scholarly journals Implementing the Bedside Paediatric Early Warning System in a community hospital: A prospective observational study

2011 ◽  
Vol 16 (3) ◽  
pp. e18-e22 ◽  
Author(s):  
Christopher S Parshuram ◽  
Ann Bayliss ◽  
Janette Reimer ◽  
Kristen Middaugh ◽  
Nadeene Blanchard
BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e032187
Author(s):  
Jonathan Arnold ◽  
Alex Davis ◽  
Baruch Fischhoff ◽  
Emmanuelle Yecies ◽  
Jon Grace ◽  
...  

ObjectiveOur study compares physician judgement with an automated early warning system (EWS) for predicting clinical deterioration of hospitalised general internal medicine patients.DesignProspective observational study of clinical predictions made at the end of the daytime work-shift for an academic general internal medicine floor team compared with the risk assessment from an automated EWS collected at the same time.SettingInternal medicine teaching wards at a single tertiary care academic medical centre in the USA.ParticipantsIntern physicians working on the internal medicine wards and an automated EWS (Rothman Index by PeraHealth).OutcomeClinical deterioration within 24 hours including cardiac or pulmonary arrest, rapid response team activation or unscheduled intensive care unit transfer.ResultsWe collected predictions for 1874 patient days and saw 35 clinical deteriorations (1.9%). The area under the receiver operating curve (AUROC) for the EWS was 0.73 vs 0.70 for physicians (p=0.571). A linear regression model combining physician and EWS predictions had an AUROC of 0.75, outperforming physicians (p=0.016) and the EWS (p=0.05).ConclusionsThere is no significant difference in the performance of the EWS and physicians in predicting clinical deterioration at 24 hours on an inpatient general medicine ward. A combined model outperformed either alone. The EWS and physicians identify partially overlapping sets of at-risk patients suggesting they rely on different cues or decision rules for their predictions.Trial registration numberNCT02648828.


Biology ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 257
Author(s):  
Nunzia La Maida ◽  
Esther Papaseit ◽  
Lucia Martínez ◽  
Clara Pérez-Mañá ◽  
Lourdes Poyatos ◽  
...  

Synthetic cannabinoids (SCs) are one of the most frequent classes of new psychoactive substances monitored by the EU Early Warning System and World Health Organization. UR-144 is a SC with a relative low affinity for the CB1 receptor with respect to that for the CB2 receptor. As with other cannabinoid receptor agonists, it has been monitored by the EU Early Warning System since 2012 for severe adverse effects on consumers. Since data for UR-144 human pharmacology are very limited, an observational study was carried out to evaluate its acute pharmacological effects following its administration using a cannabis joint as term of comparison. Disposition of UR-144 and delta-9-tetrahydrocannibinol (THC) was investigated in oral fluid. Sixteen volunteers smoked a joint prepared with tobacco and 1 or 1.5 mg dose of UR-144 (n = 8) or cannabis flowering tops containing 10 or 20 mg THC (n = 8). Physiological variables including systolic and diastolic blood pressure, heart rate and cutaneous temperature were measured. A set of Visual Analog Scales (VAS), the Addiction Research Centre Inventory (ARCI)-49-item short form version and the Evaluation of the Subjective Effects of Substances with Abuse Potential (VESSPA-SSE) were administered to evaluate subjective effects. Oral fluid was collected at baseline, 10, 20, 40 min and 1, 2, 3 and 4 h after smoking, for UR-144 or THC concentration monitoring. Results showed significant statistical increases in both systolic and diastolic blood pressure and heart rate after both UR-144 and cannabis smoking. Both substances produced an increase in VAS related to stimulant-like and high effects, but scores were significantly higher after cannabis administration. No hallucinogenic effects were observed. Maximal oral fluid UR-144 and THC concentrations appeared at 20 and 10 min after smoking, respectively. The presence of UR-144 in oral fluid constitutes a non-invasive biomarker of SC consumption. The results of this observational study provide valuable preliminary data of the pharmacological effects of UR-144, showing a similar profile of cardiovascular effects in comparison with THC but lower intensity of subjective effects. Our results have to be confirmed by research in a larger sample to extensively clarify pharmacological effects and the health risk profile of UR-144.


2020 ◽  
Vol 6 (2) ◽  
pp. 112
Author(s):  
Veronika Hutabarat ◽  
Enie Novieastari ◽  
Satinah Satinah

Salah satu faktor dalam meningkatkan penerapan keselamatan pasien adalah ketersediaan dan efektifitas prasarana dalam rumah sakit. Early warning system (EWS) merupakan prasarana dalam mendeteksi perubahan dini  kondisi pasien. Penatalaksanaan EWS masih kurang efektif karena parameter dan nilai rentang scorenya belum sesuai dengan kondisi pasien. Tujuan penulisan untuk mengidentifikasi efektifitas EWS dalam penerapan keselamatan pasien. Metode penulisan action research melalui proses diagnosa, planning action, intervensi, evaluasi dan  refleksi. Responden dalam penelitian ini adalah  perawat yang bertugas di area respirasi dan pasien dengan kasus kompleks respirasi di Rumah Sakit Pusat Rujukan Pernapasan Persahabatan Jakarta. Analisis masalah dilakukan dengan menggunakan diagram fishbone. Masalah yang muncul belum optimalnya implementasi early warning system dalam penerapan keselamatan pasien. Hasilnya 100% perawat mengatakan REWS membantu mendeteksi kondisi pasien, 97,4 % perawat mengatakan lebih efektif dan 92,3 % perawat mengatakan lebih efesien mendeteksi perubahan kondisi pasien. Modifikasi EWS menjadi REWS lebih efektif dan efesien dilakukan karena disesuaikan dengan jenis dan kekhususan Rumah Sakit dan berdampak terhadap kualitas asuhan keperawatan dalam menerapkan keselamatan pasien. Rekomendasi perlu dilakukan monitoring evaluasi terhadap implementasi t.erhadap implementasi REWS dan pengembangan aplikasi berbasis tehnologi


PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 256A-256A
Author(s):  
Catherine Ross ◽  
Iliana Harrysson ◽  
Lynda Knight ◽  
Veena Goel ◽  
Sarah Poole ◽  
...  

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