical Trial

2006 ◽  
Author(s):  
Gian Mauro Manzoni ◽  
Gian Luca Cesa ◽  
Daniela Villani ◽  
Gianluca Castelnuovo Enrico Molinari ◽  
Giuseppe Riva
Keyword(s):  
Clinical Trial ◽  
Controlled Clinical Trial ◽  
Obese Subjects
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