scholarly journals First-in-Human Experience With Integration of a Hydrocephalus Shunt Device Within a Customized Cranial Implant

2019 ◽  
Vol 17 (6) ◽  
pp. 608-615 ◽  
Author(s):  
Chad R Gordon ◽  
Amir Wolff ◽  
Gabriel F Santiago ◽  
Kenneth Liebman ◽  
Erol Veznedaroglu ◽  
...  

AbstractBACKGROUNDImplantable shunt devices are critical and life saving for hydrocephalus patients. However, these devices are fraught with high complication rates including scalp dehiscence, exposure, and extrusion. In fact, high shunt valve profiles are correlated with increased complications compared to those with lower profiles. As such, we sought a new method for integrating shunt valves for those challenging patients presenting with scalp-related complications.OBJECTIVETo safely implant and integrate a hydrocephalus shunt valve device within a customized cranial implant, in an effort to limit its high-profile nature as a main contributor to shunt failure and scalp breakdown, and at the same time, improve patient satisfaction by preventing contour deformity.METHODSA 64-yr-old male presented with an extruding hydrocephalus shunt valve and chronic, open scalp wound. The shunt valve was removed and temporary shunt externalization was performed. He received 2 wk of culture-directed antibiotics. Next, a contralateral craniectomy was performed allowing a new shunt valve system to be implanted within a low-profile, customized cranial implant. All efforts were made, at the patient's request, to decrease the high-profile nature of the shunt valve contributing to his most recent complication.RESULTSFirst-in-human implantation was performed without complication. Postoperative shunt identification and programming was uncomplicated. The high-profile nature of the shunt valve was decreased by 87%. At 10 mo, the patient has experienced no complications and is extremely satisfied with his appearance.CONCLUSIONThis first-in-human experience suggests that a high-profile hydrocephalus shunt device may be safely integrated within a customized cranial implant.

2011 ◽  
Vol 2 (1) ◽  
pp. 59-88 ◽  
Author(s):  
Thang NGUYEN DANG

Joint petroleum development has often been considered as a viable solution to the seemingly intractable Spratly Islands dispute in the South China Sea (SCS). This is, however, more easily said than done. On the other hand, little attention is paid to fisheries co-operation in the SCS despite the fact that fisheries constitute an important part in the economies of coastal states. The present laissez-faire approach to fisheries in the disputed area gives rise to friction and tension. By highlighting the salient features of existing fisheries’ co-operative arrangements in the world, this article demonstrates the merits of a fisheries arrangement in the SCS. It also argues that fisheries co-operation, as a low-profile undertaking, is probably easier to achieve than joint petroleum development. A fisheries arrangement would serve the immediate interests of parties to the Spratly Islands dispute and may pave the way for their future high-profile co-operation, i.e. joint petroleum development.


2007 ◽  
Vol 3 (4) ◽  
pp. 225 ◽  
Author(s):  
Chong Shen

In this paper, we address mobility management for 4th generation heterogeneous networks from a quality of service (QoS), optimisation and cross layer design perspective. Users are classified as high profile, normal profile and low profile according to their differentiated service requirements. Congestion avoidance control and adaptive handover mechanisms are implemented for efficient cooperation within the mobile heterogeneous network environment consisting of a TDMA network, ad hoc network and relay nodes. A previous proposed routing algorithm is also revised to include mobility management.


2021 ◽  
Vol 11 (1) ◽  
pp. 42
Author(s):  
Pita Rahmawati ◽  
Jawoto Nusantoro ◽  
Gustin Padwa Sari

This research aims to determine whether there are differences in stock prices, stock returns and abnormal returns before and after a stock split in high profile and low profile companies. The research period used in this study was on 2016-2018. The research was analyzed in quantitative method by using a purposive sampling method. Based on the sampling criteria, 40 companies were selected as research samples. Kolmogorov Smirnov One Sample test was used for the normality test. After the normality test was carried out, the data was processed using the two paired-sample difference test. The t-test (paired sample t-test) was used if data were normally distributed but if it was not normally distributed the Wilcoxon Signed Rank test would be used. Hypothesis testing results showed that (1) there are differences in stock prices whether before and after a stock split in high profile companies (2) there are differences in stock prices whether before and after the stock split in low profile companies (3) there are differences in stock returns whether before and after a stock split in the company high profile (4) there is no difference in stock returns whether before and after the stock split in low profile companies (5) there is no difference in abnormal returns whether before and after the stock split in high profile companies (6) there is no difference in abnormal returns whether before and after the stock split in low profile companies (7) there are differences in stock prices after a stock split in high profile companies and low profile (8) there is no difference in stock returns whether before and after the stock split in high profile and low profile companies (9) there is no difference in abnormal stock returns whether before and after a stock split at high profile and low profile companies.


