Nitric Oxide Production Mediated by Nitrate Reductase in the Green Alga Chlamydomonas reinhardtii: an Alternative NO Production Pathway in Photosynthetic Organisms

2002 ◽  
Vol 43 (3) ◽  
pp. 290-297 ◽  
Author(s):  
Yasuko Sakihama ◽  
Soichi Nakamura ◽  
Hideo Yamasaki
Keyword(s):  
Nitric Oxide ◽  
Nitrate Reductase ◽  
Chlamydomonas Reinhardtii ◽  
Green Alga ◽  
No Production ◽  
Nitric Oxide Production ◽  
Photosynthetic Organisms ◽  
Oxide Production

scholarly journals The Nitric Oxide Production in the Moss Physcomitrella patens Is Mediated by Nitrate Reductase

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0119400 ◽  
Author(s):  
Rigoberto Medina-Andrés ◽  
Alejandro Solano-Peralta ◽  
Juan Pablo Saucedo-Vázquez ◽  
Selene Napsucialy-Mendivil ◽  
Jaime Arturo Pimentel-Cabrera ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitrate Reductase ◽  
Physcomitrella Patens ◽  
Nitric Oxide Production ◽  
Oxide Production

LeSPL-CNR negatively regulates Cd acquisition through repressing nitrate reductase-mediated nitric oxide production in tomato

Planta ◽  
2018 ◽  
Vol 248 (4) ◽  
pp. 893-907 ◽  
Author(s):  
Wei Wei Chen ◽  
Jian Feng Jin ◽  
He Qiang Lou ◽  
Li Liu ◽  
Leon V. Kochian ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitrate Reductase ◽  
Nitric Oxide Production ◽  
Oxide Production

scholarly journals Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts

2009 ◽  
Vol 2 (4) ◽  
pp. 245-249 ◽  
Author(s):  
Eun-Jin Yang ◽  
Eun-Young Yim ◽  
Gwanpil Song ◽  
Gi-Ok Kim ◽  
Chang-Gu Hyun
Keyword(s):  
Nitric Oxide ◽  
Plant Extracts ◽  
Inhibitory Activity ◽  
Inflammatory Diseases ◽  
No Production ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Potent Inhibition

Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extractsNitric oxide (NO) produced in large amounts by inducible nitric oxide synthase (iNOS) is known to be responsible for the vasodilation and hypotension observed during septic shock and inflammation. Thus, inhibitors of iNOS may be useful candidates for the treatment of inflammatory diseases accompanied by the overproduction of NO. In this study, we prepared alcoholic extracts of Jeju plants and screened them for their inhibitory activity against NO production in lipopolysaccharide (LPS)-activated macrophages. Among the 260 kinds of plant extract tested, 122 extracts showed potent inhibitory activity towards NO production by more than 25% at a concentration of 100 μg/mL. Plants such asMalus sieboldii, Vaccinium oldhamii, Corylus hallaisanensis, Carpinus laxiflora, Styrax obassia, andSecurinega suffruticosashowed the most potent inhibition (above 70%) at a concentration of 100 μg/mL. The cytotoxic effects of the plant extracts were determined by colorimetric MTT assays and most plant extracts exhibited only moderate cytotoxicity at 100 μg/mL. Therefore, these plants should be considered promising candidates for the further purification of bioactive compounds and would be useful for the treatment of inflammatory diseases accompanying overproduction of NO.

scholarly journals A Dirofilaria immitis Polyprotein Up-Regulates Nitric Oxide Production

2002 ◽  
Vol 70 (9) ◽  
pp. 5283-5286 ◽  
Author(s):  
Hiroyuki Tezuka ◽  
Shinjiro Imai ◽  
Setsuko Tsukidate ◽  
Koichiro Fujita
Keyword(s):  
Nitric Oxide ◽  
Dirofilaria Immitis ◽  
Peritoneal Macrophages ◽  
No Production ◽  
Nitric Oxide Production ◽  
Wild Type ◽  
Murine Macrophages ◽  
Oxide Production