Author(s):  
Anson W. Mackay ◽  
Rebecca Lee ◽  
James M. Russell

Abstract Rwenzori Mountains National Park, which straddles the border between the Democratic Republic of Congo and Uganda, has experienced rapid glacier loss since the beginning of the twentieth century, yet there has been little investigation of aquatic biodiversity change in the park. This study presents a paleolimnological analysis from Lake Mahoma (2990 m asl), which is situated in the bamboo-forest transition zone. Diatom and organic geochemistry data from a 39-cm-long sediment core with a basal age of c. 1715 CE were compared with new analyses of previously published data from Lakes Bujuku (3891 m asl) and Lower Kitandara (3989 m asl), in the alpine zone. Comparisons were made to determine if aquatic ecosystem changes exhibited similar inter-lake patterns over the past ~ 150 years of climate warming and glacial recession, or if only local change was apparent. The diatom flora of Lake Mahoma is acidophilous, dominated by Aulacoseira ikapoënsis since at least the mid eighteenth century. In recent decades, the obligate nitrogen-heterotroph Nitzschia palea increased in importance, concurrent with declining δ15Norg values. We suggest that these late twentieth century changes were linked to regional warming and increased thermal stratification of Lake Mahoma. Regional comparisons of the Rwenzori lakes were done using existing organic geochemistry records (total organic carbon, C/N and δ13Corg) and through diatom compositional turnover analyses, and categorisation of species into one of four diatom growth morphology traits, or guilds: tychoplanktonic, high-profile, low-profile and motile. Over the past 150 years, all three lakes showed unidirectional, compositional diatom turnover, indicating that deterministic processes had affected diatom communities. Declining turnover at each site is broadly mirrored by an increase in tychoplanktonic taxa, along with concomitant declines in high-profile diatoms at Lake Mahoma, and low-profile diatoms at Lake Bujuku, and at least for the past 60 years, at Lower Kitandara. The interplay between diatom guilds at all sites is mainly a consequence of competition for available resources. Sediment organic carbon at all sites comes from both autochthonous and allochthonous sources, the relative abundances of which are influenced by the time elapsed since lakes had glaciers in their catchment.


2010 ◽  
Vol 11 (7-8) ◽  
pp. 881-889 ◽  
Author(s):  
Thomas Burri

With the request for an advisory opinion on Kosovo opportunity knocked on the doors of the International Court of Justice. The opportunity was unique for several reasons. First, the case of Kosovo was momentous. It had involved war. International armed forces had intervened to stop ethnic cleansing. Since then, the situation of Kosovo has been politically loaded. It has polarized the entire international community. Second, it is a rare occurrence that such a situation comes to the Court. The regular case, if there is such a thing, before the Court has tended to be a relatively low-profile interstate dispute. The Kosovo incidence had only come to the Court in the first place—like the case of the Wall on the West Bank, the other recent high-profile exception—because the detour via the United Nations General Assembly had been open.


2020 ◽  
Vol 5 (1) ◽  
pp. 247301141989496
Author(s):  
Dominic S. Carreira ◽  
Steven R. Garden ◽  
Thomas Ueland

The role of arthroscopy in the management of ankle and hindfoot pathology management has increased greatly in recent years with the potential for lower complication rates, faster recovery, improved access, and improved outcomes when compared to open techniques. Procedural variations exist as techniques aim to optimize lesion access, decrease operative time, and improve patient safety. Our goal is to summarize the described approaches and patient positionings common in minimally invasive arthroscopic surgery for anterior, lateral, and posterior ankle pathologies. A survey of pathology organized by arthroscopic approach and a review of recent advances in concomitant lesion management may be useful when planning arthroscopic foot and ankle surgery. Level of Evidence: Level V, expert opinion.