ABSTRACT We investigated the effect of recombinant Dirofilaria immitis polyprotein (rDiAg) on nitric oxide (NO) production by peritoneal macrophages. rDiAg induced NO production by macrophages from wild-type and lipopolysaccharide-hyporesponsive C3H/HeJ, but not CD40−/−, mice. These results suggest that CD40 is involved in rDiAg-driven NO production by murine macrophages.

scholarly journals Nitrate Reductase is Responsible for Elicitin-induced Nitric Oxide Production in Nicotiana benthamiana

2006 ◽  
Vol 47 (6) ◽  
pp. 726-735 ◽  
Author(s):  
Ayako Yamamoto-Katou ◽  
Shinpei Katou ◽  
Hirofumi Yoshioka ◽  
Noriyuki Doke ◽  
Kazuhito Kawakita
Keyword(s):  
Nitric Oxide ◽  
Nitrate Reductase ◽  
Nicotiana Benthamiana ◽  
Nitric Oxide Production ◽  
Oxide Production

scholarly journals Adenosine Regulates Renal Nitric Oxide Production in Hypothyroid Rats

1999 ◽  
Vol 10 (8) ◽  
pp. 1681-1688
Author(s):  
MARTHA FRANCO ◽  
EDILIA TAPIA ◽  
FLAVIO MARTÍNEZ ◽  
MA. EUGENIA DAVILA ◽  
JUANA INÉS GRIMALDO ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Renal Function ◽  
Urinary Excretion ◽  
Kidney Function ◽  
Normal Values ◽  
Inhibitory Effect ◽  
No Production ◽  
Nitric Oxide Production ◽  
Nitric Oxide Synthesis ◽  
Oxide Production

Abstract. In the hypothyroid kidney, exogenous adenosine (ADO) produces vasodilation and restores renal function to near-normal values. This study evaluates whether this response is mediated by nitric oxide synthesis stimulated by adenosine. GFR and urinary excretion of NO2-/NO3- (UNO2-/NO3-) were measured in normal (NL) and hypothyroid (HTX) rats under basal conditions and during infusion of: intra-aortic ADO, intravenously, 1,3-dipropyl-8p-sulfophenylxanthine (DPSPX), 8-cyclopentyl-1,3-dipropyl xanthine (DPCPX), Nω-nitro-L-arginine methylester (L-NAME) + ADO, L-NAME + PSPX, L-NAME + DPCPX, and intrarenal (IR) ADO or DPCPX + IR ADO. Intra-aortic ADO induced a fall in GFR and increased UNO2-/NO3- slightly in NL rats; in HTX rats, both GFR and UNO2-/NO3- increased significantly. DPSPX and DPCPX increased UNO2-/NO3- excretion in NL animals with minor changes in GFR; the blockers increased both GFR and UNO2-/NO3- in HTX rats. L-NAME completely blocked the increase in NO2-/NO3- induced by ADO, DPSPX, and DPCPX. The intrarenal infusion of ADO at 1, 10, and 35 nmol/kg per min progressively decreased GFR with a slight increase in UNO2-/NO3- in NL rats; in the HTX, GFR increased with the highest dose and UNO2-/NO3- progressively increased. DPCPX prevented the fall in GFR induced by intrarenal ADO in NL rats, with no further changes in UNO2-/NO3-; in HTX rats, intrarenal ADO under A1 blockade further increased GFR and UNO2-/NO3-. Arterial and venous ADO concentrations were lower in the HTX rats. In the HTX kidney, NO production was stimulated by ADO, most likely through activation of A2 or A3 receptors, whereas A1 receptors had an inhibitory effect. Thus, ADO receptors are involved in the regulation of kidney function in pathophysiologic conditions.

Sign in / Sign up

Export Citation Format

Share Document