Significance This followed Qatar's December 14 rejection of Egyptian charges that it had assisted the Islamist perpetrator of a bomb attack on a cathedral in Cairo. The accusation is the legacy of a pre-2013 era of activist foreign policy and support for the Muslim Brotherhood. Under pressure from Saudi Arabia and others, the country has since returned to the Gulf Arab fold, but relations with Egypt remain tense. Impacts Even if recovering energy prices ease the fiscal situation in 2017, foreign policy is likely to be cautious. The legacy of previous unsuccessful mediation efforts in Yemen could compromise Qatar’s role in conflict-resolution efforts. Qatar is not as strongly involved in Libya as before, but maintains low-profile ties with Tripolitanian, Islamist-leaning groups. Ties with Riyadh could strengthen further after a high-profile visit by King Salman on December 5.


2012 ◽  
Vol 17 (4) ◽  
pp. 56-66 ◽  
Author(s):  
Tracey Yeadon-Lee

This paper contributes to a growing body of scholarship concerned with hairstyling as an occupation and, more broadly, to sociological discussions concerning contemporary forms of service work. As an occupation hairstyling is largely under-researched, with the majority of existing studies restricting their focus to small low-profile salons situated in the ‘backstreets’ of rural areas or small towns. Hairstyling in larger high-profile salons, such as those in city centres, has only recently begun to be explored and critical discussion of existing knowledge in light of these environments has yet to be fully developed. The aim of this paper is to stimulate such discussion by examining how the work practices and service interactions of hair stylists in high-profile salons within the UK impact upon their status and identities in relation to clients. Research undertaken in low-profile salon settings has found that the service-oriented and commercial features of the work position stylists as subservient to clients and undermines their ‘expert’ status. Drawing on empirical qualitative research this paper shows how in contemporary high-profile salon environments, which need to manage a tension between the high cost of the service being provided and a poor ‘low-skilled’ occupational reputation, stylist-client dynamics are differently configured. It highlights how service orientated norms and practices underpinning the work of stylists are informed by discourses of customer service ‘excellence’ which promote employee proactivity and discourage customer deference. Discussion of the data shows how stylists working in high-profile salons are empowered to be directive in their service interactions with clients and engage in range of work practices which facilitate, rather than undermine, the establishment of their expert status. The relevance of the research findings to understandings of status and identity construction in service work jobs within similar high-profile settings is also highlighted in the paper.


2021 ◽  
Author(s):  
Andreas Jungherr ◽  
Alexander Wuttke ◽  
Matthias Mader ◽  
Harald Schoen

Abstract Interest groups increasingly communicate with the public, yet we know little about how effective they are in shaping opinions. Since interest groups differ from other public communicators, we propose a theory of interest group persuasion. Interest groups typically have a low public profile, and so most people are unlikely to have strong attitudes regarding them. Source-related predispositions, such as credibility assessments, are therefore less relevant in moderating effects of persuasive appeals by interest groups than those of high-profile communicators. We test this argument in multiple large-scale studies. A parallel survey and field experiment (N = 4,659) establishes the persuasive potential of low-profile interest groups in both controlled and realistic settings. An observational study (N = 700) shows that substantial portions of the public are unable to assess interest group credibility. A survey experiment (N = 8,245) demonstrates that credibility assessments moderate the impact of party but not interest group communication.


1970 ◽  
Vol 7 (1) ◽  
pp. 19-24
Author(s):  
A Joshi ◽  
BR K.C. ◽  
P Chand ◽  
BB Thapa

Background: Among various fixation methods for metacarpal fractures, plate osteosynthesis is the most rigid and allows early rehabilitation leading to early return to work. Many authors have reported high complication rates and most of them were because of thick plate. The aim of this study was to report early results of plate osteosynthesis of metacarpal fractures with low profile miniplate. Methods: This was a hospital based prospective study. Unstable and irreducible fractures were managed by open reduction and internal fixation with low profile miniplate and were followed up for 6 months. The functional outcome after fracture treatment was assessed by ability to perform acts of daily life and calculating American Society for Surgery of the Hand Total Active Flexion (ASSH TAF) score. Results: There were 16 patients with 17 metacarpal fractures, 87.5% were male with mean age of 31.50±9.02 years. Fourteen (87.5%) patients could perform their activities of daily living at four weeks. The mean Total Active Flexion was 261.76±24.87 at final follow up. Fourteen (87.5%) patients had excellent, one (6.25%) good and one (6.25%) poor out come at the end of 6 months. Conclusion: Low severity metacarpal fractures can be treated successfully by open reduction internal fixation with low-profile miniplate, allowing early and safe mobilization. Key words: low-profile plate, metacarpal fractures, plate osteosynthesis   DOI: 10.3126/jnhrc.v7i1.2274 Journal of Nepal Health Research Council Vol. 7, No. 1, 2009 April 19-24


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